Conserved Protein Domain Family
Neugrin

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pfam06413: Neugrin 
Neugrin
This family consists of several mouse and human neugrin proteins. Neugrin and m-neugrin are mainly expressed in neurons in the nervous system, and are thought to play an important role in the process of neuronal differentiation.
Statistics
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PSSM-Id: 399425
View PSSM: pfam06413
Aligned: 6 rows
Threshold Bit Score: 302.226
Threshold Setting Gi: 47228767
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
NP_001122120  78 MEPRGPPERRLTWNAIEEIRYLKQEFPDEWTVPRLAEGFNVSTDVIRRIIKSKLSPPERRKAKQDIKVsnvliqpnkqsT 157 tropical clawed...
Q99KS2        73 MEAPGAPPRTLTWEAMEQIRYLHKEFAESWSVPRLAEGFDVSTDVIRRVLKSKFVPTLEQKLRQDQKV-----------L 141 house mouse
Q2HJC0        73 MEASGAPPRTLTWEAMEQIRYLHREFSESWSVPRLAEGFDVSTDVIRRVLKSKFIPTLEQKLKQDQKV-----------L 141 cattle
Q5R7E7        73 MEASGAPPRTLTWEAMEQIRYLHEEFPESWSVPRLAEGFDVSTDVIRRVLKSKFLPTLEQKLKQDQKV-----------L 141 Sumatran orangutan
NP_001038718  87 MNTPGAPQRKLSWDAIEQIRYLKQESPEEWTLQRLAEGFSVSPDVISRVLRSTFTPPAARKLKQDAKV------------ 154 zebrafish
CAG07499      37 MTPPGAPKRRLSWDAIEQIRYLKEEQPEEWTIQHLAEGFSVTPDVVLRVLRSRFVPSVERRAKQDAKA------------ 104 spotted green p...
NP_001122120 158 KHLSQPTQTLLLGALNPAQALIPSGQndkl---kintQTSDlVLSPGSLPAS-ANRN-SLLLRSENEMMQRNKANLQVCT 232 tropical clawed...
Q99KS2       142 KKAGFTREIGQLPVSEDTLKALSAGR-----------SVSG-LLMAGDEVSS-KSQNhSTALKVAKSHPHSTDAQKKREG 208 house mouse
Q2HJC0       142 KKIGLARSIPELPGPGDSSKPLSAGQ-----------SVSGsLLIPGDEASS-RGHGhSTALKAIELNTQSTNITTRQTE 209 cattle
Q5R7E7       142 KKAGLAPLLQQLRGSGNTSKLLPAGH-----------SVSGsLLMPGHEASS-KDPNhSTALKVIESDTHRTNTPRRWKG 209 Sumatran orangutan
NP_001038718 155 -------------SPSSGPQYLKDGKaeqs---rlqkSLTPsVLLPS------ANTShS-ALKTLDTKQTGLTPSAGHIT 211 zebrafish
CAG07499     105 -------------MAGPGPKVLPSGSkrvqdrlklpgNLPPaLLPPGKEAGAvAPAEqGLALRGDGL------ATLAKRQ 165 spotted green p...
NP_001122120 233 KKAQVQTPKSamYDVGPTSEEGSQAEqq-hCVDDKQMELDEWDGQLLSDTDLEELSRSGIEN---KMKVIQRGREFFDSN 308 tropical clawed...
Q99KS2       209 RDKRIQVLEE--SLVPATTALGHQRElqksATSDSEATGRAGSDTLPSAVLLEELKPGEPGDqsfSSKVVQRGHDFFDSN 286 house mouse
Q2HJC0       210 RNKGVQGLEEgkDFVPVAA--GHP-------TSTCRGARGIDSDGLPSDKRLEELKAGEAGDqifSKRVVQRGREFFDSN 280 cattle
Q5R7E7       210 RNKEIQDLEE--SFVPVAAPLGHPRElq-kYSSDSESPRRTGNGALPSDQKLEELKAEEPGNf--SSKVVQRGREFFDSN 284 Sumatran orangutan
NP_001038718 212 LSKQTAVLNVapEYQDRLESKGEM------DVNDDVEFEEEWDGVILTDEELEKITQTLHEK---PSPVEQRGRDFFDSE 282 zebrafish
CAG07499     166 TPALVQQLGDlsSNVSGTEPTGLDRS----THTDPAEEEEFWDGRVFTEDDLEEFM--EIGK---PPLAVQVGKEFFDAE 236 spotted green p...
NP_001122120 309 GDFLYRI 315 tropical clawed frog
Q99KS2       287 GNFLYRI 293 house mouse
Q2HJC0       281 GNFLYRI 287 cattle
Q5R7E7       285 GNFLYRI 291 Sumatran orangutan
NP_001038718 283 GNFLYRV 289 zebrafish
CAG07499     237 GNFLYRL 243 spotted green pufferfish
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