pfam07282: Cas12f1-like_TNB (This model is not part of the current CDD release)
Cas12f1-like, TNB domain
This entry represents a zinc ribbon domain known as the target nucleic acid-binding (TNB) domain of CRISPR-associated endodeoxyribonuclease Cas12f1 and similar sequences found in all domains in life. This domain is also found in bacterial transposases, including putative transposes described by [pfam01385]. Some proteins containing this domain, in particular, Cas12m orthologues, albeit containing D-E-D, H-D-D and N-D-D motifs in the RuvC active site do not exhibit dsDNA nuclease activity, but efficiently bind to dsDNA targets in a PAM-dependent manner. The DNA-binding activity without cleavage seems is a common feature of the Cas12m effectors.
Jiyao W et al.(2023). "The conserved domain database in 2023.",