Conserved Protein Domain Family
DUF896
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pfam05979: DUF896 
Bacterial protein of unknown function (DUF896)
In B. subtilis, one small SOS response operon under the control of LexA, the yneA operon, is comprised of three genes: yneA, yneB, and ynzC. This family consists of several short, hypothetical bacterial proteins of unknown function. These proteins are mainly found in gram-positive firmicutes. Structures show that the N-terminus is composed of two alpha helices forming a helix-loop-helix motif. The structure of ynzC from B. subtilis forms a trimeric complex. Structural modelling suggests this domain may bind nucleic acids. This family is also known as UPF0291.
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Statistics
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PSSM-Id: 428703
Aligned: 80 rows
Threshold Bit Score: 49.0386
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
CDE52893                6 ETIARINELYKKSKETGLTNEEAMEQAKLRKEYIEAVHNNLRGILNNVQI--QNPDGTieDLKPK 68 
KuoIPMB:SDIMI_v3c04150  3 KLLKRINELAHIAKQRELTHEELEERAKLREKYIKLFRAGLEQQLENTKF--IDENGN--EIKrk 63 
AGR41303                3 KILERINVLAKIAKERELSSEELKERDELRKEYIKIFRSGLEQQLKNVVV--LDEFGN--DVTPk 63 
EDS17751                7 ELIVRINELAKKKKDGTISEAELEEQKELRQKYLKAFRSGFKQQLMGVKV--VDEEGN--DITPQ 67 
WP_022001281            7 KLIDRINVLAKKKKEGTITPEELKEQDKLRKEYIKLFREGFKSQLKAIKV--VDEKGN--DITPL 67  Faecalibacillus
WP_022424391            6 KLIDEINALAHKKKTVGLTPEEQVRQQKLRQKYLKEFRRGFEQQLQSIKV--VDANGN--DVTPA 66  unclassified Cateniba...
Q6F1B6                 11 EVIQEINRLAKIKKDRELTSEESAYREELKVLYLNYFRNGFEQQLKSTKV--IDAQGN--DVTPS 71  Mesoplasma florum
KuoIPMB:SCULI_v1c05440  3 KLLKRINELAAIQKTRSLSEEEKTEQIHLREKYLENFRAGFKDQLKSLKV--VDQKGN--DITPQ 63 
WP_012861932            5 DIIEKVNHYSQLSRTRELTEEEKEERIKYRNLYMTNFRANFKNHLDSIKVkyVDENGN--EIkgn 67  Sebaldella termitidis
WP_038673644            3 NLIARINELSKIAKTRDLTPDEKIERDNLRQEYLKNFREGFKNQLDNLKV--VNEKGE--DITPK 63  Spiroplasma sabaudiense
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