4YZ9,4O1O


Conserved Protein Domain Family
Ribonuc_2-5A

?
pfam06479: Ribonuc_2-5A 
Ribonuclease 2-5A
This domain is a endoribonuclease. Specifically it cleaves an intron from Hac1 mRNA in humans, which causes it to be much more efficiently translated.
Statistics
?
PSSM-Id: 399473
View PSSM: pfam06479
Aligned: 159 rows
Threshold Bit Score: 77.9071
Threshold Setting Gi: 74996678
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
4YZ9_A       277 QLQFFQDVSDRIEKESLDGP--IVKQLERGGRAVVKM--DWRENITVPLQTDLRKFR----T-YKGGSVRDLLRAMRNKK 347
ABF55365     591 RYRTLRDVGNESDIKQRLRNsrIVQLLQLENSECSRTfaQWTSKIDKYVMTVMNKFYekkrN-FYEDTPSDLLKFIRNLG 669 dog
XP_005319780 593 RYRALRDVGNENDIKRRKTKseILTRLTPGSSEPPRSfnWWTYKIDKDVMKRMNKFYekngD-FYRDTVGDLLKFIRNMG 671 thirteen-lined ...
NP_001166526 586 RYRTLRNVGNESDIKMRKSDseILNLLQLESSECSRSfaKWTDKIDKSVMKSMNKFYkkkkT-FYQDSVGDLLKFIRNIG 664 domestic guinea...
XP_003264481 592 RYRTLRNVGNESDIKTRKPEseILKLLQPGPSEHSKSfdKWTTKINECVMKEMNKFYkkngN-FYQNTVGDLLKFIRNLG 670 northern white-...
XP_003785845 592 RYRTLRNVGNESDIKTRKPKseILKLLEPETSECPYSfaKWTKKIEKCVMGKMNEFYadkgN-YYRNTVGDLLKFIRNIG 670 small-eared galago
ELW70899     592 RYRTLRNVGNESDIKKLKPKskILELLNPGPSDCSRSfsQWTKEIDEYVMKKMNKFYeknrN-FYKDTVGDLLKFIRNIG 670 Chinese tree shrew
ELK16199     592 RFRILRNVGNESDIKMRKQAsrILQILQPRTTE-QFSfdRWTTQIDSYIMKEMNNHYvksrN-FYQNTVGDLLKFIRNLG 669 black flying fox
XP_003411014 602 RYRTLRDVGNESDIKLRKTKsvILQILKPRTSEHSLSfaMWTSKIDQTVMTKMNEFYknrrNyYYRDTVGDLLRFIRNLG 681 African savanna...
XP_008251854 595 RFRTLRNVGNESDIKSRKPGsrLLQLLQPGPSERHTSfaRWTRKIHKGVMRDMNAFYkdsgS-FYKNSVGDLLKFIRNIG 673 rabbit
4YZ9_A       348 HHYRELPAE--VRETLGSlPDDFVCYFTSRFPHLLAHTYRAM-ELcSHERLFQPYY 400
ABF55365     670 EHINE-DKNkeMRLIIEE-P---SRYLQMKFPDLVIYVYKKLqNT-EYRKHFPKIH 719 dog
XP_005319780 672 EHINEEKNKw-MKKKIGD-PSCY---FQKTFPDLVIYVYRKLqNT-EYRKHFPQTH 721 thirteen-lined ground squirrel
NP_001166526 665 EHIDEEKNKw-MKEIIGE-PSHY---FQKTFPDLVIYVYTKLrDT-AYARHFPQTY 714 domestic guinea pig
XP_003264481 671 EHIDEEKHKk-MKLKIGD-PSRY---FQKTFPDLVIYVYTKLqNT-EYRKHFPQTH 720 northern white-cheeked gibbon
XP_003785845 671 EHLDE-KKNkkIKAVIGD-PSSY---FQNKFPDLVVYVYTKLqNT-EYKKHFPETQ 720 small-eared galago
ELW70899     671 EHIDE-DKNkdLKSKIGD-PSCY---FQKKFPDLVIYVYTKLqDT-EYKKHFPNTH 720 Chinese tree shrew
ELK16199     670 EHVNE-EKNkvMKSIIGD-PAQY---FQKKFPDLVIHVYVQLrDT-EYGRHFPKTH 719 black flying fox
XP_003411014 682 EHINE-EKNkdMKLKIGD-PSWY---FQKMFPDLVVYVYTKLqDT-EYNKHFPKTQ 731 African savanna elephant
XP_008251854 674 EHIHE-DRNrrMKAQIGD-PACY---FqKTFPDLLMYVYRKLrDT-EYRehfpqlt 723 rabbit
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap