6HCZ,6HCZ


Conserved Protein Domain Family
Auto_anti-p27
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pfam06677: Auto_anti-p27 (This model is not part of the current CDD release)
Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)
This family consists of several Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) sequences. It is thought that the potential association of anti-p27 with anti-centromere antibodies suggests that autoantigen p27 might play a role in mitosis.
Links
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Statistics
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PSSM-Id: 517371
Aligned: 97 rows
Threshold Bit Score: 40.1387
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6HCZ_A         37 LMGDYLLRGYRMLGETCAD--C-GTILLQD-KqRKIYCVACQ 74  human
XP_006676878  142 LIGQKMLQGWTLLQNVCRS--CpGIPLVRNrQn-QTLCVICE 180
XP_020431798    9 LIGQKMLLGWTLLDVVCSK--CsVVPLVEDkKnNVILCMGCn 48 
Q55D07         12 LLGKKLLMGWSMLNNVCKD--CkIVPLVENkKdNIILCVSCE 51  Dictyostelium discoideum AX4
EPB86871      123 LIGQKMLQRWALLNEHCPNptCyAVPLIRNpDtKQMFCVICE 164
XP_002953821  175 LLAAKMLQGWALLDKHCPR--C-NTVLVRSkvnKRMFCVACD 213
XP_067743783   18 LLGEKMLQGWTMLGASCPVedC-YTPLMRNkQg-KMFCVRCE 57 
16_pfamImport   2 VLGERMLQGWTMLGVSCPVeeC-YTPLVCNrQsNKMFCVRCD 42 
XP_001415900  133 RVAEKMLMGWTLTNDVCPVssC-SAPLVRNrAg-ESFCVRHE 172
XP_001347352   18 iIGDRLLQGWTLLNATCHM--CnITPLIKQkNkEDRYCARCD 57  Plasmodium falciparum 3D7
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