Conserved Protein Domain Family
Involucrin2

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pfam06994: Involucrin2 
Involucrin
This family represents a conserved region approximately 60 residues long, multiple copies of which are found within eukaryotic involucrin, and which is rich in glutamine and glutamic acid residues. Involucrin forms part of the insoluble cornified cell envelope (a specialized protective barrier) of stratified squamous epithelia. Members of this family seem to be restricted to mammals.
Statistics
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PSSM-Id: 399762
View PSSM: pfam06994
Aligned: 17 rows
Threshold Bit Score: 28.6074
Threshold Setting Gi: 11559966
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
NP_999613     82 EPQQQELHVEQQQ-Q--------QQESQV----QELHVDQQQqqqESQEQELHVDQ 124 pig
EHB13102      59 EPQEEELYLRQQQ-H--------PQKPPE----PELHLGKQQ---EPQEPE-QPPE 97  naked mole-rat
P48997       310 KLHKPELYLRKQQ-Y--------QE-SPD----PELSLGKQQh-qECQEPELQLEE 350 house mouse
XP_006501110 173 mLVPQELHLRQHQ-----------EKLQD----PELHLGQQQk--TPEEQKLIPGE 211 house mouse
P48997       153 ETQEQGLCLGQKQ----------QQQQQDmlvpQELHLRQHQe--KLQDPELHLGQ 196 house mouse
EGW13874     188 tPEEQELIPGEKQ-----------QKLQK----QELH--QEQrhqEPQKPELQLAQ 226 Chinese hamster
XP_003803978 175 ESQEQGLCLIKQR-E--------PQESQE----QRLHLGKEQ---ESQEQRLHLGK 214 small-eared galago
NP_999613    257 ESQEQELHVDQHQ-Q--------QQESQE----QELHVDQQQq--ELQVQEV---Q 294 pig
XP_008262643 118 EPQVQEVHVGQQQpQvqevhvgqQPEPQV----QEVHVGQQP---EPQVQEVHVGQ 166 rabbit
XP_006232869 155 vlAPQELHMGQHQ----------KEKLQE----PELPLGQQQk--TPEEQELILGE 194 Norway rat
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