8JJ5


Conserved Protein Domain Family
Uroplakin_II

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pfam07353: Uroplakin_II (This model is not part of the current CDD release)
Uroplakin II
This family contains uroplakin II, which is approximately 180 residues long and seems to be restricted to mammals. Uroplakin II is an integral membrane protein, and is one of the components of the apical plaques of mammalian urothelium formed by the asymmetric unit membrane - this is believed to play a role in strengthening the urothelial apical surface to prevent the cells from rupturing during bladder distension.
Statistics
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PSSM-Id: 517678
Aligned: 3 rows
Threshold Bit Score: 294.583
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
8JJ5_B         6 PVRTLPLILILLAVLAPGASDFNISSLSGPLSPALTESLLVALPPCHLTGGNATLMVRRANDSKVVKSSFMVPPCRGRRE 85  pig
P38575         6 PVQTLPLILILLAVLAPGTADFNISSLSGLLSPALTESLLIALPPCHLTGGNATLMVRRANDSKVVKSDFVVPPCRGRRE 85  house mouse
XP_001380648  19 amsflmptllllvlPHLGSAEFNISSLSGLLSPALAESLLVALPPCHLTGGKASLTVRRVNESAGMTHNFTVPPCRARRD 98  gray short-tail...
8JJ5_B        86 LVSVVDSGSGFTVTRLSAYQVTNLVPGTKYYISYLVTKGASTESSREIPMSTLPRRKAEAIGLGMAPTGGMVVIQVLLSV 165 pig
P38575        86 LVSVVDSGSGYTVTRLSAYQVTNLTPGTKYYISYRVQKGTSTESSPETPMSTLPRKNMESIGLGMARTGGMVVITVLLSV 165 house mouse
XP_001380648  99 LVSVVYNSGSFSITRLSAYQVTNLIPGTKYFVYYSVEKGTAVESSNKVQMATLPRRKVETLGLGMARTGGMIVITVLLSV 178 gray short-tail...
8JJ5_B       166 AMFLLVVGFITALALGARK 184 pig
P38575       166 AMFLLVVGLIVALHWDARK 184 house mouse
XP_001380648 179 AMFLLVVGLIVALALGVHK 197 gray short-tailed opossum
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