Conserved Protein Domain Family
RAMP4

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pfam06624: RAMP4 (This model is not part of the current CDD release)
Ribosome associated membrane protein RAMP4
This family consists of several ribosome associated membrane protein RAMP4 (or SERP1) sequences. Stabilisation of membrane proteins in response to stress involves the concerted action of a rescue unit in the ER membrane comprised of SERP1/RAMP4, other components of the translocon, and molecular chaperones in the ER.
Statistics
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PSSM-Id: 517355
Aligned: 54 rows
Threshold Bit Score: 37.5087
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_009224052    6 EQRRRNAKFQKDQeARRGKSETDIKqraSKElnHKSPISPIWLGLLGFVVFGG--LVFEVF 64 
XP_009152372    6 AQRRANEKHAKTVeKRMGKPETAYKk--KET--KKSPVGIAAVALLIFVVIAP--LLIEQL 60 
XP_049965127    6 QQRRANEKFAKSEaAKRGRGPTVAKp--RQ---SKSPISMGWLVLLAFVVCGG--LILELF 59 
XP_004445202    6 QQRRANERYAKNEtAKRGKPENISKakiK----PKASLSTGWVVVLAFVVCGG--VMFELV 60 
10_pfamImport   5 QQRKRNEKFSKLQnAKRGKANIEVKp--KQE--FKSPLSPLWAGLLSFVVFGG--LLFELI 59 
XP_007295678   54 EQRKRNEKFNKQQdAKRGKPTQEIIk--KQS--FKSPVSPVVLGLLAFVIFGG--LVFELI 108
XP_067511760    6 TIRQKNNLYKNR--AINHKVASKAAeqsKSI--SKTNYSYWIIGLLCFAMFGG--VILQLI 60 
CCA70147        6 EIRRKNEKFAEN--VRSGKTAVQPStreKLQ--KRSPIGYTALSIIIFVVIGG--GVLQLL 60 
XP_006453980    6 ELRRKNEKFAKA--AREGKKPTHASrleKLS--KRSPINLWALGVICFVVIGGgmLVFELV 62 
XP_001829390    6 ELRKRNEKFAKD--VREGKKALHASraeKLA--ARSPVSAWALGIIMFVVFGG--VVFELL 60 
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