Conserved Protein Domain Family
Pex24p

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pfam06398: Pex24p 
Integral peroxisomal membrane peroxin
Peroxisomes play diverse roles in the cell, compartmentalising many activities related to lipid metabolism and functioning in the decomposition of toxic hydrogen peroxide. Sequence similarity was identified between two hypothetical proteins and the peroxin integral membrane protein Pex24p.
Statistics
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PSSM-Id: 399414
Aligned: 51 rows
Threshold Bit Score: 152.192
Threshold Setting Gi: 74644185
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
O59807         1 M-IRAHLFSEPD---NSKLWAKSTGSdafDLILKVLLWTAPWYYCLTTLFFTWLIILYPRPTLaCSVAAWLFWFTSLDTL 76  Schizosaccharom...
EAZ62814     131 PnLSIRILLSNFkklAGKMGMFFELQ---YGIIHIITWRKPTKTLTALVLYTTICLWPHLVVT-YPLIFLLFGIIVPGYL 206 Scheffersomyces...
Q5ANG0       154 PgLSFGILTSNVkqmASKMTNFFALQ---YEVLYIIAWKKPTKTISALVLYTAVCLWPHLVLA-YPLLFVLFGVLIPGFV 229 Candida albicans
XP_001526337 165 PgLSFPILISNLkqlGSKMTNLFALQ---YEIINIVAWRKPNKTLSVLVLYTAACMWPHLILV-YPLLFVLFGMLLPGYT 240 Lodderomyces el...
XP_001486482 131 PgLSILVIAGNFkalSGRMTGFFTVQ---YGLIHIITWRHPSKTLTFLVFYTATCLWPHLVLA-YPLLFLLFGIMIPGYI 206 Meyerozyma guil...
EDO19199     152 QpISASTLGRNMgklGSKMTAMFDMQ---ETVIRLITWRNPSGTVTLLISMTMLFYNPIILLL-LPLVTLMYMVMIPGYI 227 Vanderwaltozyma...
P38848       201 PvFSATTLGSNFkklSKKMGSIFELQ---DSIVRLLTWRNPTGTVTSLILFTLICFNPMYLVI-LPIFRFVYGIVVPGYV 276 Saccharomyces c...
Q6FR12       140 PpFSASVLASNMkklSGKMDSIFEFQ---DNMIRVLTWKTPTVTLTALTIFTLICFDLMNVIL-FPMAYIVLVQMTQGYI 215 [Candida] glabrata
Q6CN25       177 QtVSVTIMNKNVralTSRLGAIFELQ---DILIRLLTWRNPSGTLLALIAFTQICFNPMLLVI-LPILYLMFGLMIPGYL 252 Kluyveromyces l...
Q75AQ6       185 HpISLIIMSRNLkimTTKLGLIFEFQ---DSLVRLATWRNPSGTALSLILFSFACFNPMLVII-LPMLYVLFGLMIPGYL 260 Eremothecium go...
O59807        77 EP-DDrkntlkaseavstsaktseetakpsetredgewntlkntleadaqnlmsgfqmlqrrwsqpktttlktevkeQQA 155 Schizosaccharom...
EAZ62814     207 HRhPMrtpelikvkkrgqslfsflnegagehsiiddllsd--svlgdeglrptfsgseessdvlqispsevisetsvSTD 284 Scheffersomyces...
Q5ANG0       230 HRhPQrnpelikvkkrgqsllsflf---------------------------------etpetsivedlineeylqasDE 276 Candida albicans
XP_001526337 241 HRhPPrrpdlikvksrgqslfkflna------------------------------teetsivedlvdteylkedadIAD 290 Lodderomyces el...
XP_001486482 207 HRhPMqtpelikvrkrgqs--------------------------------------------lleflsssdetsivDDI 242 Meyerozyma guil...
EDO19199     228 HRhPLhraiypsrtsygrsllediass-----------------------------gpsnawypnntlveslnelqsGDS 278 Vanderwaltozyma...
P38848       277 RKhPLqrsiyplkrnhgssllydvcye-----------------------------gkneysygqqffsksfmdtleSRN 327 Saccharomyces c...
Q6FR12       216 RRhPIrrtiyikrraigrslihdlf---------------------------------hggkktnnvllpsnendcnGEQ 262 [Candida] glabrata
Q6CN25       253 HRhPLhrgiylskrsygksliksittg-----------------------------gntsklqlrdsihefnyedidIND 303 Kluyveromyces l...
Q75AQ6       261 HRhPLrrnfyltkhsygksllatvatg-----------------------------gkpaswqshddvqefdynnlhTDT 311 Eremothecium go...
O59807       156 SQSPSVEgenepagvksneatkpsvt----------------eekeknaeqnkrrerlsisHIVTELAkkdevssesgsn 219 Schizosaccharom...
EAZ62814     285 DSKKPIAks--------------------------------------------------qlALLINMR------------ 302 Scheffersomyces...
Q5ANG0       277 VASSTYSiseetsevtvsssmptd--------------------sespkkddvakhrksqiALLINLR------------ 324 Candida albicans
XP_001526337 291 VNSTSYTmseaesdntkastavsvssqgg-----------tessekldkkkevskrrkrnlDLLVNLR------------ 347 Lodderomyces el...
XP_001486482 243 VEDRTLRsaendldpvssrssdtssaftqapisasalstsssdvnekvkkdekaryvksqmKLLMNMR------------ 310 Meyerozyma guil...
EDO19199     279 GATSNFSdtnsv---------------------------------------------shsmAVVMNLR------------ 301 Vanderwaltozyma...
P38848       328 QEIDEISeldkrten--------------------------------------tgelkqgmKVLINLR------------ 357 Saccharomyces c...
Q6FR12       263 ENEADLGtsddcngtsdenvvispa-------------------aakidknistynlnhgtKVVLTLR------------ 311 [Candida] glabrata
Q6CN25       304 LRKANTvrq--------------------------------------------------smEFVVNLR------------ 321 Kluyveromyces l...
Q75AQ6       312 EEWERALhik------------------------------------------------qtmEFIVNLR------------ 331 Eremothecium go...
O59807       220 eivNAKLKNEQLDSNFTLLDayleplvhlheysRRSNTLFFFYLPIVMSILIFCL----PTQALFIVLS-SVFLAWHSPP 294 Schizosaccharom...
EAZ62814     303 ---DLQNLTTDLLNGMDLAEkswfe---tfgfkDEHLSTFIFYGVAAATSVVLFLgqfiPWRLIFIQSGwAGILLCHPKS 376 Scheffersomyces...
Q5ANG0       325 ---DFQNLTTDILKGINNAEkfyye---tggfkDERLSTFIFYGVLLSTFGILFVgkyvPWRLIFIQGGwTGAILCHPNC 398 Candida albicans
XP_001526337 348 ---DMQNSMTDLLKLIEEGEtfyye---tagfkDERLSTFIFYGVLVATFGAIFFgqfiPWRLIFIQSGwIGLTLCHPKV 421 Lodderomyces el...
XP_001486482 311 ---DLQNLTTDLLQGFDAAEvfwyq---tagfkDERLSTFMFYGVILATSIILFLgtfiPWRLIFIQSGwAIVLVCHPRS 384 Meyerozyma guil...
EDO19199     302 ---DVQNITTSLVQVSQATDkfiyg---aagfkDERRSTILFFTCFLATGCLWALapyiNWSFFFSFNTwLILICIHPNI 375 Vanderwaltozyma...
P38848       358 ---DMQNMTSGTLHVIEAINsflrk---sssfqNEECSTKRFFTGFLLIVFLKILspfvNWSYVCSIFAwCLLIYMHPRA 431 Saccharomyces c...
Q6FR12       312 ---DMQNMTTGTVHLMDAIDkfkyg---taafvDEYKSTSVFFTLLGSVILLVLLsrfiTWSLTISLSAwIGLLSIHPKV 385 [Candida] glabrata
Q6CN25       322 ---DLQNLMSTLVSVIDKMEkfmyg---tagfkNEQYSTVVFLSCFVVLFLLWIItpfiNWGLMASLLAwSIMTIIHPRV 395 Kluyveromyces l...
Q75AQ6       332 ---DLQNLMTASVKGIECAEkfvyg---dagfkNEHHSTVLFLSGLLVVMGLWIIapyiNWSLTSAAGAwAALILIHPRV 405 Eremothecium go...
O59807       295 LQAVLFciRrisffnllyEKFVIGKTKEpakpvpqpssnepp---apsaenkqpsvsspEKKESPATHllkvigsspyvv 371 Schizosaccharom...
EAZ62814     377 KTFLVE--------------LSNAKKARaak--------------------------apQPEEIIESEvkkfetndi--- 413 Scheffersomyces...
Q5ANG0       399 KKFLVD--------------ASKARKARaaiekakkeeksv-----peiiieeaddtvtQFDrndiivd----------- 448 Candida albicans
XP_001526337 422 KKFLVD--------------FGAAKKRRskviqrnaeaaqkadptaettsnkglkqlltQLDrndiivd----------- 476 Lodderomyces el...
XP_001486482 385 KKYLKA--------------LSENKKRKaaa-------------------------kpkKVKEEKDEDgpavydrndi-- 423 Meyerozyma guil...
EDO19199     376 REHLLK--------------LMESDKVEeg-----------------------------------rKAlekkerydv--- 403 Vanderwaltozyma...
P38848       432 HPKIIS--------------FFKTGTMGke-----------------------------------yKNlkkrehqaln-- 460 Saccharomyces c...
Q6FR12       386 HPYVKS--A---------KNIMKKPKMKpen--------------------------spQDVAVVMEDnisgedynrn-- 426 [Candida] glabrata
Q6CN25       396 RPTVFG--------------LLKKEQLDkg-----------------------------------kEAlrrterydi--- 423 Kluyveromyces l...
Q75AQ6       406 LPMVTA--------------YINDDQLEkg-----------------------------------kVVienverydi--- 433 Eremothecium go...
O59807       372 hsnhtnntltdkessdptekCLYLIEHQRYW-VGVGWLNRTLPTDPPNFTNAgstDPVAePT-----AQLLPPDGLAWID 445 Schizosaccharom...
EAZ62814     414 -----------ivddaperrIVEIFELQKKSiLHEKWTFYSYSGNIFDTKKKtrlAGKR-PGgvdhlSKVVPPKDWLFDF 481 Scheffersomyces...
Q5ANG0       449 --------------dspearTVEIYELQIKSiLKHSWTFYRYSTTIYDKNNKariAGKR-PPgvdhlSKVYPPNDWKFDF 513 Candida albicans
XP_001526337 477 --------------dspevrLVEVYELEIKSiLQNDWKFYRYSNTIYDRLNKnrlSGKR-PPgvdhlSKVFPPTDWKFDA 541 Lodderomyces el...
XP_001486482 424 -----------iiddapevrICEIFELQVKSlTKNEWSFYCFTSSAFDVKNStrsAGKK-PQgvnhlYKILPPPDWKFDM 491 Meyerozyma guil...
EDO19199     404 -----------ildekpevkHVEIFEILEQGiTPHHWKFYKFSNQVFDPHDQyrkLQQP-PPgvdnlKDIEPPRTWYFDE 471 Vanderwaltozyma...
P38848       461 ----------mifdeqpetkFIEIFEIYKKAlLPNDWKFFRYSNRIFDPQDPyrrAQQF-PPgvdslADVIPPTGWSFDP 529 Saccharomyces c...
Q6FR12       427 ----------iildeppdvkYVEVYEIYKRGlLPTDWEFFKFSSTIFDPTDTyrkALQL-PPgvdkiEEIKPPAGWAFDE 495 [Candida] glabrata
Q6CN25       424 -----------lldepvetrWVEVFEIQMQGiTEQEWSPYMYSTQVFDKSDPyrkSQKP-PPgahsmDDLKPPPTWTFDS 491 Kluyveromyces l...
Q75AQ6       434 -----------lldekpeerYLELFEIYKQRlTSDEWDFYLLSSYAFDPTDKyrkSQRP-PPgvtniDEVVPPSMWSFDR 501 Eremothecium go...
O59807       446 ---DKWSISP--------------------------WTFTdtfWAQPAK-TQFRTAFTRSREWRR 480 Schizosaccharomyces pombe 972h-
EAZ62814     482 gfaNKWTIDYepqeflrqrsles-knlviregeksgWIYD---KDVESQ-SSDITYEFRRRRLYR 541 Scheffersomyces stipitis CBS 6054
Q5ANG0       514 glvNKWNLDTkpkeflrerslnp-nlfivkndesqgWIYD----NMEGIvYSDIVYEFRRRRLYR 573 Candida albicans
XP_001526337 542 efvNKWVLDTnpmdfikqrtlda-slfvikddenegWIYD----NMKNVvNLEIVYEFRRRRLYR 601 Lodderomyces elongisporus NRRL...
XP_001486482 492 syaDNWHVDKepqnflkerswdklnmfvikededegWMYD----NEDMIeNKDEQFDFRRRRLTR 552 Meyerozyma guilliermondii ATCC...
EDO19199     472 n--APWEVDPnakkwseer--------glnltisgqYLVD---------------DQFKRRRLTR 511 Vanderwaltozyma polyspora DSM ...
P38848       530 n--FEWKIDNdvdrwvver--------glnlpitgeFLFD---------------PMFKRRRLIH 569 Saccharomyces cerevisiae S288C
Q6FR12       496 n--SSWIIDKnpeiwaier--------glqlpveegFLVD---------------PMFKRRRLVR 535 [Candida] glabrata
Q6CN25       492 n--SEWTTDTnveqwaterg-------lemtriegdYLVD---------------DQFKRKRLIR 532 Kluyveromyces lactis
Q75AQ6       502 n--SKWEVDYdvkgwaqer--------glsleingeFLVD---------------DSFKRRRLTR 541 Eremothecium gossypii
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