Conserved Protein Domain Family
MINAR1_C
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pfam06789: MINAR1_C 
MINAR1 C-terminal domain
Major intrinsically disordered Notch2-associated receptor 1 (MINAR1) is a Notch2-binding protein that has been shown to inhibit angiogenesis and breast cancer growth. This entry represents the C terminus of the MINAR1 protein.
Links
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Statistics
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PSSM-Id: 488564
Aligned: 5 rows
Threshold Bit Score: 207.458
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_007237291 741 ERHRK---SKETDRQYDAHQAHRSSKPPkdsYLVEQVFSPHHFPPSVKSHVKGSPLYTDLRLAGVPDG-KRPQPSWTIEE 816
1_pfamImport   1 KWHNKvysQREKKRITDTPTTEVSESGP---LPFDKSLSKHITPVTLTSKIKRNPLYSNIRIVDGWEE-KTPNPSWTIQE 76 
Q8K3V7       760 DWHRK---SKEADRQYDIPPQHRLPKQPkdgFLVEQVFSPHPYPTSLKGHMKSNPLYTDMRLTELAEV-KRGQPSWTIEE 835 house mouse
2_pfamImport   1 RWQNRvylQ----VWNNRATITLQHGSPv--VLVDRYLEKHITPVTLKYNIKRNPLYMDLKSIDTVDSgGRFKPSWTIKE 74 
3_pfamImport   1 QWQNRvylQREKRNLNDSYGWKSTEGSP---VLVDKSLGKHITPVTLKSKIKRNPLYSDIRTVDGWES-KKTQPSWTIQE 76 

XP_007237291 817 FKRNS--GDKSK-LSALD------------------LQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIG 875
1_pfamImport  77 YDRHSvhHNLANyLKVRHmfyikcfagpalpqsplpLNRVSKEDPNDLKFWLEDIYTPGYDSLLKKKENEMKKSKLCKIT 156
Q8K3V7       836 YARNS--GDKGK-LTALD------------------LQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIA 894 house mouse
2_pfamImport  75 YDTKTihGNL-DyLK-------------------------------ELDFWLEDLYTPGFDSLLKRKEAEHKRKRLSKIV 122
3_pfamImport  77 YDRHSlhSNLAGyLK-------------------------HSEDPSNLSFWMEDLYTPGYDSLLKKKENELKRNKICKII 131

XP_007237291 876 ALIAAAACTVILVIVVPICTM 896
1_pfamImport 157 LLVLFTICGLVVVIIVPVLVT 177
Q8K3V7       895 ALITAAACTVILVIVVPICTM 915 house mouse
2_pfamImport 123 LSIILLICASLIVIIVPIVVL 143
3_pfamImport 132 TLISVLICIFIVIVTVPIVVT 152
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