Conserved Protein Domain Family

pfam06247: Plasmod_Pvs28 
Pvs28 EGF domain
This family consists of several ookinete surface proteins (Pvs28) from several species of Plasmodium. Pvs25 and Pvs28 are expressed on the surface of ookinetes. These proteins are potential candidates for vaccine and induce antibodies that block the infectivity of Plasmodium vivax in immunized animals. The structure of this protein shows it is composed of four EGF domains.
PSSM-Id: 399333
Aligned: 36 rows
Threshold Bit Score: 24.6315
Threshold Setting Gi: 0
Created: 21-May-2020
Updated: 7-Aug-2020
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
Format: Row Display: Color Bits: Type Selection:
1Z27_A         7 VTVDTICKNGqlvqmSNHFKCMCN------------------------------EGLVh--LSENTCE 42 
Q8IJ96       160 CAENEVCTLE-----GNYYTCKEDpssngg------------------gntvdqADTSysvINGVTLT 204 Plasmodium falciparum 3D7
Q7KJ23       159 CKATEECKLV-----GTYYECISKnpapgtgsgtgs-------gtgsgtgsgtgTPANssiMNGMSIF 214 Plasmodium yoelii yoelii
Q7KQL2       162 LKENETCKAV-----DGIYKCDCK------------------------------DGFIi-dNESSICT 193 Plasmodium falciparum 3D7
XP_002261828 164 NTENEVCKAV-----QGVYKCQCM------------------------------EGFKf-dKEKKECI 195 Plasmodium knowlesi strain H
1Z27_A       147 NTDNEVCKNV-----EGVYKCQCM------------------------------EGFTf-dKEKNVCL 178
XP_002261827 160 CKGNEQCKLT-----DNYYQCPSDgsggqgsgge----------gnggegsggsTGAAyslMNGSAVI 212 Plasmodium knowlesi strain H
XP_675906    159 CKAAEECKLT-----GKHYECVSKpqapg---------------------tgseTPSNssfMNGMSII 200 Plasmodium berghei ANKA
XP_675324     24 iSPNTQCKNGflaqmSNHLECRCN------------------------------EKFTh--VSNNTCK 59  Plasmodium berghei ANKA
AXG32430     160 CKANEECKET-----QNYYKCVAKgsggegsggegsggegsggegsggegsggdTGAAyslMNGSAVI 222 malaria parasite P. vivax
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