Conserved Protein Domain Family
Ly-6_related

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pfam06579: Ly-6_related 
Caenorhabditis elegans ly-6-related protein
This family consists of several Caenorhabditis elegans specific ly-6-related HOT and ODR proteins. These proteins are involved in the olfactory system. Odr-2 mutants are known to be defective in the ability to chemotax to odorants that are recognized by the two AWC olfactory neurons. Odr-2 encodes a membrane-associated protein related to the Ly-6 superfamily of GPI-linked signaling proteins.
Statistics
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PSSM-Id: 399524
View PSSM: pfam06579
Aligned: 14 rows
Threshold Bit Score: 127.458
Threshold Setting Gi: 341892471
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
KRZ83429      42 CASYELRAYW-YH--LQAWYNTPKNFTDRCVTMNRRdcQHIALESCP--SQCITLRQQKTIAGHTVGYH---VIRGCLTS 113 Trichinella sp. T8
EFO24039      35 CMSPLYEELF-KDgvMSRYFYEPRNFTSQCNEPMRP--SNIGLVACK--SICLTLTQDFVVMGRNTGKKl--TIRGCAVS 107 eye worm
PDM61878      86 CMSTYYEQLF-NGr-VQNIFNEPKNFTRHCDDPAAP--HLLEAVACR--TICLTITHDLVVFGQRTGQIv--TMRGCAIS 157 Pristionchus pa...
Q8T3D0        43 CASFVYLPLW-SQ--LMHHYYPPKNFTDRCWQPD----SGIGLVPCS--SACFTLVER--IDDVSEQHG---VIRGCMDR 108 Caenorhabditis ...
EGT34036      30 CMSKLYEAVW-PS--LSHIYKKPRNFTDDCDDERISe-GRVPIVHCP--TICVSLFEQPNIAGVRIKG----YIRGCMSD 99  Caenorhabditis ...
NP_001256848  51 CMSLSYQTSW-KY--LQTTYIYPKVFTDRCRDPNSE--RGMPTVMCG--SVCVSLMEPDVEAGVFIGFK---HIRGCLDR 120 Caenorhabditis ...
CDK13497      37 CMSKYYGALW-RFagYTRIYQEPGLFTDSCRDPQARg-SDVPSTICKekTNCVTMVEDLKIGTGAKG-----YIRGCWGS 109 Caenorhabditis ...
CCD83391      30 CMSPYLEDHY-PY--ISHLYRKPLSFDTHCDKHSLEt-SYLYSKNCS--DMCVTLRINDVVGGRRRHG----YMRGCLSD 99  Caenorhabditis ...
CRZ25903      39 CMSEAFQKHW-SF--LSQIYFMPMNFTDYCYDMPPK--VHIGVTTCSh-SLCVTVIEPRILAGHHIGNN---VIRGCFSS 109 Brugia malayi
EGT48406      26 cASFEYRVLFdKDtsLSRKVRVPK-FDRLCDLEEMVq-GFAPVETCH--STCVTIFEPQYFGGLQSLQRpflYIRGCADH 101 Caenorhabditis ...
KRZ83429     114 LFRWNILdtsQISASLMKPRDFCYNLRLS--QILPSYgsgvkGESDQlVRLCVCHGDRCNS 172 Trichinella sp. T8
EFO24039     108 ISRHGFF---NRTMVLFDRYDMCRDVKAS--DLFRYE-----SDSQT-IRVCSCFGDRCNV 157 eye worm
PDM61878     158 IAKKGIH---NHTLAMFDRYDICREMNAA--DLFRTEyg--rGESQR-IKVCSCLGDRcnh 210 Pristionchus pacificus
Q8T3D0       109 LLLFGLDddvRNILSAYENQRVCRHTDRKllRLFPLSgq-------tdVTFCSCNGDFCNe 162 Caenorhabditis elegans
EGT34036     100 VLISGFNqtiVTWYRWMHRDS-CRPYRKK--ELFKLGge--sTDDST-IDVCTCYADHCNG 154 Caenorhabditis brenneri
NP_001256848 121 VLRHGFNqsaLRTHR-FHQNNHCRTLSRS--ALFNPArqtdpPALGD-VQLCSCYGDRCNS 177 Caenorhabditis elegans
CDK13497     110 VFLFGFNr--TGTVGALAEHSFCHTFNLT--QLVSgg----rPEESS-INVCSCRGPLCNG 161 Caenorhabditis elegans
CCD83391     100 L--HGYN---HSLIRTLAERQGCLDTTAR--ELFLPTaqrqeLEPSR-LSLCACHNNLCNF 152 Caenorhabditis elegans
CRZ25903     110 VFKYGPT---PSNDGFSTSDTSCSRMPAY--KLLPPHla-rrASNRT-VELCWCFGQLCNd 163 Brugia malayi
EGT48406     102 IFSEMKNr--PIEVEFLHRSPICVKLQLS--QIYPq------VQANEiVQVCSCDKDGCNF 152 Caenorhabditis brenneri
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