Conserved Protein Domain Family
IalB

?
pfam06776: IalB 
Invasion associated locus B (IalB) protein
This family consists of several invasion associated locus B (IalB) proteins and related sequences. IalB is known to be a major virulence factor in Bartonella bacilliformis where it was shown to have a direct role in human erythrocyte parasitism. IalB is upregulated in response to environmental cues signaling vector-to-host transmission. Such environmental cues would include, but not be limited to, temperature, pH, oxidative stress, and haemin limitation. It is also thought that IalB would aide B. bacilliformis survival under stress-inducing environmental conditions. The role of this protein in other bacterial species is unknown.
Statistics
?
PSSM-Id: 399629
View PSSM: pfam06776
Aligned: 37 rows
Threshold Bit Score: 108.551
Threshold Setting Gi: 81635202
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
WP_010972903   41 HGSWQLACAAAAKkdSADaasstggetkpPCAIAQVQLEEkTRKLVVSVEFRLDDAatpDRLNGTMVLPFGLAVTKLFSV 120 Agrobacterium ...
jgi:Mmc1_0778  47 YKDWLLQCFEVPVagQKAe---------eRCTLTQNVGTQ-KVKRIASLSLIKGGEg-rKESFLRLILPLEMYLGEKVTM 115 Magnetococcus ...
jgi:Mmc1_3104  94 FDAWQVICLEEPSarKR------------LCTVQIVATTAeGNRPIFALRVIHRPD---GKRLLGMAFPLGINVQAQNGF 158 Magnetococcus ...
Q15MX5         26 FGSWSLLCGEHG-----------------NCSVSQLVAMDpEGTKVLLGANINFSMs-nSFPVLMLRMPPNLNKSSGVGI 87  Pseudoalteromo...
Q92SE4         57 FGNWTLICDENFKtkQK------------ICNITQNVADE-SGKSIFSWSLAATAE---GRPMMILRVPPAAGKGSRVSL 120 Sinorhizobium ...
WP_012335957   74 QTEWTKVCGKDQGsnAE------------VCYTTRDFVSE-QGQPVLAAAIYDLKGaqgNVRVARFLLPLGLLLQPGILF 140 unclassified M...
Q89PL1         50 YGDWRKLCFKPGG--AKT-----------VCRTSITGTFD-TGQTAVRLDLIEREGd--RTARLQMFVPVGMFVQVPVKL 113 Bradyrhizobium...
CAL77547       81 YAPWTKFCLKGQDanAKQ-----------VCFIGKDGRIE-SGQPVVAAVIIEPEGe--PKKILRVTLPLGMQLQPGTRI 146 Bradyrhizobium...
jgi:Xaut_3868  83 ASPWQKICQEIPE--RKKq----------VCVLTQVLGVE--NQAIAKVDIVEMQDe--PKKRINVSVPLGMRLQPGLRI 146 Xanthobacter a...
Q11KT7         11 YEAWTVQSVKAGEgaRR------------MCRMSQELIQPeTRQRVLLFAITKGEQ---EGPNATLVMPFGLLLSEGFRI 75  Chelativorans ...
WP_010972903  121 KSGNMR-LQE--VQVSTCLP-----VGCIVSFT-PFIELVSALKAEQTLTIEAPDLQGRI-VSFQLQG----KGFPEALK 186 Agrobacterium ...
jgi:Mmc1_0778 116 VVDEES-AKPeiLEWLTCVT-----DGCLAELK-MTKPLLQKLEKGTALNFNASLYNGRRkLAMKFSL----LGFTDGNK 184 Magnetococcus ...
jgi:Mmc1_3104 159 IVDKKK-EWSwaVPITHCLP-----DGCHVLLA-WDEKMEEAFRKGIDGLLVMVRYPKDQ-LNIPFPL----KGFSKAMK 226 Magnetococcus ...
Q15MX5         88 KIDDNN-AIQ--VALSQCTS-----VACQSVIK-IDKTLFAEMRGGRVAKVAFALEKSKQ-LTLPLSL----EGFADAYA 153 Pseudoalteromo...
Q92SE4        121 SFPDRKkPVE--VEVESCDR-----GVCLATVP-VGPILRDNIAREATVGVSYGTGDG-T-ISINLPL----KGLNPALE 186 Sinorhizobium ...
WP_012335957  141 SVDQGQ-STP--GKYAVCFP-----NGCFAEVAgLKDDLIAALKKGTTLNLTVQNQAQRP-VTFAVPL----AGFGKAFD 207 unclassified M...
Q89PL1        114 TVDKGN-TYA--VPYTWCLN-----NACIAADV-AKPGLIREMETGNTLALEVVDPNMLS-VTASLPL----AQFASAHK 179 Bradyrhizobium...
CAL77547      147 VVDSNQ-ALQ--SPYVICFQ-----NGCMSDYE-ATADFLGSLKKGQTLYVQAINSNGTA-LTLPLPLqegnSSFAKAYD 216 Bradyrhizobium...
jgi:Xaut_3868 147 TLD--KdPVN--IPFVLCQPiqgggATCVGDLE-VDGSFIAKFRKANAVYLQMVNGTGRT-LSLPISN----ADFGKAYD 216 Xanthobacter a...
Q11KT7         76 EIAGQE-ILR--GAYRTCLP-----DGCVAEID-LADAALEALESAAAASVLMTANNGQP-VRADISL----RGFKPAYR 141 Chelativorans ...
WP_010972903  187 RLG 189 Agrobacterium tumefaciens complex
jgi:Mmc1_0778 185 QVQ 187 Magnetococcus marinus MC-1
jgi:Mmc1_3104 227 LMD 229 Magnetococcus marinus MC-1
Q15MX5        154 ALL 156 Pseudoalteromonas atlantica T6c
Q92SE4        187 AIE 189 Sinorhizobium meliloti
WP_012335957  208 GPP 210 unclassified Methylobacterium
Q89PL1        180 GPP 182 Bradyrhizobium japonicum
CAL77547      217 GPp 219 Bradyrhizobium sp. ORS 278
jgi:Xaut_3868 217 GAG 219 Xanthobacter autotrophicus Py2
Q11KT7        142 RLT 144 Chelativorans sp. BNC1
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap