Conserved Protein Domain Family
SKA1

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pfam07160: SKA1 
Spindle and kinetochore-associated protein 1
Spindle and kinetochore-associated protein 1 (SKA1) is a component of the SKA1 complex (consists of Ska1, Ska2, and Ska3/Rama1), a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.
Statistics
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PSSM-Id: 399856
View PSSM: pfam07160
Aligned: 34 rows
Threshold Bit Score: 180.94
Threshold Setting Gi: 675888162
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EFJ46034      15 IAELQRLSSLRl--dDQTKEYyHQDLLGLEANVQALEEQVAALKAFVQSELSVMPKVEaLIEASRIQSER-TNIVAKNLP 91  Volvox carteri ...
EGT56085      16 lATYRE------------------NIPNFDPTIAHLAGSIQNIRSTLQDISKANENLKeCCEATC------ANCLPLNLN 71  Caenorhabditis ...
Q9XWS0        16 FRICRE------------------NIPNFETTISPLLNTMKNIKLLLDDAAFDQQKLEnNCEETC------MNCTKSQLN 71  Caenorhabditis ...
A8WS92        16 FCMYRE------------------NIPNFESTLSSITKSTNSIKILLEDISNVQKVITdPCEQSC------SSCSPNVLN 71  Caenorhabditis ...
XP_006683095  35 IQLLRELVSVHaaatSSQPTAlSHILSDLSHQISTLESQAADLQQALDTETTLLGHGRsNILPKLKQQESvLIQMLDKVN 114 Batrachochytriu...
2_pfamImport   2 VRELNRRVQIL----DGYDDTsEECLKLLE-SVKEIKFLISERKKILQNNQMIIEDRMqLVNRLRTLQTR-MAYMNVNYP 75 
Q9LZZ7        21 IGELQELVIAR----NMYPAStIPDLSAIDTALSSMELQVQSIKDRLREETEAIPKAKkLIEASLKQQGK-LQKMSIYAP 95  thale cress
XP_015163390  21 ISEIQQLVVAR----NMYPASsVSDLSAIDSALKVLELQLHKIKIRMREETEAIPKAKkLIEASLRQQKK-LQNLSSVVP 95  potato
KRH76175      21 ITQLQELVIAR----NMYPASgVEDLSAVDAAVSAMELQVKAIKDRLREEALAIPKTKkLIDASLRQQKK-LQNMSLHVP 95  soybean
CBI38876      21 ITELQELVIGR----NMYPASsITDLTAVDASLKAMELQVQAIKDRLRDEIEAIPKAKkLIDASLRQQKK-LQSMYSYVP 95  wine grape
EFJ46034      92 ARLPRQVACSVQgvSLAPSRPGAVgagqldalqtgsklaaGGTAAGTGVTVNGgedagrrRKEAPRWYVTEREFEAASSY 171 Volvox carteri ...
EGT56085      72 SLLGIKTENNRNeeAPTKIIHGDEktev---------akqNDKTNLETEKTED-------NEVRFVAQVSDQEFKTIPKY 135 Caenorhabditis ...
Q9XWS0        72 DFLGIKVEASTIvdVKSQLVPQSKessal-------vetnEPNEQGLSSKPKE-------NDIRIVPQITDEEFKTIPKY 137 Caenorhabditis ...
A8WS92        72 KFLGIEEKLVNNveIPDSVPQKSTrpc-----------ldDEKEGSSVVQPPE-------SGNRHVQLISEQEFKSIPKY 133 Caenorhabditis ...
XP_006683095 115 AG---GTHATSTehTADVSDTLTFmkvasasdtngepdadPTSHAPKKEKPSA-------KPCRSIRLLTDDEYNHIPQY 184 Batrachochytriu...
2_pfamImport  76 RGVIIFEDDRSPdrVDSVEVPSENatisqnnytspqpeadRTTLTVPTPKPRG-------DLQISVSYVSNLEFQNVPPY 148
Q9LZZ7        96 SHFPDKATMLNSdlNRCLLQEnakqyeqh---stlsslkfDEEAAVLPKEKKG-------RGSPPLWYITVEELNSLSSY 165 thale cress
XP_015163390  96 SYVPDRVTKTTDdaTKCLNLEpiveds-------fvslklEE---PAPKEKKG-------RVSPPLFYISSDELNSVPPY 158 potato
KRH76175      96 YQMADKVTVSHLetSRCLFPEfsgqdsg-----sfealklEEEPAAVPKEKKG-------RGPPPTWYVTRSELDSLSSY 163 soybean
CBI38876      96 SNFPDRVAPSNLesSKSLMSEtskqctn------fgsekhEEEPAAPPKEKKG-------RAPPPLWFITIDELDSLSSY 162 wine grape
EFJ46034     172 LRGRLQTDKVNAALDELAGHALNNSKLIAAVKgggTKLA-PADRKRATELLHSv-aMKDGIKGHYWFLESDLREG----- 244 Volvox carteri ...
EGT56085     136 QLGRLTRDNLNEIVQKMDEFLMKKNQIFGKSN---KQLT-RIDRELLDNWKELelkARGRLQTTLFFVEADIRPL----- 206 Caenorhabditis ...
Q9XWS0       138 QLGRLTLEMMNEIVSKMDDFLMKKSKILGKTN---KQLT-RSDREVLDNWRELemkARKRLPTTLFFIETDIRPM----- 208 Caenorhabditis ...
A8WS92       134 QLGRLTLDNLNEIVGKMDEFLTKKNAILGKTN---KQIT-RQDREVLDNWRELeikAKGRLPTTLFFIENDIRPL----- 204 Caenorhabditis ...
XP_006683095 185 IVGRITLEKINQAITDLNLLISDKYKIFKLPQ---QKMS-KLQRSIYWEHKQL---ATAETKSRVFVTEKDLKDKsggwt 257 Batrachochytriu...
2_pfamImport 149 MKGRLKVTDVNKFIDAYNNTLTQKYELLKRPK---NTIKvKSELDKFINWKSQ---MNSDTAGLHFCTSDDFFTE----- 217
Q9LZZ7       166 MRGRLTLEKVNAAINDMASYAEANAHLIAASK---QKLA-ENLWEKALKLRDIv--TEQAVKGKHFFLETDMKG------ 233 thale cress
XP_015163390 159 MKQRITLEKVNAAINDMATYAEATSQLLTAPR---KKLK-ENLVERAMELRDIa--ATETVKGKHFFLETDIRG------ 226 potato
KRH76175     164 MRGRLTLEKVNAAINDMVSYAEANAQLIVAPK---KKLA-ENLWEKALEIRDIa--TMEGIKGKHFFLEADIKG------ 231 soybean
CBI38876     163 MRGRLTLEKVNAAINDMATYAEANAQLIAAPK---KKLA-ENVWERALEIRDIa--MTGGVKGKHFFLETDIKG------ 230 wine grape
EFJ46034     245 -TAIKLDKTGKSMLTLLRHLGRLQEAAI 271 Volvox carteri f. nagariensis
EGT56085     207 -LQERLRPTFSKAIPCLRHIRRIREERC 233 Caenorhabditis brenneri
Q9XWS0       209 -LQDRLRPSFAKAIPCLRHIRRIREERC 235 Caenorhabditis elegans
A8WS92       205 -LTERLRLSFAKAIPCLRHIRRVREERC 231 Caenorhabditis briggsae
XP_006683095 258 eSGFKFDAVGRNVVAILRHLGRIKEVRG 285 Batrachochytrium dendrobatidis JAM81
2_pfamImport 218 -SGIKFGKKEFSLVTVLRHTKRIREIR- 243
Q9LZZ7       234 -PSLKLDNTGKAILTVLRHLGRISETRI 260 thale cress
XP_015163390 227 -PSLKLDNTGKAILTLLRHLGRISETRI 253 potato
KRH76175     232 -PSLKLDNTGKAILTVLRHLGRINETRV 258 soybean
CBI38876     231 -PALKLDNTGRAILTVLRHLGRISEIRI 257 wine grape
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