1U0S


Conserved Protein Domain Family
P2
?
pfam07194: P2 (This model is not part of the current CDD release)
P2 response regulator binding domain
The response regulators for CheA bind to the P2 domain, which is found between pfam01627 and pfam02895 as either one or two copies. Highly flexible linkers connect P2 to the rest of CheA and impart remarkable mobility to the P2 domain. This feature is thought to enhance the inter CheA dimer phosphotransfer reactions within the signalling complex, thereby amplifying the phosphorylation signal.
Links
?
Statistics
?
PSSM-Id: 517603
Aligned: 177 rows
Threshold Bit Score: 48.2786
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
1U0S_A                 6 YIKVILKEGTQLKSARIYLVFHKLEELkCEVVRTIPsvEEIEEek------fENEVELFV--I-S-PVDLEKLSEALsS- 74  Thermot...
WP_015393691         176 SATLFFEELCEMENIRCFTVVHKLKEV-SEVCYFYP--EDIIEnnetceiikQEGFKVFL--K-T-NYSLKNIKEFL-Me 247 Clostri...
Q0AXB4               175 HALIYFTPGCEMENIRAFNLVHKLKDQ-AEQIDYIP--ADIIEnndsvefirENGFAVIF--T-T-HLQQEAINELF-Mk 246 Syntrop...
WP_013486382         179 TAHLVFEEGGQMENLRAFNIVRNLTEY-TVELYTNP--TDLLGtpse--tilQKGFDIFF--S-T-AEPEERMRSLF-De 248 Ethanol...
goetting:Curi_c08390 158 KVRIHFEEGCGMENIRAYTIIHKMKDF-SDIEEFIP--GDIVEnedsakeiiKKGFEITF--N-T-SEDKTFIKEFL-Nn 229
WP_014356272         170 HINVSYEDDCMMENIRAYTLIFGLTEL-VDELYFFP--ADITEnsetaeyirENGFDIYL--K-A-AIEDEELEAYL-Nk 241 Acetoba...
CDE37279             171 RIHIFYRADTQMSNLRAYTAVYSLKEI-AEDILYKP--EDIVTneasadvilADGFQMML--Q-T-QSSKEKIEKLId-- 241
WP_004602623         191 fIHIFLEEGVGMENLRAFMIVNAVKEC-EIDFRFYP--EDMEHnsdcaqqiiDNGFFMAF----NtPEDSEKALSVLqS- 262 [Eubact...
WP_014355901         172 QVILEFEEDCGMENIRAFTVIHNLKEL-TETFKSIP--EDVINdpdcveiikRDGFILQI--R-I-AESIEKLTAFF-Sa 243 Acetoba...
WP_014356826         203 CIHTRFKEDSQMENIRAFMLVNKLESI-GKVSKKKP--EQLNNnpeaagiilKNGFYCHLetTaN-KETIENIAMSIlS- 277 Acetoba...

1U0S_A                75 IADIERVII 83  Thermotoga maritima
WP_015393691         248 TVFLNRVDI 256 Clostridium saccharoperbutylacetonicum
Q0AXB4               247 EAFIDSLDL 255 Syntrophomonas wolfei subsp. wolfei str. Goettingen G311
WP_013486382         249 SLYLKSYEL 257 Ethanoligenens harbinense
goetting:Curi_c08390 230 SAFLKEYHL 238
WP_014356272         242 ILYIEKFSI 250 Acetobacterium woodii
CDE37279             242 GSGVEKIDI 250
WP_004602623         263 QGHIRSYEV 271 [Eubacterium] cellulosolvens
WP_014355901         244 MAFIETVKV 252 Acetobacterium woodii
WP_014356826         278 VKSIEfvdc 286 Acetobacterium woodii
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap