6RIU


Conserved Protein Domain Family
ImpA_N

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pfam06812: ImpA_N 
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ImpA, N-terminal, type VI secretion system
This family represents a conserved region located towards the N-terminal end of ImpA and related proteins. ImpA is an inner membrane protein, which has been suggested to be involved with proteins that are exported and associated with colony variations in Actinobacillus actinomycetemcomitans. The ImpA gene in Vibrio cholera and many other bacteria is expressed from the virulence factor operon which produces the pathogenic injection, type VI secretion system; although the exact function of this gene-product is not known it appears to be an essential component of the pathogenic effect.
Statistics
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PSSM-Id: 429132
Aligned: 114 rows
Threshold Bit Score: 44.9166
Threshold Setting Gi: 530328607
Created: 27-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6RIU_A          12 KPISSSNPVGERLVDHPLFDFIEDQMMKVg---------sLSHASVQWDEVEHSTLKLLGEQSKDIKLLVYLLQCLHNQV 82  
Q3IWK5           9 DPIEGDAPSGADLRNDPRFHAIERLIEPArraarqaaaetGSQVQLDWSAIVAEARALA-ASGRDLRLLVILLRALTAEE 87  Rhodobacter s...
Q88FL7          17 APIDAQVPAGLFDGEDETYQAIDQEMVKLg---------gLQEASIDWDYIEEASAQYLERQCKHLRIVAHLSVAWLRSG 87  Pseudomonas p...
WP_015465498    12 KPIRAKCAVGERLLDDPLLDFVETQMIKVg---------sLSHGEVQWDEIEKICMNLLENKTKDLKILTYLLQCMQYQA 82  Psychromonas ...
CCO60168        12 APISEESPVGERVVDDPVFDFVESQMMKVg---------sLSHAEVRWAEVETGIISLFEQKTKDLKLMTHLLQCFHHSN 82  Vibrio nigrip...
Q9KN46          12 KPISSSNPVGERLVDHPLFDFIEDQMMKVg---------sLSHASVQWDEVEHSTLKLLGEQSKDIKLLVYLLQCLHNQV 82  Vibrio cholerae
WP_013332667    14 aPLAEG--VGEPVTSHEDYDWLDEEMMKVg---------sLQHGEVDWAGAETRAARLLAEHGKDLKVLGHLLHCLQHDA 82  Halomonas elo...
Q0ACM4          21 APLSADRVAGQPVAEDPDYAWLDEELIKVg---------sLQHGGIDWAGAERRAIRLLSGLGKDLRVLAHLLHCLQREG 91  Alkalilimnico...
Q6D1L3          12 tSLPDERLRAAVLADDPLWEKVETELVKLg---------sLAHNQVDLNVVAGYCLTLLESKTKDMRVLVQLLRCLQHPA 82  Pectobacteriu...
jgi:Arnit_1741   7 NQINSSLICGQDCKYDDSFLLIEQEIDKTys--------vNQEEETNWEYVVENCEKILLEKSKDIKVSSWYLYGLIKQN 78  Arcobacter ni...
6RIU_A          83 TPTRLITSFAVMSEFLNQYWNDSYPAPGARGNL----PRRKFFSQMA 125 
Q3IWK5          88 GLAGLASGLDLLARTVESYWDTLHPALREGPPQeaamRRVNALRQIE 134 Rhodobacter sphaeroides 2.4.1
Q88FL7          88 CWERWGFTLALLGGMIDNYWETAHPTPGPKGFL----TKRKIVGLlf 130 Pseudomonas putida KT2440
WP_015465498    83 SAERFTLSVYILIDFMTAFWETCYPAPGDRGAL----PRRKFFSQIA 125 Psychromonas sp. CNPT3
CCO60168        83 TVDRFCLSMQVVTDFMATYWETCYPAPGARGVL----PRRKFYSQII 125 Vibrio nigripulchritudo
Q9KN46          83 TPTRLITSFAVMSEFLNQYWNDSYPAPGPRGNL----PRRKFFSQMA 125 Vibrio cholerae
WP_013332667    83 DPVRFALSLELLVGALDGWWVEAYPFAGPRGKR----ARPKLFQQFA 125 Halomonas elongata
Q0ACM4          92 DATRFELALLLLQRCLGTWWSEAHPAPGDRGSR----WRTRLFSTIV 134 Alkalilimnicola ehrlichii MLHE-1
Q6D1L3          83 KATPFSTALMLLDSWLESYWVTAWPASp--------vQKQKLMIQIV 121 Pectobacterium atrosepticum
jgi:Arnit_1741  79 SFNNFENSLRIYIKLLETFSTQMHPKSl--------kAKRNIFLWLE 117 Arcobacter nitrofigilis DSM 7299
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