Conserved Protein Domain Family
M-inducer_phosp

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pfam06617: M-inducer_phosp 
M-phase inducer phosphatase
This family represents a region within eukaryotic M-phase inducer phosphatases (EC:3.1.3.48), which also contain the pfam00581 domain. These proteins are involved in the control of mitosis.
Statistics
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PSSM-Id: 429035
Aligned: 18 rows
Threshold Bit Score: 245.407
Threshold Setting Gi: 0
Created: 27-Apr-2021
Updated: 29-Sep-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_015199366  98 MDSPaSPLDPAAVEERFEKALLESGAILrDDKIPIRRINSLPVRLLGSSPALK----QKDPDGRSFgifsrGGSES---- 169 spotted gar
3_pfamImport   1 MDSP-SPMDPLDIEEKFEKAILESGKVViDNKCPIRRINSLPLRLLGSSPALK----HSQLNSLGCgifsdQHETF---- 71 
Q28DL0        83 LDSP-IKMDLNDTEETFQKSTQNSDRLG-HTRLPIKRRNSLPQNLLGSSPAFKrn-lSYSLECEvf-------------h 146 tropical clawed...
NP_001186501  83 LPGTpSPSDIRE--ETFEKAILASSRL--NLRLPLRRIHSLPQRLLGSSPALKrs-hSDSTDCNaf------------ql 145 chicken
1_pfamImport   1 LDSP-GPLDSKE-----------------NLGNPLRRIHSLPQKLLGCSPALKrs-hSDSLDHDif------------ql 49 
EDL77098      86 LDSP-GPLDSKE-----------------NLEISLRRINCLPQKLLGCSPALKrs-hSDSLDHDif------------ql 134 Norway rat
XP_007666523 102 LDSP-SQLDPQAQEEAFEKAIQESGRVIrDNKFPIRRIQSLPMRLLGSSPALKnitnARNLPPS-------PVDGPehkq 173 platypus
XP_012395995 115 MDSP-SPVDPQAMDHVFQEAIREAGQVr-EERLPIRRFQSLPSKLLGSSPALRnitnSRDLDAPr------KGKGDvqld 186 Tasmanian devil
NP_001274445  49 MDSP-SPMDPHMAEQTFEQAIQAASRIIrNEQFAIRRFQSMPVRLLGHSPVLRnitnSQAPDGRr------KSEAGsgaa 121 human
P48966       111 MDSP-SPMDPQTAERTFEQAIQAASRVIqKMQFTIK-ASVFASEAAGHSPVLQnitnSQALDSWe------KDEAGyraa 182 Norway rat
XP_015199366 170 SGNRSGKENLHeGVFEFKKPAVPMSRCRLRS-FHSTEAHDPSARRPSS---------------------------APALM 221 spotted gar
3_pfamImport  72 -PAEGNKENVSgSGATWKKKKKKKKKKTLKE-INGGTSRPLRLRRPASylrmqlsspppklsikcfpasclvfsfVPSLF 149
Q28DL0       147 AADLENKEN---EKFQFKIPARPRSRGCFRS-RLHGDGKESLVQRQKS---------------------------APACM 195 tropical clawed...
NP_001186501 146 LEQNENKEN---ESFEFKKPAKPASRGSVHV--HSHDGKSVLGQRQNS---------------------------ALAQG 193 chicken
1_pfamImport  50 IDQDENKEN---EAFEFKKPVRPL-------------AREFFTQRQNS---------------------------APARM 86 
EDL77098     135 IDQDENKEN---EAFEFKKPIRPASRGCLNA-HVHEESKDPFTHRQNS---------------------------APARM 183 Norway rat
XP_007666523 174 ASLWDNKEN---EGFVFKMPTRPTARSRPHA-VDSASRRDAFAQRPNS---------------------------APDLM 222 platypus
XP_012395995 187 TSSGEDKEN---ETFVFKMPSRPAGHSRSAA-AEWASRREAFAQRPNS---------------------------APDLM 235 Tasmanian devil
NP_001274445 122 SSSGEDKEN---DGFVFKMPWKPTHPSSTHAlAEWASRREAFAQRPSS---------------------------APDLM 171 human
P48966       183 SSPGEDKEN---DGYIFKMPQKLPHSSSARAlAEWASRREAFTQRPSS---------------------------APDLM 232 Norway rat
XP_015199366 222 L-SPPPVaRLCSl-EDGSPVVLRRSSLTSSl------dDDSDDGFLDVLDS-DMES-NAEMPLGIASLLTAPLVQ--EKE 289 spotted gar
3_pfamImport 150 L-PPPPKkKWRDvlSNSSPILLRRCSLTSSl------nDEEDCGFLEILDG-DDVN-D--VPPGMESLLTAPLVTpkDPA 218
Q28DL0       196 LsSPRKSeVAAS-----DMVFVRKSSAASTs------tEGSDDGFLDMLDGeDLEN-DTEFPCGVASLWTAPLVM----- 258 tropical clawed...
NP_001186501 194 FpTQEMPtGELE---NYGPAFLQQSSLTSSe-------SEDDDGFLELLDEqDLKN-DEEMPSDVASLWTAPLVT----- 257 chicken
1_pfamImport  87 LsSNERDsSEPG---SLVPLYLPQSPVTATl-------SDEDDGFMDLLDGeNLKN-DEETPSCMASLWTAPLVT----- 150
EDL77098     184 LsSNESDiSESG---NFSPLFTPQSPVKATl-------SDEDDGFIDLLDGeNLKN-DEETPSCMSSLWTAPLVM----- 247 Norway rat
XP_007666523 223 FcSPERSeAEDE---AASPMCLRRCSLTSIl------vDEGDDGFMDILEQ-DLKNdDDDVPFGMESLLTAPLVG----- 287 platypus
XP_012395995 236 CfSPGEReE------NLGPLPLRRFSMNQSsasgddasDDGDDGFMDILED-DLKN-EEEVPPGMESLISAPLVR---KE 304 Tasmanian devil
NP_001274445 172 ClSPDRKm-EVE---ELSPLALGRFSLTPAeg-----dTEEDDGFVDILES-DLKD-DDAVPPGMESLISAPLVK--TLE 238 human
P48966       233 ClTTDGKm-DVE---EASPVA-QSSSLTPVer-----aCEEDDGFVDILES-DLKD-DDMVPAGMENLISAPLVK--KLD 298 Norway rat
XP_015199366 290 EQSldSPIIRC-RPRGLFRSPSLPASAGR---AHLKRPECPRDEHTPVRVKRRRSVAGTvRPEDTEVEEGTPGMsc--rL 363 spotted gar
3_pfamImport 219 QDLdqDQVIRSrRPRGLFRSPSMPSNVIR---PILKRVERANDEETPVKNKRRKSVAGTtMTEELKENFLNIQMgcsmvK 295
Q28DL0       259 -----KSTENC----LEVRPASEPNCTTK---PALKRVERTPDEDAPEKSKRRRSVS----EIAKEELDHDKNS-----R 317 tropical clawed...
NP_001186501 258 -RRpdSRARRC----RLFGSSSLPSGVGR---TTQKRMERSQEESSPGKSKKRKSLPGA-------QSEDSANT-----K 317 chicken
1_pfamImport 151 -RRatNLGTRG----QHCDASSPCSPSIR---PVLKRPERWQEDSPRGNMKRRRSAAGA--------SPQETPE-----I 209
EDL77098     248 -RRptNLADRC----GLFDSPSPCSSTSScstRAVKRADRSHEESPRGTKRRKSSEASP--VKADVPEPTQ--------L 312 Norway rat
XP_007666523 288 --KkeDLVMHS-KCRRLFRSPSMPSSAIR---PILKRLDRPQDRDTPIKTKRRKSIT----SPACEKAEEEPRA-----R 352 platypus
XP_012395995 305 EESeqSLVMHS-KCRRLFRSPSMPNTSIR---PVLKRLERPRDKDTPVKNKRRKSVTIP--TAALEENEEEPKP-----R 373 Tasmanian devil
NP_001274445 239 KEEekDLVMYS-KCQRLFRSPSMPCSVIR---PILKRLERPQDRDTPVQNKRRRSVT----PPEEQQEAEEPKA-----R 305 human
P48966       299 KEEeqDLIMFS-KCQRLFRSPSMPCSVIR---PILKRLERPHDRDVPVLSKRRKSGT----PLEEQQ-LEEPKA-----R 364 Norway rat
XP_015199366 364 VQRSKSFCDQ---DIEK 377 spotted gar
3_pfamImport 296 LARSKSFCHQ---EIER 309
Q28DL0       318 LMRSKSLSSQ---NIES 331 tropical clawed frog
NP_001186501 318 IVKTQSSAA----EIES 330 chicken
1_pfamImport 210 LRHSLALVPSpkgTIEN 226
EDL77098     313 PHQSLSLTSFpkgTIEN 329 Norway rat
XP_007666523 353 ILRSKSLCHD---EIEN 366 platypus
XP_012395995 374 LLRSRSLCHD---EIET 387 Tasmanian devil
NP_001274445 306 VLRSKSLCHD---EIEN 319 human
P48966       365 VFRSKSLCH----EIES 377 Norway rat
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