6WVD


Conserved Protein Domain Family
Jagunal
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pfam07086: Jagunal (This model is not part of the current CDD release)
Jagunal, ER re-organisation during oogenesis
Jagunal is an endoplasmic-reticulum (ER)-membrane protein found in eukaryotes. It is involved in reorganising the ER in cells that must increase exocytic membrane traffic during development, that is, in the oocyte during vitellogenesis. It facilitates vesicular traffic in the subcortex.
Links
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Statistics
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PSSM-Id: 517555
Aligned: 29 rows
Threshold Bit Score: 171.294
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6WVD_A       143 MASRAGPRAAGTDGSDFQHRERVAMHYQMSVTLKYEIKKLIYVHLVIWLLLVAKMSVGHLRLL--------SHDQVAM-- 212 synthetic const...
XP_003728147   1 MSSKGGPRAAGTDGSDFQHREQVASQYKTSVQLKSKFRTCLYINILVVLIQVVMFAGAHFHI-------------IPSdf 67 
XP_516267      1 MASRAGPRAAGTDGSDFQHRERVAMHYQMSVTLKYEIKKLIYVHLVIWLLLVAKMSVGHLRLl--------SHDQVAM-- 70 
XP_027284898   1 MASRAGPRAAGTDGSDFQHRERVAMHYQMSVTLKSEIKKLIYVHLVIWLLLVAKMCVGHLRLl--------SHDQVAM-- 70 
XP_005995812   1 MASRLGPRAAGTDGSDFQHREKVASHYQMSVVLKSKIKKLTCAQIVVWLLIAARVLVSYLKLv--------SSDLIAV-- 70 
XP_005807878   1 MASRAGPRASGTDGSDFQHRERVASHYQMSVALKSEIRKLNIVHVLIWVLMAAQVTVSQLSLv--------SHKVVAS-- 70 
XP_003961803   1 MTSRVGPRSAGPNGS-VKHRERVAPNYQMSSSLKSEVRKLNLVHLLIWLLVAAQVTVSHLNLv--------SHDTVSM-- 69 
Q5XJX0         1 MASRAGPRAAGTDGGDFKHREKVASHYQMSASSKSEIKKLTVVHFLIWILVAAQVAVSHLNLv--------SHDLVAM-- 70  zebrafish
XP_018655169   1 MASRVGHRPEGTDGADFRHRERVCTQYSLSPLLKRRIKFVYFLHLMLWVLMFARLLPELCLRLgfrtrlmvEKWPFPQ-- 78 
XP_002127629   1 MSSYSGKTVAGSDGSDHSFREKVASQYKTSASLKSTIKTLFLLSFLPMLVVLIHIMQEDLEIRf-------LNVDLPQ-- 71 

6WVD_A       213 -PYQWEYPYLL-SILPSLLGLLSFPRNNISYLVLSMISMGLFSIAPLIYGSMEMFPAAQQLYRHGKaYR-FLFGFSAVSI 289 synthetic const...
XP_003728147  68 yPSPWQYTWML-SGVVSLIGLNALAKNKKEMLSLHDLGLTIFGFGGIFFGFTSQYSSHQRYIASGEtKR--IADIPLHYI 144
XP_516267     71 -PYQWEYPYLL-SILPSLLGLLSFPRNNISYLVLSMISMGLFSIAPLIYGSMEMFPAAQQLYRHGKaYR-FLFGFSAVSV 147
XP_027284898  71 -PYQWEYPYLL-SIVPSLLGLLSFPRNNISYLVLSMISMGLFSIAPLIYGSMEMFPAAQQLYRHGKaYR-FLFGFSAVSV 147
XP_005995812  71 -PFQWEYPYLL-SIIPCIFGFMCLPRNNISYLVLSMISTGLFSISPLIFGSMEMFPMAQQLYRHGKgNR-FIFGFSAVSV 147
XP_005807878  71 -PYQWEYPYLL-SIVPTVFSFLALPRNNISYLVVSMISAGLFCVAPLIYGGMEMFPVAQQLYRHGKaYR-FIFGFSAVSV 147
XP_003961803  70 -PYQWEYPYLL-SLVPLLCSSLSLPKNNISYLVLSMISGGLFSVAPLIYGSMEMFPVAQQLYRHGKaYR-FIFGFSAVTV 146
Q5XJX0        71 -PYQWEYPYLL-SLVPSFIGALAMPKNNISYLVISMISAGLFSVAPLIFGAMEMFPLAQQLYRHGKaYR-FIFGFSAVSV 147 zebrafish
XP_018655169  79 -GELWEYVWFFgSIFPTLFGYISLQRSRAGLMRVSLTGTVVFGLGTVAVGCFTNAFELMTYYQSRVaKH-YFYEFPVIVL 156
XP_002127629  72 -VEVWQYVYML-APFITFIGYSSLHKNKATQMSIYIYFSLATLVPALLY---------KAWLNFTNpSQtTLFKMPLSVL 140

6WVD_A       290 MYLVLVLAVQVHAWQLY-YSKKLLDSWFTST 319 synthetic construct
XP_003728147 145 W-VFVLASNAINYLATYvYSIRLKAAWNVRK 174
XP_516267    148 MYLVLVLAVQVHAWQLY-YSKKLLDSWFTST 177
XP_027284898 148 MYLVLILAVQVHAWQLY-YSKKLLDSWFTST 177
XP_005995812 148 MYLILVIAVQVHGWQVY-YSKKLLDSWFTST 177
XP_005807878 148 MYLVIVIAVQVHAWQIY-YSKQLLDQWFTAT 177
XP_003961803 147 MYVVMVIAVQVHAWQLY-YMKKLLDSWFNTT 176
Q5XJX0       148 MYLLMVIAIQVHAWQIY-YSKKLLDAWFNST 177 zebrafish
XP_018655169 157 AYIFFSLCVQVHGFSVY-FGYKLYCIWSVKV 186
XP_002127629 141 NYIFVVLTILMHAYSLF-CASKLVKAWKQKG 170
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