Conserved Protein Domain Family
Orthopox_A5L

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pfam06193: Orthopox_A5L 
Orthopoxvirus A5L protein-like
This family includes several Orthopoxvirus A5L proteins. The vaccinia virus WR A5L open reading frame (corresponding to open reading frame A4L in vaccinia virus Copenhagen) encodes an immunodominant late protein found in the core of the vaccinia virion. The A5 protein appears to be required for the immature virion to form the brick-shaped intracellular mature virion.
Statistics
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PSSM-Id: 283778
Aligned: 2 rows
Threshold Bit Score: 204.059
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P0DOP1   1 MDFFNKFSQGLaeSSTPKSSIyySEEKDLDI--KKDEAIEIGLKSQESYYQRQLREQLARDNMMAasrqpiqplqptihi 78  Variola virus human/I...
Q9Q8K7   1 MDFMVEYEKWI--DATARNTA--TEEDDPNPlgRRPGTGRTRFESSERQYQQQLIEQLRKQQMLR--------------- 61  Myxoma virus
P0DOP1  79 tpLQVPtpaptpkprqQQTNTssdmsnlfdwlsaddntqpssllpaltpinavqdiiskfnkdqkttttpstqpsqtlPT 158 Variola virus human/I...
Q9Q8K7  62 --IEIP----------QELGT---------------------------------------------------------PS 72  Myxoma virus
P0DOP1 159 TTCTQQSDGSISCTTPTVtppqppivatvctptPTGGTVCTTAQqnpnpgatSQQNLDnmalkdlmsSVEKDMRQLQAET 238 Variola virus human/I...
Q9Q8K7  73 TSCVRNVDASSATSTDIV---------------PVDRRICTVPD--------IQKELD---------SVKTETCSLQRQS 120 Myxoma virus
P0DOP1 239 NDLVTNVYDAREYTRRAIDQILQLVKgfERFQK 271 Variola virus human/India/Ind3/1967
Q9Q8K7 121 EDLISDISMAKDSTFGAINALMDDLR--KRFQS 151 Myxoma virus
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