5MQH,3ES2,3KE6,6K4E


Conserved Protein Domain Family
SpoIIE
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pfam07228: SpoIIE (This model is not part of the current CDD release)
Stage II sporulation protein E (SpoIIE)
This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.
Links
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Statistics
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PSSM-Id: 517618
Aligned: 156 rows
Threshold Bit Score: 73.8287
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5MQH_A   39 GARKYAIAISDGMGNGARAHFESNETIKLLEKIL-ESGID-------------EKIAIKTINSILslrtTDE-----IYS 99   Bacillus subtilis
Q87HB6  190 DEQHVAFYVFDVSGHGISSALMSFSIQKTLSRSC-GPESVttdlvegeyvvsePNVVVERLNLRYqq-tPDSq----LYF 263  Vibrio parahaemolyt...
Q8DJR9  187 GDRYLVLYILDVSGHGLGAALPSVSVLNLLRSTT-REQTSgtfd------yrhPAQVLEALNNGFqmtaQHE-----KYF 254  Synechococcus elong...
Q8YQR0  199 DDEHLAIYLLDVSGHGIGSALLSVSILNILRSQS-LPNTNfy----------kPREVLKALNHAFqmtnHGD-----KYF 262  Nostoc sp. PCC 7120
Q81H20  189 DENRYGIILLDVMGHGVSASLVCMFISSVLRETI-KCLID-------------PELVIKELNKYMtl-lHNEndnipYYF 253  Bacillus cereus ATC...
O07014  215 DEHRYGIIILDVMGHGISSALITMSLHPLFQRQI-TQGLS-------------PVKVMKELDRHLhslfQNDee-arHYC 279  Bacillus subtilis s...
Q8F451  481 GVEYQVLINADAMGKSLQGASGALIFCSIVKSFLqTQDYEfr----------nPENWLFLLYSNLqavfESFdg--sMLV 548  Leptospira interrogans
Q8F9X0  686 YKRYTMVMNGDAMGKSMQGAGGALVMGVVMNSIM-ARSAAnnri-----ldktPSEWLEDVYNEIhavfKSFng--sMVI 757  Leptospira interrogans
Q8F9W7  688 ykRYVFAMNGDAMGKSMQGAGGALVMGVVVNSIL-ARSAAndri-----ldisPEQWLTETYEEInsvfKSFng--sMVI 759  Leptospira interrogans
Q8F082  495 NRKCLVFVNGDAMGKSIQGASGALVLGVVFRSFI-SRTKTvssy-----hskpPELWLKECFLELqnifESFdg--sMLV 566  Leptospira interrogans

5MQH_A  100 TLDLSIiDLQDASCKFLKVGSTPSFIKRGDQ------VMKVQASNLP--IGIINE-FDVEVVSEQLKAGDLLIMMSDGIF 170  Bacillus subtilis
Q87HB6  264 TIVYAVlNTQTGKLRYCTAGHPKFLWRHQSEa----tIDMVGDENFI--VGALAP-MQYKGGEITLEPNDSIWCFSDGVV 336  Vibrio parahaemolyt...
Q8DJR9  255 TIWYGVyDRQTRQLTYASGGHPPALLLAPKAaq--wqATLLKTPGIP--IGMFAE-MVFTQATIEVPPSAVLYLFSDGVY 329  Synechococcus elong...
Q8YQR0  263 TIWYGVyHCIQHQLVYASAGHPPAVILSG-TsetgfqVKQLNSLDLP--IGFLPD-VQFEDAAWEVKKDSTLYIFSDGIY 338  Nostoc sp. PCC 7120
Q81H20  254 TAIYLVvNTEDRTVEYVNAGHPSGYVLVD-Et----nVVELDRGSCA--VGFFDE-IKVEKTVIPFEKNAQIVLFTDGVL 325  Bacillus cereus ATC...
O07014  280 TAIYLEiDIARQRIDYVNAGHPPALWQDD-Sg----tQHLLHATSPP--IGMFED-LEFQSSSLSYTEDGRLLLYTDGVM 351  Bacillus subtilis s...
Q8F451  549 SGILSLyQISTGDLFFINCEHPPMVLSRNg------kTSYLKETAVLrkIGFPDSdSKIKVEYYKLLPGDTILYGSDGRE 622  Leptospira interrogans
Q8F9X0  758 SATIFLiEEESGKCFYFNAEHPFTVLYRDg------kASFLEEGLQLrkLGLDSE-FDFQVRTFELKKGDVLILGSDGRD 830  Leptospira interrogans
Q8F9W7  760 SASFFLiEESSGKTYYFNAEHPFTVFYQDg------kATFLDSSLMLrkIGLESE-YPFQVFTTTLKEGDVLIVGSDGKD 832  Leptospira interrogans
Q8F082  567 SVVLGLvDLESGVLFFLNAEHPPTVLYRN-Gv----aTFIENKLELRk-IGITGLeSKMKVKTFFLEKGDTIIVSSDGRD 640  Leptospira interrogans

5MQH_A  171 EGPkhveNHDLWMKRKMKGL--KTNd------PQEIADLLMEEVIR--------TRSGQIEDDMTVVVVRID 226  Bacillus subtilis
Q87HB6  337 EAR-----YENEFFSVNRLI--ANVqsvsglpFEAQVSSVVESIKRw-------QVKEELDDDLTLLQLQWF 394  Vibrio parahaemolyticus
Q8DJR9  330 EFE----TTDHQIWGLDAFR--DLLitahtqnPVPPLSQLISQVQRh------aAPAGFGSDDVSLVQVAFP 389  Synechococcus elongatus
Q8YQR0  339 EIR----EPDGKILGLDAFI--EILikssqaePCNIHYILMQIMTL--------NIQQIIEDDLSLLKITLG 396  Nostoc sp. PCC 7120
Q81H20  326 E------AIANDEFEAEEKL--RTFterkwgdLEGEIEGFYKEEQK---------K--AQSDDMCLIMIQTN 378  Bacillus cereus ATCC 14579
O07014  352 -------DPTASCYLFDLLK--DHPds----pIADLKEKILTSLQHq-------KEAHHKSDDECFILVDVK 403  Bacillus subtilis subsp. su...
Q8F451  623 DL-----YIQDPFYSSQKQKss---------vPDLFFKLIQNSIPKledlefkiQEKGTLSDDLSFLRIQIG 680  Leptospira interrogans
Q8F9X0  831 DIDltpeETVRTINEDENLF--LVNve----kGKGNLEDIESEIRK--------HG--ELTDDLSLLKVEFQ 886  Leptospira interrogans
Q8F9W7  833 DLDlt-pDQDTRTINEDETLflKTVeig--kgNIEQIEQLIYKEG-------------EITDDLSLLRIEyg 888  Leptospira interrogans
Q8F082  641 DILlg-mDQDGIPLINEDEC--QFLrrv--eeSGGDLDLLVQGLEN--------YG--ELTDDLSIVKLTYL 697  Leptospira interrogans
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