5N2J


Conserved Protein Domain Family
UDP-g_GGTase

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pfam06427: UDP-g_GGTase 
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UDP-glucose:Glycoprotein Glucosyltransferase
UDP-g_GGTase is an important, central component of the QC system in the ER for checking that glycoproteins are folded correctly. This QC prevents incorrectly folded glycoproteins from leaving the ER.
Statistics
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PSSM-Id: 399437
View PSSM: pfam06427
Aligned: 164 rows
Threshold Bit Score: 94.8558
Threshold Setting Gi: 448092394
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5N2J_B       1022 EGHSREIPGAHAPRGVQLVLET---ENNPH--FADTIIMANLGYFQFKANPGVYNIRLK-EGR-SSEIFTLESV---GAK 1091 Chaetomium th...
Q6BJN0       1078 EGYAKNVKYGMNLSGLTIDL-----SKDNS--YTDTTVMSNLGYFQLSANPGIWEFKIKpESK-SEKYYSLLSA---SEN 1146 Debaryomyces ...
ABN66217     1067 EGYARNVANGNAPSGISMKL-----AKSGS--ITDTIVMSTMGYLQLSALPGIWKLFLD-SGK-SSKHYSLLSA---SSN 1134 Scheffersomyc...
XP_004197533 1058 EGFARNVVLDVPASGVSLSL-----ENRVT--TKNAVVMSNFGYFQLQAVPGAWKISIF-SAEdAKDDFVLLSA---SKK 1126 Pichia farino...
KYQ99832     1075 EGSCLDVTLRGPPAGLEIELTP---VGNSLteTQDTIVMSNLGYYQLKSNPGIWKLSLK-PGR-SSDISQI------YDS 1143 Tieghemosteli...
XP_003291934 1166 EGSCNDVSTDAAPAGLEILLNPvatQNKVT---QDTIVMNNYGYYQLKSNPGIWKLTLA-KGR-SSDIMNIVEA---NGE 1237 Dictyostelium...
Q8T191       1206 EGSANDMTTDNAPAGLELLLNPistQTNKT---QDTIVMNNFGYYQLKSNPGIWKLTIA-PGR-SSDIMDMVDH---PNQ 1277 Dictyostelium...
EFA83957     1106 QGSALDISNYQPPGGLELQLSS---LNSKV--STDTIVMGN-GYFQLQGNPGIWTLDTI--GR-GVDIFDTLNLvdrKAS 1176 Heterostelium...
XP_001583889  914 EGMCLTTQQDT-ASGTELQLTN---EMNER--ESDTIVMQN-GYYQLQGKPGIWNIELG-GSR-SASIFEL-SK------ 977  Trichomonas v...
EAY22446      949 EGSALDEQY-IPVHGLRITLDM---DKKGF---HDSLSIKTMGYFQLKTQPGIWEISLG-EGP-SRTVYNISSR------ 1013 Trichomonas v...
5N2J_B       1092 G-Wg---PIPG-DD--NTEVVLMDFQGTTLYPRLRRKPGMEEEDVLE 1131 Chaetomium thermophilum var. thermophilum DSM ...
Q6BJN0       1147 V------FISNtDPlgSVRVAILNLNGLVLKPRFTTNSGYENKFIFE 1187 Debaryomyces hansenii
ABN66217     1135 K------FEANtASleYVDIGIFNLNGQLIFPRLRKNPGYEGVEFSN 1175 Scheffersomyces stipitis CBS 6054
XP_004197533 1127 R------FNSNtKPisDAAVNVFSLDGELLRVRLAPDEGLQGSKKSA 1167 Pichia farinosa CBS 7064
KYQ99832     1144 D------KEITlDH---QSVIIDQLYVPTGNLYIRRKKGKEYESLIQ 1181 Tieghemostelium lacteum
XP_003291934 1238 -------MVPY------HTVVIDSLFQPQSSLYVQRKQGQERTPILQ 1271 Dictyostelium purpureum
Q8T191       1278 KeKetfvIVPH------RLVVIDSLYQSLSSLSVVRKAGQELRPILQ 1318 Dictyostelium discoideum
EFA83957     1177 S-LknahSVPH------LLVYIESFRGSNAFLGLKRKQGQEATPVLP 1216 Heterostelium album PN500
XP_001583889  978 -----------------SQVVIDSFVSPMKIIKVKYLPGKEGMEVNN 1007 Trichomonas vaginalis G3
EAY22446     1014 -----------------NQFSISSFVPPWMTMRVNHNDGMSRYTIYE 1043 Trichomonas vaginalis G3
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