3I08


Conserved Protein Domain Family
NOD
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pfam06816: NOD (This model is not part of the current CDD release)
NOTCH protein
NOTCH signalling plays a fundamental role during a great number of developmental processes in multicellular animals. NOD and NODP represent a region present in many NOTCH proteins and NOTCH homologs in multiple species such as NOTCH2 and NOTCH3, LIN12, SC1 and TAN1. Role of NOD domain remains to be elucidated.
Links
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Statistics
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PSSM-Id: 517431
Aligned: 42 rows
Threshold Bit Score: 63.687
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3I08_A         122 PERLAAGTLVVVVLMPPEQLRNSSFHFLRELSRVLHTNVVFKRDAHGQQMIFPYYG 177  human
P14585         753 TNATIITNIRITVQMDPKEFQVTGGQSLMEISSALRVTVRIQRDEEG-PLVFQWNG 807  Caenorhabditis elegans
2_pfamImport     1 KNTTVLTNIRIKIQMEPREFQATGGQTLMEISSALRAAVRIQKDEEG-PLVFEWMG 55  
1_pfamImport     1 TEVTILTDIRLKIQIDPVEFQSSGGQTLMEISTALRATVRIQRDEEG-PLVFEWDG 55  
XP_045093315   665 TGAMILNDIRIVIQIDPLVFRETGGETLMEISTQLRAAVRIQKDESG-PLVFKWDG 719 
4_pfamImport     1 PPELAEGVISMIILMDMQGFRKNLVAFLRDTSHQLRTNVRVKKDQEGRDMIYPWLG 56  
EFX69806       165 PSILALGSVSMVLEMDLPTFKNMSVAFVRSIGRQLRTTVRIKLDQQGYEMVYPWNL 220 
EFN60549        65 PPSLAKGAISIVVRMDMESFREHIVTFLRELGNELRTTTRVKQDELGNDMIYPWKP 120 
XP_002425606  1556 QPTLATGMISVIVLMDMQTFRSNIRPFLREIGIQLRTSVRVKQDLLGNERIYPWKP 1611
20_pfamImport    1 PPRLAQGAISVVVLMDMQMFNANLVKFLRDIGHHLRATVRVKTEGDGRDMVYPWKV 56
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