7S5H


Conserved Protein Domain Family
Inhibitor_I9

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pfam05922: Inhibitor_I9 (488034 is an unknown moldel)
Peptidase inhibitor I9
This family includes the proteinase B inhibitor from Saccharomyces cerevisiae and the activation peptides from peptidases of the subtilisin family. The subtilisin propeptides are known to function as molecular chaperones, assisting in the folding of the mature peptidase, but have also been shown to act as 'temporary inhibitors'.
Statistics
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PSSM-Id: 488034
Aligned: 70 rows
Threshold Bit Score: 43.0526
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
7S5H_A        47 TYVVVLKEETHLSQsERTARRLQA-------------Q--AARrg-------yLTKILHVFHG---LLPGFLVKMSGDLL 101 human
C5G168        37 QYIVTLKEGLASAQ-IREHKKWVSsv---------hqA--NLDsfaagasgveTVGIMKNFHIh--NLNMYSGGFDDKTA 102 Microsporum can...
P28296        36 KYIVTFKPGTDTAT-IESHTLWATdl---------hkR--NLErrdtt-sgepPVGIEKSYKIk--DFAAYAGSFDDATI 100 Aspergillus fum...
Q00208        35 KYIVTFKSGLNVDQ-IDAHTSWASnvhkrnlerrglaErd------------qYSGIEKNYKIn--KFAAYSGSFDDATI 99  Aspergillus nid...
P12547        36 KYIVTFKPGIDEAK-IQEHTTWATnihqrslerrgatGgd------------lPVGIERNYKIn--KFAAYAGSFDDATI 100 Aspergillus ory...
KLU87001      33 SYIITLKQGASAAS-FQNHLSWVGdv---------hrR--SVSkr-------dTTGVDKVFDLd--GFTAYSGSFDAATL 91 
XP_002568432  35 SYIVVMNDGVSTAQ-FETHRNWAAnv---------haRtrSLKg--------gESGPGKHFDIn--GMKGYSASFDDRTV 94 
C5FMY5        35 SYIVVMKDGVTAED-FDSHISSVAtt---------hsI--NKAkrg-----seTVGHKDSFNIn--GWRAYNGHFDEATI 95  Microsporum can...
C5FPS1        34 SYIVVMKDGTTEED-FTHHQSWVQsi---------htHn-VTRrgl-----ldNAGVRHKYGFg--SMMGYAGLFDEDTI 95  Microsporum can...
G1X8P8        39 KYIVVLKKGLSDSA-VSKHTNRISsf---------hsN--VARdlt----garAHGVGRKFRFsstGFNGYVGGFDKATL 102 Orbilia oligosp...
7S5H_A       102 ELALKLPHVDYIEEDSSVFAQ 122 human
C5G168       103 EDLRRSPDVKSVHPDQHVYLA 123 Microsporum canis CBS 113480
P28296       101 EEIRKSADVAHVEEDQIWYLD 121 Aspergillus fumigatus Af293
Q00208       100 EEIRNSADVAHVEEDQIWYID 120 Aspergillus nidulans FGSC A4
P12547       101 EEIRKNEDVAYVEEDQIYYLD 121 Aspergillus oryzae RIB40
KLU87001      92 QEIKKSDEVAFVEPDQVWDLy 112
XP_002568432  95 KDIASDPTVKYVEPDMVVNat 115
C5FMY5        96 ESILNDDKVDYVEHDRVVKLA 116 Microsporum canis CBS 113480
C5FPS1        96 KDISDDPKVMFVEPDTTITIH 116 Microsporum canis CBS 113480
G1X8P8       103 QEILNSPEVDYVEQDTVVTTy 123 Orbilia oligospora ATCC 24927
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