Conserved Protein Domain Family
MipA

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pfam06629: MipA 
MltA-interacting protein MipA
This family consists of several bacterial MltA-interacting protein (MipA) like sequences. As well as interacting with the membrane-bound lytic transglycosylase MltA, MipA is known to bind to PBP1B, a bifunctional murein transglycosylase/transpeptidase. MipA is considered to be a structural protein mediating the assembly of MltA to PBP1B into a complex.
Statistics
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PSSM-Id: 399552
Aligned: 186 rows
Threshold Bit Score: 93.2253
Threshold Setting Gi: 218322783
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
tigr:CJA_0035   42 LGIGLGVRTNpL---EDgd-dIPLVLLPMVSYTGERFFIDNL----D------F-G-YTLWESDtqq-----lnlLLTPS 100 Cellvibrio ja...
WP_015422743    30 VGASVLYQEQaY---RGtktsDKFMPVPMVNYEGKNFYFHTL----A------T-G-YYLW-NDkk--------dqLSVD 85  Morganella mo...
utah:Sant_1812  42 LGVSAVYATSpY---RGd--dDKVLPFPQINYDSQYVYVKGL----S------A-G-YYLW-KDpq--------nqLSIT 95  Sodalis praec...
AHG20383        19 IGGGMVAEQLaY---RDy--dAQFMPIPIVTYQGERFFISGQ----G------A-G-IHMF-NTdt--------hsVDFT 72  Chania multit...
WP_014205385    30 VGVAAAYSPAvY---KDt--sSNRTVIPVIGYEGEHLFLRGF----T------A-G-YRLMPMGse--------qnIVFR 84  Vibrio furnissii
Q5E4B9          51 LGAAAAYSPSfY---KEt--pSNATIIPMVGYEGEHLFLRGF----S------G-G-YRLKPVGsp--------qnIIFR 105 Aliivibrio fi...
WP_012603587    30 LGVAASYSPAvY---KEt--pSNRTVIPMIGYEGEHFFMRGF----S------A-G-YRLLPAGsp--------qnIVFR 84  Vibrio tasman...
Q7MFK1          33 VGAGVTYGESaFs-tDG----AKAGIEPSLFYNGKYGFIDGSlanySltpwlgLsGnLRFAEVSd--------------- 92  Vibrio vulnif...
Q4FR54          50 VGVNVMAVNSaYdleES----TEIKVLPGVFYDNNRVYARG-----T------QaG-VYLINDG---------------- 97  Psychrobacter...
WP_003659887    33 LGVNATYNATaYhakDP------VFIMPQAFYDNNRWYIEGae-----------aGfYPYKDNKhhvrigltydgQs--- 92  Moraxella cat...
tigr:CJA_0035  101 YDQVfferwdpvnfvlespglgtalngggknssdpkepyplidpgvsGSGDFEGP-----ESLQRKLPkrhm----sglA 171 Cellvibrio ja...
WP_015422743    86 LFYYpqayr----------------------------------akdnkDSRMRKL-----DNRRDTAM-----------A 115 Morganella mo...
utah:Sant_1812  96 AVYApwhfr----------------------------------pskndYDDMKAL-----DKRRSTVM-----------A 125 Sodalis praec...
AHG20383        73 VSYSslsfk----------------------------------psdsdDLAMKKL-----DKRRATAM-----------A 102 Chania multit...
WP_014205385    85 LAYDprtlk----------------------------------pedsdDPQIRLL-----DKRKSTVL-----------G 114 Vibrio furnissii
Q5E4B9         106 FVYDprtfk----------------------------------pndsnDAAMQKL-----DERKSTVL-----------G 135 Aliivibrio fi...
WP_012603587    85 AVYDprtlk----------------------------------psdsdNADIQKL-----DERKASVL-----------G 114 Vibrio tasman...
Q7MFK1          93 ----------------------------------------------dFDDIPRGI-----KNRDGNAD-----------L 110 Vibrio vulnif...
Q4FR54          98 ------------------------------------------------------S-----NQLAAYTQlagnsfepddaT 118 Psychrobacter...
WP_003659887    93 ----------------------------------------------fDPNHANAIelkqlNKRQWSALahasylyitpyG 126 Moraxella cat...
tigr:CJA_0035  172 GLEYHFR-LGGYG-LHLHW-------------LKDVTDIHQG-EERRLA----LSRAWQA----------GnHDLALSAG 221 Cellvibrio ja...
WP_015422743   116 GLSYRHH-EEWGT-LRTNF-------------SGDILGKSDG-MRFDAA----YLYGFEG----------DkWSVQPGVG 165 Morganella mo...
utah:Sant_1812 126 GLRYSHT-ADWGV-VRAEY-------------LGDILDNSDG-FTADLS----YLYPIQQ----------GrFTLVPGIG 175 Sodalis praec...
AHG20383       103 GVEYQYH-AGWGT-VSGEV-------------ATDILGYSNG-VVIDVG----YQYSFQF----------GkWQWVPSAG 152 Chania multit...
WP_014205385   115 GVSYQLR-TLVGM-WEASV-------------GADVAGRHNG-MYGEIA----WRLPLRF----------SnWGITPAIG 164 Vibrio furnissii
Q5E4B9         136 GMSYQMV-THIGI-IELTG-------------GTDVGRTHNG-LYAEAA----WRLPIRG----------RgWAITPSLG 185 Aliivibrio fi...
WP_012603587   115 GVSYQVI-TLVGM-FEATA-------------GSDLGFRHNG-IYAEAA----WRLPIRR----------NgWAITPSIG 164 Vibrio tasman...
Q7MFK1         111 GITVGTVgARLTYl-------------------qDVTNVHDG-------------YEIQLhlgrafdtpfDqWVLSPYVE 158 Vibrio vulnif...
Q4FR54         119 GALSELDeRKASAaAGLSYtrltpvggfraqyATDILD-RSGgNIARLSylgkISk--------------NkLTVYPSVG 183 Psychrobacter...
WP_003659887   127 GLKAKAAt--------------------------DVLDRHNG-------------QTVTLshls--rfnkDaWTVYPEFG 165 Moraxella cat...
tigr:CJA_0035  222 AVWQDATLTNYYYGVPQGDAy---wASYEAGN---------ALSTQ-VRFDWNY--RLSKHWDLRALLSYRRLPEEITAS 286 Cellvibrio ja...
WP_015422743   166 VIWSSEKQNRYEYGITAAESrrsglDEYRPGS---------SWTPY-VEVSGHY--QFDENWSAFAMGRIDLLPSEAKDS 233 Morganella mo...
utah:Sant_1812 176 AMWASEDQNNYYYGVSRSESrrsglREYHADD---------GWSPY-VELTVNY--AITQSWRTYVMARYLRMSDEAKDS 243 Sodalis praec...
AHG20383       153 IKWQSRSFNDYYFGINQQEAqrsnlHEYQAKS---------DISSY-LSLSSYY--AINDNWQLFLSGHYEQMSDAVKDS 220 Chania multit...
WP_014205385   165 YSYNSDKLNNHLYGVSASESarsglQEYDAGW---------DGQYF-IGASAYW--SITRSVRVNGGIRYSNLHSDLSDS 232 Vibrio furnissii
Q5E4B9         186 YSYNSEKLNNHLYGVSNEEAlrtgvDQFNADW---------DGQFF-IGLSTYF--HITPNVRVTGGLRYVNLEGNLENS 253 Aliivibrio fi...
WP_012603587   165 YSYNSKRLNNHLYGVSSSEAartnlDEFDADW---------DGQYF-IGLGGYL--HVTPNVRVTGGVRYTNLEGDIENS 232 Vibrio tasman...
Q7MFK1         159 VDYRSKKLSQHLYNVSAQESaasgltQFDADEtwvykagliSLYDItEQ------------WLAIAKVEFEHHD---SNS 223 Vibrio vulnif...
Q4FR54         184 FEYHDNDYNQYYYGVSDTEStrtgvaAYTANS---------SLNPY-INVSANY--DFNKRWAGFANQSLSYLPNEQYDS 251 Psychrobacter...
WP_003659887   166 ATWHSKDYNQYYYGILDAEAlktnhtAYQADS---------GWSPF-VTATVNYqvTPK--VSAFVNQRIEWLSNAQKNS 233 Moraxella cat...
tigr:CJA_0035  287 PLVRSDKVVTAFIGGVYHF 305 Cellvibrio japonicus Ueda107
WP_015422743   234 PMVDKKHTSILWTGVTYTF 252 Morganella morganii
utah:Sant_1812 244 PMTDRQSIGLIGIGTTYSF 262 Sodalis praecaptivus
AHG20383       221 PMTERAYSLSVATGFLYKF 239 Chania multitudinisentens RB-25
WP_014205385   233 PVVGRDTSVMGTLGIAYVF 251 Vibrio furnissii
Q5E4B9         254 PMIEHTTSSTGSVGIVYVF 272 Aliivibrio fischeri ES114
WP_012603587   233 PILESGINMAANVGVAYVF 251 Vibrio tasmaniensis
Q7MFK1         224 PLIQNDLAWQISLGGAYKF 242 Vibrio vulnificus YJ016
Q4FR54         252 PMVDSRTDATTTLGLLYKF 270 Psychrobacter arcticus
WP_003659887   234 PMTDNKIDSKTRLGLNYHF 252 Moraxella catarrhalis
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