Conserved Protein Domain Family
Herpes_IR6
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pfam06307: Herpes_IR6 
Herpesvirus IR6 protein
This family consists of several Herpesvirus IR6 proteins. The equine herpesvirus 1 (EHV-1) IR6 protein forms typical rod-like structures in infected cells, influences virus growth at elevated temperatures, and determines the virulence of EHV-1 Rac strains.
Links
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Statistics
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PSSM-Id: 253668
Aligned: 4 rows
Threshold Bit Score: 270.26
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
NP_045284  52 SQEPRKYLFNPYKYMLGRPYFRRCREEMNEGYFAKVPEGYFPVGPSEMPGRVPVES-----KVDGEVLSFKALPPPKFEK 126
Q6LAQ8     54 PRGERKHLFNPFGCMLGRSYFRRCREEMNEGYFAKVPTGYFPVAPSEVPCRVPVEG-----VVAGEVLSYSALPLPKIEK 128 Equine herpesvirus...
Q6X204     25 ASAAADAGPGRDGGPVGWRLFRACRNEHEDGLYAMLPPDYFPVMPSTKPLLVKVPApglspDRAGGAVHFECVPAPRRPV 104 Bovine alphaherpes...
O41520      1 MSASFALFDNNSDQANMPSYFRRCRGELNEGFYAQVPPGYFPVRPKTTPALARVKN-------QGEPHAFTIVPTPPTDV 73  Canid alphaherpesv...

NP_045284 127 RFYKQLDDGTFVRLPFLYPEEYYEGENQPSETLYYIRADTKDAYS----VDPSDLLEEAFAEVPKWLE-EEMSNWTGPKK 201
Q6LAQ8    129 RFYKQLNDGTFVRLPFLYPEVYYEGEEEPADERYYIRADAADASS----ADPSTLPEEAFAKVPPAIA-EGITNWQGPKR 203 Equine herpesvirus...
Q6X204    105 QFFRQLYDGTFVRLPHNFPDECYEDE-APLADRFYLNADVDLQSL------PAGNMSQYFTRLPDAFQrELRARVPAPAR 177 Bovine alphaherpes...
O41520     74 RFFKKLRDGTFVKLPFSYPDERYEDDIEPMYCRLYVLKDFETPSSpynqVNASQLME-----VPSSLV-ESKCYWDGPKF 147 Canid alphaherpesv...

NP_045284 202 LPIPSRRYVLKHGWE--FQSNVTEDAFQEINTTFLRLDLQGEPkqhtrnaqqssigdqvlDAHPRDAQQPKNGNSVDKN 278
Q6LAQ8    204 IPIPSERYVMKLGFE--YQLHVTEDAFQEVNTSFMRLDLQSSP-----------------DPHPRGARQPRSRAHVSAE 263 Equine herpesvirus ...
Q6X204    178 TPLPHRRYVLRLGLErvAGERFTEDCFEPIDTRLLRLERAPGEpp-------------rrGPPQPPAGPGPRRARVRAG 243 Bovine alphaherpesv...
O41520    148 INVPPIRYILKSDYS--LN-NVSEDAFVLVDTRKLKLE----------------------------------------N 183 Canid alphaherpesvi...
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