6DCB


Conserved Protein Domain Family
Bin3

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pfam06859: Bin3 
Bicoid-interacting protein 3 (Bin3)
This family represents a conserved region of approximately 120 residues within eukaryotic Bicoid-interacting protein 3 (Bin3). Bin3, which shows similarity to a number of protein methyltransferases that modify RNA-binding proteins, interacts with Bicoid, which itself directs pattern formation in the early Drosophila embryo. The interaction might allow Bicoid to switch between its dual roles in transcription and translation. Note that family members contain a conserved HLN motif.
Statistics
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PSSM-Id: 399683
View PSSM: pfam06859
Aligned: 76 rows
Threshold Bit Score: 94.135
Threshold Setting Gi: 512909855
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6DCB_A       195 YDVVLCLSLTKWVHLNWGDEGLKRMFRRIYRHLRPGGILVLEPQPWSSYG---KRKTL--TETIYKN----YYR----IQ 261
XP_004927023 132 FDITFCFSVSMWIHLNNGDNGLREFLEHIKTISKS---IIIEPQPWKCYR---QAQKR---IKKTGNtfqlYDT----LK 198 domestic silkworm
EFA03973     126 FDAVFCFSITMWIHLNYGDDGLIRFLNEICDLGDF---VIIEPQPWKCYRsavKRLKL--SDATFPL----FKE----LQ 192 red flour beetle
XP_005986220 160 FDICFCMSVTMWIHLNHGDCGLLGFLSSIAGLTQF---LLIEPQPWKCYR---SAARR--LRKLGRNdfdhFKK----LE 227 coelacanth
XP_002404435 131 FDITFCFSVTMWIHLNHGDEGLKSFLVSVCANTRY---LLLEAQLWKCYR---SASRR--MRRASCDefqhLDT----LR 198 black-legged tick
EDS35689     137 FDMVFCFSVLMYPHLNHGDEGLRSVLDYICSKTKV---LVLELQSWDKYR---DNVRR--LKRDCGEqfplYEK----LE 204 southern house ...
Q7Q3K9       138 FDVICCFSVLMYVHLNGGDAGLRRVLDYLCSKGKF---LIIELQSWQKYR---DQVRR--LKRDAGEtypqYTG----LQ 205 Anopheles gambi...
XP_013020967 146 FHTVLALSVTKWIHLNGLDEGLLSFFKKMHAVLEPDGVLIIEPQSWDSYLkaaKKFLF-------------FEKslhkIQ 212 Schizosaccharom...
Q9Y7L2       147 FKIILALSVSKWVHLNNHDEGIIKFFGKISSLLETNGVLILEPQGWDSYLkaaKKISV-------------FNQtpenLK 213 Schizosaccharom...
Q8IHR1       265 YDIILAFSVIKWIHLNNGDEHLILFFDRVYFMLRKNGYFILEYNKEKKYKl-rKIQKKyyKKNISLN----YTHfddiAQ 339 Plasmodium falc...
6DCB_A       262 LKPE------QFSSYLTSpDVGFSSYELVAtPHNTsk-----gF-QRPVYLFHK 303
XP_004927023 199 IRSQvd---iFIESILKE-HTHIKVYESQNsS-----------W-NRKIQSYKl 236 domestic silkworm
EFA03973     193 ITHD-------VENKIEQ--HILTSCKAVKlYESErs-----eW-GRKLQIF-K 230 red flour beetle
XP_005986220 228 IKGDvt---eKIREYLLA-DCSMELVTCFGsTN----------W-DRSLLLFkr 266 coelacanth
XP_002404435 199 MNINve---eNIHSFLLG-RCCMELVQCFGqTQ----------W-DRKVTLYrk 237 black-legged tick
EDS35689     205 WRGNqgkleqNIYEYVEK--LGFERKSEEFdKNE---------Y-KRNIVIYss 246 southern house mosquito
Q7Q3K9       206 WRGNggalegCITSYVQS--NGMELVAESAeKTE---------F-DRQLIFFK- 246 Anopheles gambiae str. PEST
XP_013020967 213 IRPE------NFPEILEQ--HGFDLQTVVSsENARpknieqrgFsKRDIFIFRK 258 Schizosaccharomyces cryophilus OY26
Q9Y7L2       214 IQPD------AFEHLLNQ--AGLVLEYSIEpQVNNsey---knFaKRTMYIYKK 256 Schizosaccharomyces pombe 972h-
Q8IHR1       340 GKYN------NNSRMVLVnKFFFFTNKGDErSKNKnkl---gmF-NREICIYQK 383 Plasmodium falciparum 3D7
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