Conserved Protein Domain Family
LcrG
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pfam07216: LcrG 
LcrG protein
This family consists of several bacterial LcrG proteins. Yersiniae are equipped with the Yop virulon, an apparatus that allows extracellular bacteria to deliver toxic Yop proteins inside the host cell cytosol in order to sabotage the communication networks of the host cell or even to cause cell death. LcrG is a component of the Yop virulon involved in the regulation of secretion of the Yops.
Links
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Statistics
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PSSM-Id: 284601
Aligned: 4 rows
Threshold Bit Score: 104.852
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q87P58  6 TQAIENAELAIRNADERNDIFSELLEGLGVGPVAGEVLLGGLNASpkLMQHAEQELIEEVQRRRQQQHQlQGVQGKRRKR 85  Vibrio parahaemolyticus
Q7N0X0  7 AKVLQAAEAAIKDSDHRLQLLQEMWQSLGINPNVGTELFGHTDVT--LVQNAEQELLTEVNRLRSNQPP-SLEEGKRLRR 83  Photorhabdus laumondii...
P69957 10 DKTLKQAELAIADSDHRAKLLQEMCADIGLTPEAVMKIFAGRSAE--EIKPAERELLDEIKRQRERQPQ-HPYDGKRPRK 86  Yersinia pestis
Q9I326 13 RATVQAAELAIRDSEERGRLLAEMWQGLGLAADAGELLFQAPERE--LARAAEEELLAELRRMRSSQPT-QGEQGTRPRR 89  Pseudomonas aeruginosa

Q87P58 86 PTMMRGMVI 94  Vibrio parahaemolyticus
Q7N0X0 84 PPRMRGIIV 92  Photorhabdus laumondii subsp. laumondii
P69957 87 PTMMRGQII 95  Yersinia pestis
Q9I326 90 PTPMRGLLI 98  Pseudomonas aeruginosa
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