Conserved Protein Domain Family
Vert_IL3-reg_TF

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pfam06529: Vert_IL3-reg_TF 
Vertebrate interleukin-3 regulated transcription factor
This family includes vertebrate transcription factors, some of which are regulated by IL-3/adenovirus E4 promoter binding protein. Others were found to strongly repress transcription in a DNA-binding-site-dependent manner.
Statistics
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PSSM-Id: 368956
View PSSM: pfam06529
Aligned: 14 rows
Threshold Bit Score: 495.109
Threshold Setting Gi: 82198781
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_007255391 116 SSAAYTQeVQKLSTATSTLYQEFVSPG-TAKASYSTELELSRLGSSCISVIKHSPHSALSDGSDSSTG--TQSSPL--MN 190 Mexican tetra
XP_001378261 129 SSTVYAQeIQKLSNSTAVYFQDYQTTK-SNVSSFVDEHEASMVGSSCISVIKHSPQSSLSDVSEVSSGehSQESPV--QN 205 gray short-tail...
Q5FW38       130 SSASYAQeIQKVTTSTAMYFQEYSSSK-PNVMSYNSDHEHSVMTSSCISVIKHSPQSSLSDVSEASSVehVQPSTV--QS 206 tropical clawed...
XP_006005039 125 SSTVYAQeVQKINNSTAMFFQEYSSSN-ANINPFPNDHEHAMLGSSCISVIKHSPPSSLSDASETCSn--ARESPV--QG 199 coelacanth
XP_003216464 130 SSSAYAQeVQKLSNATAVYFQEYQNSK-SSINSFIDEHEPSMVGSTCISVIKHSPQSSLSDVSEVSSVehTHASPI--QN 206 green anole
Q90Z72       130 SSASYAQeIQKLSSSTTVYFQDYQSSK-PNINSFVDEHEPSVVGSSCISVIKHSPQSSMSDMSEMPSVehTQGSRI--QS 206 chicken
XP_003638841 130 SSTAYTQeIQKLSHSTAVYFQDYQASK-ASASPFVDEHEPSMVTSGCISVIKHSPQASLSDVSEVSSLehSQDGAA--RG 206 dog
XP_014302265 130 SSTAYAQeIQKLRNSAAVYFQDYPA---APGGGFADEPA----ASSCISVIRHSPQGARAEGAE-GSLepAREGAVrsQS 201 little brown bat
XP_004870110 130 SSTAYAQeIQKLSNSTAVYFQDYQTAKpTSGNAFGDEHEPGLVSGSCISVIKHSPQSSMSDMSEASSGehAQESPV--QG 207 naked mole-rat
ELV13364     130 SSTAYAQeVQKLSSPPAVYFPDCQPSK-SGVGAFGDEHEPPMAAGSCISVIKHSPQSSLSDASEVSSVdpMQESPV--QG 206 Chinese tree shrew
XP_007255391 191 ICRTPE----IIKQEPVENGSYTRDQAS-----PYELYKNYLNSPFPrGYSQPSPFLQMTRSSSNSPRTSDGDDGTVSKS 261 Mexican tetra
XP_001378261 206 SCRSPQnqfqDIKQEPMELESYPRESREdrssyPASIYPNYLGNTFS-GFTHSPPLLQMNRSSSNSPRTSETDEGAVGKS 284 gray short-tail...
Q5FW38       207 NCRSTDinfqRIKQEPMERENFSRDAREdsntfQGSIYTNYIGNTFS-GYSHSPPLLHINRSSSNSPRTSEADEGVVGKT 285 tropical clawed...
XP_006005039 200 NCRTPEnnftAIKQETMELDSYAREPRDetgsyATAVYKNYVGATFN-NYSHSPHNLQIASSSSNSPRTSETDDGIVGKS 278 coelacanth
XP_003216464 207 NCRDPEnkfqLIKQEPMELENYARDSRDergsyTTSIYQNFMGSNFS-GYSHSPPLLQVNRSSSNSPRTSEADDGVVGKS 285 green anole
Q90Z72       207 NCRSPEnkfqIIKQEPIELE---REPRDdrgsyKASIYPNYMGTTFN-MYSHSPPLLQVNRSSSNSPRTSETDDGVVGKS 282 chicken
XP_003638841 207 GCGSPEgkfqAIKQEPVELESYAREPGDergayRASVYQNLMGTAFP-GYSHSPPLLQVARSSSNSPRTSETDDGAVGKS 285 dog
XP_014302265 202 GCPSPAgklqAIKQEPVELEGYAREPRDdpgayRAAVYQNYVGSSFP-AYSHSPPLLPASRSSSNSPRTSETDDGAVGKS 280 little brown bat
XP_004870110 208 SCRSPEskfqVIKQEPVELETFPREPRDdqgsyTAAIYQSYMGSSFA-SYSHSPPLLQVNRSSSNSPRTSETDDAVVGKS 286 naked mole-rat
ELV13364     207 SCRSPEgkfqAIKQEPVELESYAREPRDdrgpyVASIYQSYMGGAFA-GLAHSPPLLQVSRSSSNSPRTSETDDGVVGKS 285 Chinese tree shrew
XP_007255391 262 SDGedeqQVPKGPAPSTADPKSVIVSALKVPDTNASALPHKLRIKARAIQIKVEAIDPDYDSSGKTSSPIDMSARGCYQM 341 Mexican tetra
XP_001378261 285 SDGedeqQVPKGPIHSPVELKSLHATVVKVPEVN-SALPHKLRIKAKAMQIKVEAFDSEFDGAQKLSSPIDMSSKRHFDL 363 gray short-tail...
Q5FW38       286 SDGedeqQVPKGPIHSPVELKNGHTTIIKVPEVNSSALPHKLRIKAKAMQIKVEALESELNSTQKLTLPIDMSSKRHLQL 365 tropical clawed...
XP_006005039 279 SDGedeqQVPKGPIHSPVEPKSAFMTNVKVPEVNSSALPHKLRIKAKAIQVKMEGAEQDYDTFGKLSSPIDMSTKRHYEH 358 coelacanth
XP_003216464 286 SDGedeqQVPKGPIHSPVELKNTHAT-VKVPEVSSSALPHKLRIKAKAMQIKMESPENEYDATQKLSSPIDMSSKRHFEV 364 green anole
Q90Z72       283 SDGedeqQVPKGPIHSPVEHKNVHAT-VKVPEVNSSALPHKLRIKAKAMQVKVEAMDNDYDATQKLSSPIDMSSKRHFEL 361 chicken
XP_003638841 286 SDGedeqQVPKGPIHSPVELQRVHATVVKVPEANSSALPHKLRIKAKAMQIKVEAFDHEFDATQKPSSPVDGAPKRHFEL 365 dog
XP_014302265 281 SDGedeqQVPKGPIHSPLELQHGHATVVKVPEANSSALPHKLRIKAKAMQIKVEALDTDFEATHKLPSPVGATATRHFGL 360 little brown bat
XP_004870110 287 SDGedeqQVPKGPIHSSVELKCMHTTVVKVPEVNSSALPHKLRIKAKAMQIKVEAFDNEFEATQKLSSPVDMTSKRHFEL 366 naked mole-rat
ELV13364     286 SDGedeqQVPKGPIHSPVELKRVHATVVKVPEVNSSALPHKLRIKAKAMQIKVEAFDHDFDATQKLSSALDMTSKRHLEL 365 Chinese tree shrew
XP_007255391 342 AHAGTPEYTQSSlspLSLQVNSvHDWNHQPEYWH-KDQREALPPSGCKNrLcpdspgpvtkklIVDLKDGCYASSESENL 420 Mexican tetra
XP_001378261 364 EKQDTQSLIHSPltpFSVQVTNiQDWSLKAEPWP-PKELRGSLQKSCSA-G------------GFEIKDGVYAVSDVENL 429 gray short-tail...
Q5FW38       366 EKHNSETMVHSSlspLSVQVTNiQDWPLKPGQWH-HRELD-KIPSVCKTsG------------IVDIKDNVFKASESESL 431 tropical clawed...
XP_006005039 359 EKPNTQNLVNSvt-pLSVQLSNiQDWSHKPGHWSqHEE---KNLNSYKN-G------------HVDEKDNAYIASEAENL 421 coelacanth
XP_003216464 365 EKHNAQNLVQAShtpFSVQVTNiQDWSLKPEHWHnQKELTEKIPSGCKN-A------------IAEVKDNSYKISETENL 431 green anole
Q90Z72       362 EKHGAQNLVHSShtpFSVQVTNiQDWSLKPELWH-QKELNVKIQNGCKT-G------------VVEIKDNVYNVSESENL 427 chicken
XP_003638841 366 EKHPGPGMVHSSltpFSVQVTNiQDWSLKSEHWH-QKELHGKTQNSFKT-G------------VVEMQDSGYKVSDPENL 431 dog
XP_014302265 361 EKPGAPSAGHAPltpFSVQVTNiQDWSLRSEHWH-QKELMGKTQNSFKT-G------------VAEMKDNGYKVCDPESL 426 little brown bat
XP_004870110 367 GKHNAPSMVHSSlppFSVQVTSiQDWSLRSEHWH-PKDLSGKTQSGFKT-G------------VVEIKDNGYKVSDSENL 432 naked mole-rat
ELV13364     366 EKHGAPGLVHSlt-pFSVQVTNiQDWSLKSEHWH-QKELNG------KT-G------------VVDGKDGGYKASEPGHL 424 Chinese tree shrew
XP_007255391 421 YLKRGIADLSAEVASLKRLITTRQGSV 447 Mexican tetra
XP_001378261 430 YLKQGRASFSADVASLKRLITTQHISA 456 gray short-tailed opossum
Q5FW38       432 YLKQGIANLSAEVATLKRLIVTQEICA 458 tropical clawed frog
XP_006005039 422 YLKQGIANLSAEVASLKRLITNQQISA 448 coelacanth
XP_003216464 432 YLKQGIANLSAEVASLKRLITTQHTSP 458 green anole
Q90Z72       428 YLKQGIANLSAEVASLKRLITTQQISA 454 chicken
XP_003638841 432 FLKQGIANLSTEVVSLKRLIATHQISA 458 dog
XP_014302265 427 FLKQGLANLSAEVVSLKRLTATHQISA 453 little brown bat
XP_004870110 433 YVKQGIANLSAEVVSLKRLIATQPISA 459 naked mole-rat
ELV13364     425 YLKPGIANLPAEVVSLKRLIATQPISA 451 Chinese tree shrew
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