5VJ1


Conserved Protein Domain Family
MdcE
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pfam06833: MdcE (488591 is an unknown moldel)
Malonate decarboxylase gamma subunit
This family consists of several bacterial malonate decarboxylase gamma subunit proteins. Malonate decarboxylase of Klebsiella pneumoniae consists of four different subunits and catalyses the conversion of malonate plus H+ to acetate and CO2. The catalysis proceeds via acetyl and malonyl thioester residues with the phosphribosyl-dephospho-CoA prosthetic group of the acyl carrier protein (ACP) subunit. MdcD and E together probably function as malonyl-S-ACP decarboxylase.
Links
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Statistics
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PSSM-Id: 488591
Aligned: 5 rows
Threshold Bit Score: 236.28
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5VJ1_E  74 ARQGEVGLLEGWGLAAAVDEALEADREAPrkraLLAIVDVPSQAYGRREEALGIHQALAGAVDAYARARLAGHPLIGLLV 153 Pseudomonas aeruginosa
Q89UY5  42 TQGQPLGVDEAIALAGRVIEIIKSNDRAP----ILVLVDSASQRMSKRDELLGLSEYLSHLAKALLLAEAEGHRTVGLLY 117 Bradyrhizobium japonicum
Q89XP1  42 ANRTALGVDEAIRLSAHVLKSI-GRDSGP----ILVLVDSDSQRMSKRDELLGLNEFLAHLAKVLIHADMNGRPTIGVLY 116 Bradyrhizobium japonicum
Q8P4U4  41 ANKLEVGVDHALALAATVLASTRTHPQRP----IVMLADTAGQRLARGDELLGINGYFAHLAKSLDLARARGARLVTLVY 116 Xanthomonas campestri...
Q87V58  56 ARQGEVGLLEGWGLAKAVDDAIEQDRERAekraLIAIVDVPSQAYGRREEALGIHQALAGAVDSYARARLAGHPVIGLLV 135 Pseudomonas syringae ...

5VJ1_E 154 GKAMSGAFLAHGYQANRLIALhdPGVMVHAMGKAAAARITLRSVEELEALAAKVPPMAYDIDSYASLGLLWRTLPvetve 233 Pseudomonas aeruginosa
Q89UY5 118 GGSAAGAFIATALATGTLVAL--PGAHPAVMDLPSMARVTKLPIEVLKAKAEATPVFAPGLDNMVRTGGIHVVWD----- 190 Bradyrhizobium japonicum
Q89XP1 117 GHSAAGALLATGLATRVLVGL--PGADPAVMDLPSMAKVTKLSMEALQEKAKSTPVFAPGLSNLAQMGAVHMTWS----- 189 Bradyrhizobium japonicum
Q8P4U4 117 GESVSGGFLSFGLMADHIHAL--PDAQIRVMDLRAMARVTKQTVDTLQALSKSSPVFAPGVENYVRMGAVESLWD----- 189 Xanthomonas campestri...
Q87V58 136 GKAMSGAFLAHGYQANRLIALrdPGVMVHAMGKASAARVTQRSVDDLEKLAASIAPMAYDIDSYASLGLLWETLSvsqie 215 Pseudomonas syringae ...

5VJ1_E 234 vpstaDLVRVRTCLGEALADilGGPRDLGGRLGAA--NREASARVRRLLREQW 284 Pseudomonas aeruginosa
Q89UY5 191 -----ETAPLAPQLAAVLAQ--PAGRDERSRLGAErgGRRKAAEIADRVVALA 236 Bradyrhizobium japonicum
Q89XP1 190 -----NAASLADQLEALLADm-PAAQDRRDALGKQrgGRLKAAEIAERVRDLA 236 Bradyrhizobium japonicum
Q8P4U4 190 -------GDLAQALLDALAT--PSTGDQRRTLGAErgGRTLARDVSAAVAAGE 233 Xanthomonas campestris pv. campestris
Q87V58 216 qpavdDLTQVRQVLSSAIKDvqASGVDLSSRLGAS--NRKASAHVRQLLRAQW 266 Pseudomonas syringae pv. tomato
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