Conserved Protein Domain Family
Amastin

?
pfam07344: Amastin 
Amastin surface glycoprotein
This family contains the eukaryotic surface glycoprotein amastin (approximately 180 residues long).In Trypanosoma cruzi, amastin is particularly abundant during the amastigote stage.
Statistics
?
PSSM-Id: 399964
View PSSM: pfam07344
Aligned: 73 rows
Threshold Bit Score: 81.1235
Threshold Setting Gi: 74833202
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
CAM39684     143 WVHLLFVILSA-TLSQ--I-DLVGG-----------SCYTFWG--YKENCDTVSYTRRTALL--MNC----TRLRSNMHT 199 Leishmania braz...
Q4QHJ3       241 FISGCVLTIATvGTAQnmWehyd---------rttsLKITYWGveIYHRNESLSENWPLSSY---HC----PQLTLHMRA 304 Leishmania major
Q4E0S1        20 CISFVFATVST-PTSQ--F-RGKGYldggk--esklSCVTAWG--VKNECTSNKYDLRSSEI---KCegndKRLHQLFQT 88  Trypanosoma cruzi
XP_001566731  20 CTVFMFLVTSA-PISQ--F-RGSGIradgsggasklACVTSWG--LKNDCNSNHYDYRSTSI---TC----ARPRQLFQV 86  Leishmania braz...
XP_001466937  20 CIVFMFLVTSA-PISQ--F-RGRGInasatggasklSCVTVWG--LKNDCNANNYDYRPTSI---GC----ARSKQLFQV 86  Leishmania infa...
Q4CVL1        26 MVSFIFFVIGT-PIAM--L-QPKLSp---------gTCYTLWG---TRACNSPNYDWRVNw---DTC----KARRLRFQF 82  Trypanosoma cruzi
CAM69987      26 FVTATFTVCGT-PLGMlmIrSWGEDlsgssaelelnPCFTLWG--LHSDCSKPDYSLRITDSpiVNC----SDMHVRFEA 98  Leishmania infa...
CAM39651     158 SIAFVFTLAAAcPIPW--Y-RGKNVeesgv--nyneRTFNLWK------AEGGNYSAVSVRTm-KDC----PVEKQFYQT 221 Leishmania braz...
CAM37226     152 TVAFIFHLTSScPIPW--M-RSSSG-----------RKYGVWR-----ATGGGEPDLKVSDI--HDC----SYEMQYWQA 206 Leishmania braz...
Q4QHJ4       134 AAAFVCHLTSScPIPW--M-RGESG-----------RKYGVWR-----ATGGGQPDLEVSDI--HDC----SYEMQSWKA 188 Leishmania major
CAM39684     200 GSAFAILSILASTVTVVTSWLLCIRfreadrearhqcryvnvddaesiageanfnnggahntkqaneavydaGNLKKLMM 279 Leishmania braz...
Q4QHJ3       305 AAVLSIISDAFLFPTFLFSVAAVYS-----------------------------------------------RPCKWVTV 337 Leishmania major
Q4E0S1        89 TQAFSIISIFLTFASIITVGMLFNG-----------------------------------------------KSTRRLTL 121 Trypanosoma cruzi
XP_001566731  87 AQAFYIIAVIVSFLSSLLSGLYFMG-----------------------------------------------IKAKVALI 119 Leishmania braz...
XP_001466937  87 SEAFYILAVIVSFLSCLMSGLYFMG-----------------------------------------------IKAKVLLV 119 Leishmania infa...
Q4CVL1        83 GEAFSICALYFAVVAGIGSWYVLSG-----------------------------------------------SKKKWLTV 115 Trypanosoma cruzi
CAM69987      99 AEAFSILAIFSLVGLFGASWYMICG-----------------------------------------------SKIKKAVM 131 Leishmania infa...
CAM39651     222 IAVCTIVGCALSLVSLLITGARLVG-----------------------------------------------RSSYGWIL 254 Leishmania braz...
CAM37226     207 VAATSVLATFASCGAMISGVLLCVN-----------------------------------------------KGHMAASF 239 Leishmania braz...
Q4QHJ4       189 AAAMSVLATVTSFGAMISGVLLCVN-----------------------------------------------KGHMGASF 221 Leishmania major
CAM39684     280 IVVALGLVCELICWAIITDINTQQYC-NdiYHW------------------STDaTYGV------------------GFG 322 Leishmania braz...
Q4QHJ3       338 GFGAVSWTLLLACSAITIAARYKTFC-PsgVVP------------------PSTaIYGApldtveqrvnfkgfvitdGLG 398 Leishmania major
Q4E0S1       122 LLAVASVAALLIPWACMAAVYKGSFC-G--TVFhd--------------nwRRDwKYSS------------------AFG 166 Trypanosoma cruzi
XP_001566731 120 VLGFLEVVVALIPWVCMTAVWHNDYCgQ--STVvinassgkangvpygsvlRTAfKMSA------------------GYG 179 Leishmania braz...
XP_001466937 120 LLAVLEVMFALIPWVCMTAVWYGNYC-GgsTVKintssgkad-gvphgsvlRESfKVSA------------------GYG 179 Leishmania infa...
Q4CVL1       116 IASAISTVSGLVTWSMVASIHNVKLC-GsdTYT------------------SANtKYGP------------------GFA 158 Trypanosoma cruzi
CAM69987     132 LLAVFAIGSTTVPWAIVTAFYYTPFC-GldFLT------------------NTHtRFGA------------------GYA 174 Leishmania infa...
CAM39651     255 LFSFLAFLWTLCGNAMSIRLYYAPRCdA--PQF------------------SHTaRLDV------------------GFA 296 Leishmania braz...
CAM37226     240 ILSFFSISFSLISWALVVALYRYFRC-GkgAFA------------------SGVaHLDG------------------GYA 282 Leishmania braz...
Q4QHJ4       222 ILSFYSFFFSLVSWALVVALYHSFRC-GkgTFA------------------GGVaHLDA------------------GVA 264 Leishmania major
CAM39684     323 LGLTGWLAELIMYVIF 338 Leishmania braziliensis MHOM/BR/75/M2904
Q4QHJ3       399 MIISAWCITTANLIYL 414 Leishmania major
Q4E0S1       167 LFLGGWLVQLVGTVFL 182 Trypanosoma cruzi
XP_001566731 180 MTVTAWCVQVVGLTLL 195 Leishmania braziliensis MHOM/BR/75/M2904
XP_001466937 180 LTVAAWCTQVIGLVLL 195 Leishmania infantum JPCM5
Q4CVL1       159 LFVTGFVVQFCGLLGL 174 Trypanosoma cruzi
CAM69987     175 LLVTSFVLQIVGLILF 190 Leishmania infantum JPCM5
CAM39651     297 LSLLAWIFQLCGFLAL 312 Leishmania braziliensis MHOM/BR/75/M2904
CAM37226     283 LTLIGWVMHMTAIIVL 298 Leishmania braziliensis MHOM/BR/75/M2904
Q4QHJ4       265 LMLIGWVMHIVAFTVL 280 Leishmania major
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap