3FB9


Conserved Protein Domain Family
VEG
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pfam06257: VEG (This model is not part of the current CDD release)
Biofilm formation stimulator VEG
VEG is a family that is highly conserved among Gram-positive bacteria. It stimulates biofilm formation through inducing transcription of the tapA-sipW-tasA operon. The products of this operon are resposible for production of the amyloid fibre (TasA) component of the biofilm. Veg or a Veg-induced protein acts as an antirepressor of SinR - part of the major overall biofilm transcriptional control system - to regulate and stimulate biofilm formation. Veg is transcribed at high levels during both exponential growth and sporulation.
Links
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Statistics
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PSSM-Id: 517187
Aligned: 87 rows
Threshold Bit Score: 49.7737
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3FB9_A         22 AHEGQVVEMTLENGRKRQKNRLGKLIEVYPSLFIVEFgdveG----DK--QVNVYVESFTYSDILTEKNLIH 87  Streptococcus pneumoni...
WP_014081707   12 GHLGSDIKVTEQAGRKRTNEYEGVLSEVFPAVFIVDL----E----SN---EQPAQASFTYSKILTEDIEVT 72  Fructilactobacillus sa...
12_pfamImport  12 EHVGQTIEITSQFGRKRENRHKVNLIETYATHFVIE----------NIpaRGPKTTESYQYADILTQTILIH 73 
WP_002938218   20 DHEGQIVELTLENGRKREKNKQGRIVEVYQSLFIVEF----E----DP---NNTFVESYTYSDILTEKILIH 80  Streptococcus
Q8DMZ3         20 AHEGQVVEMTLENGRKRQKNRLGKLIEVYPSLFIVEF----GdvegDK--QVNVYVESFTYSDILTEKNLIH 85  Streptococcus pneumoni...
WP_013252521   20 TLQGKRIRVRANMGRSRIVERTGTLVGAHPSLFVVEV----E----ER--RGRTARQSYQYVDVLTSTVELy 81  Olsenella uli
WP_012808264   20 ELQGQKIKVKANMGRSRIIERTGVLVNAHPSLFIVEV----G----ER--RGRTARQSYQYVDVLTGTVELf 81  Lancefieldella parvula
WP_012797910   19 SRTNTRLKVRANMGRSKIIECEGTLMQTHPALFILEV----D----RK--RGRTARQSYQYVDVLTGMVELy 80  Slackia heliotriniredu...
7_pfamImport   12 DFVGQRLKVRANMGRSKIVESEGVLMQVHPQLFILEV----D----RK--RGRTSRQSYQYVDVLTGMVELS 73 
5_pfamImport   12 SNIGKDVIVEADKGRNKIVTNKGTISQVFPSLFTIKV----T----NE--YDSERTISYTYSDILTSTVKLE 73
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