5N7W


Conserved Protein Domain Family
IL17

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pfam06083: IL17 
Interleukin-17
IL-17 is a potent proinflammatory cytokine produced by activated memory T cells. The IL-17 family is thought to represent a distinct signaling system that appears to have been highly conserved across vertebrate evolution.
Statistics
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PSSM-Id: 399226
Aligned: 94 rows
Threshold Bit Score: 53.4187
Threshold Setting Gi: 321472801
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5N7W_X         69 RSTSPWNLHRNEDPERYPSVIWEAKCRHLG---CIN-ADGNVD--YHMNSVPIQQEILVLRRep---phCPNSFRLE--K 137
XP_002604638   94 RSMCKWRYEDNVDPNRFPSTLKVAV-KEYTgsrCRDpATGAPR--ADLACLPIDYELNVLRKn------SEGEWQES--Y 162 Florida lancelet
XP_002604659  169 RSVCPWRYDDDFKANRFPHTLRVAV-KTHTgsrCIDpATGAPR--RDLRCLPVEYKLNVLRKd------SEEVWQISadP 239 Florida lancelet
23_pfamImport   1 RSLCPWRYVLHSDNNRYPRDIIFVQCECQE---CVDpELGVFSs-NRDLCRPVIHNHHVLRRtge-cinGVQRYEEQ--F 73 
AIR74621       53 QSICPWSTIMVEDNDRVPRQLPSTTCTKSS---VVFqLNGTP---VEYACELVEVTVSVLKYh------PSGYWERS--D 118 Pacific oyster
XP_002594253   94 RAYCPWQVIVDSNPNRFPTDIAYARCQSTF-----PsQDGEYN--WTMACDSVTYTKPVLVReecsgadNTYRYKCV--H 164 Florida lancelet
XP_002606350  346 RSVCPWSYYIDHDPNRVPHDIAQAKCRCTA---CLDpVTKKQN--YNYACVPVTIQKLVYRRkkk--ksGGYRYREE--W 416 Florida lancelet
XP_030848450   68 RALCPFVMETDTDVERYPQDILSARCACRD---CINpYNNGFItnPGVDCMPVVREMETLRRgqc--vgGVYRYEKQ--R 140 purple sea urchin
XP_011674283  103 dgMCPWTYVECFDSDRIPMSISMAQCQCSA---CLDpYSHQAD--PNLRCQPIFHNMKVLRKtqc--vdGLYRYEEE--T 173 purple sea urchin
XP_030839411   97 ngLCPWTYVECFDADRIPMGLQVAQCQCSG---CLDpYTHTPN--PNLQCTPVKRNIKVLKKtqc--agGMYKYEEQ--N 167 purple sea urchin
5N7W_X        138 ILVSVGCTCV 147
XP_002604638  163 EFVTIGFTCa 172 Florida lancelet
XP_002604659  240 EFVTVGYTCa 249 Florida lancelet
23_pfamImport  74 EPVPMACVC- 82 
AIR74621      119 ELVPVACTAV 128 Pacific oyster
XP_002594253  165 LTVPNACVAV 174 Florida lancelet
XP_002606350  417 QGVTVGCTCV 426 Florida lancelet
XP_030848450  141 TKVPVACVCa 150 purple sea urchin
XP_011674283  174 VKVPVACGCM 183 purple sea urchin
XP_030839411  168 IAVPVACACM 177 purple sea urchin
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