Conserved Protein Domain Family
Ebp2

?
pfam05890: Ebp2 
Eukaryotic rRNA processing protein EBP2
This family consists of several Eukaryotic rRNA processing protein EBP2 sequences. Ebp2p is required for the maturation of 25S rRNA and 60S subunit assembly. Ebp2p may be one of the target proteins of Rrs1p for executing the signal to regulate ribosome biogenesis. This family also plays a role in chromosome segregation.
Statistics
?
PSSM-Id: 399112
Aligned: 124 rows
Threshold Bit Score: 124.26
Threshold Setting Gi: 156082892
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
ESO05038      16 DSDKELQvAFEKGLLKDTVIVST----TnpKPKYINNKVGLEEALRNLKR----DLPWQETLDICVE-PAPLpyclkddd 86  Helobdella robusta
KJE91077      67 EEELAQAfKAGLLRADAAVPQRP----K------INNEERLRERLGDIAQqvdaSFPWAERLDLVSTvPIVL-------- 128 Capsaspora owcz...
8_pfamImport   1 DSDRELQvAFASGLLKPGLFRPI----TapPPA-INNEVGLLEKLEEISQs---DLEWVERLDVTIKrnkse-------- 64 
XP_002415028   9 dPDEELQeSLARGDLKPGLYSVV----PhvRQEHINNTAALKQKLAEMEL----DLDWIETLDMVNT-LAPLtpevkqqy 79  black-legged tick
XP_001954735  18 NSEAELQaAFERGDLKPGLNVEF----NgqRDT-VNDVTKLLSKAKDIHL----DLPWIERLDMINT-LAPLapelavql 87  Drosophila anan...
XP_001863228  19 DEDDELReALAKGLLKPGLNVIA----KdrQEP-VNNTAKLKAALESMIL----KAPWVERMDLVND-LAPLtpelaiqi 88  southern house ...
Q16X80        19 DEDDELReALAKGLLKPGLNVIA----KdrSEP-ANDPLKLKSALESLIL----KAPWVERLDLVND-LAPItpelaiqi 88  yellow fever mo...
XP_002426376  17 lSDEELQeAFAAGLIKPGLNIPC----EekELK--NNISGLKSKLKEFKL----NLNWIETLDVVST-PAPMppeaydev 85  human body louse
XP_001638992  13 DSDVELQkAFASGDLKVGLNKPAgfipRaqREP-FNNVEGLKRKYDQISQ----SLDWLERMDVTHK-PTADeendta-- 84  starlet sea ane...
XP_317941     31 DSDEELRqAFLRNELKPGLNVIL----KeeRQP-INDTIKLKAALETCTL----KAPWLERMDLVND-LAPLtpelaiqi 100 Anopheles gambi...
ESO05038      87 ----------------esdikgdGkEEENDFKLENLFYRQAQNAVLKGLARLTAFNIPTKRPEDYFAEMLKSDLHMKKVK 150 Helobdella robusta
KJE91077     129 -----------------------D-DAQDDFKREMSFYNQALEAVKLARPRLAAANIKFTRPDDYFAEMVKTDDHMRKVR 184 Capsaspora owcz...
8_pfamImport  65 ------------------vteddQtDVHNDFQREVSFYGQAQNSVISAMLRLHSSGINTKRPDDYFAEMAKKDDHMKKVG 126
XP_002415028  80 gelhl-----qkskkgkvvsgpdEdPVHHDFKREMTFYRQAQAAVLSGIPRLHQLGVPTKRPDDYFAQMAKSDDHMTKVR 154 black-legged tick
XP_001954735  88 ekheqkranlfkgnaklpyirpeEdPVLNDFKREMLFHRQAQSAVLEGIPRLHELGIKTRRPDDYFAEMAKSDEHMQKVR 167 Drosophila anan...
XP_001863228  89 ekheqkrenqfkgnkkipyvapeAdPVLNDFKREILFHRQAQAACVEGIRRFHDLGIVTKRPDDYFAEMAKTDEHMQRIR 168 southern house ...
Q16X80        89 ekheqkrenqfkgnkkipyvapeQdPVLNDFKREILFHRQAQAAVVEGIKRLHDLGVQTKRPDDYFAEMAKTDEHMQRIR 168 yellow fever mo...
XP_002426376  86 tkdqki---pklknyykfngafqSkDFTNDFKREMLFHRQAQSAILEGLPRLKSSGILTKRPDDYFAEMVKSDQHMHKVR 162 human body louse
XP_001638992  85 -----------------kdittpDpSVHDDFKREMMFYKQAQEAAKLGLLKLQKLRVSTKRPEDYFAEMVKTDDHMQRVR 147 starlet sea ane...
XP_317941    101 ekheqkrenlfkgnrkipyvkpeAdTVLNDFKREILFHRQAQAATLEGIGRLHELGIATKRPDDYFAEMAKTDEHMQRIR 180 Anopheles gambi...
ESO05038     151 ENILSLQAIKDKSEKAKKEREAKKVKKLADKEGRKEKKKEKleyKNTLKKVR--KKlnlgQRGKI--LNpddlFEDTSDR 226 Helobdella robusta
KJE91077     185 EALLSEHQAVERSEQAKKSRQMKQFGKKVQQQVLEDRQKQK---TSDLEAIKkfKK----DRSAKpdFL----DDGDDQF 253 Capsaspora owcz...
8_pfamImport 127 VKLLALKKRRETSEKNQNNFKLRKYGKQVQRAVTLERQQKK---REVLSSIKkfKKg---KITNTdfLDds--------- 191
XP_002415028 155 EKLLSKKTALERSEKARKLRELKKFGKKVQVEVLQKRQKEK---REMMDNLKkfKKg---QGS-LdfLEnt--------- 218 black-legged tick
XP_001954735 168 ANLMAKQQGQAKSERIKQIREQRKMGKMLAKQTKVQREAEK---KDMLDKLKkfRKg---KLKNLdfLEda--------- 232 Drosophila anan...
XP_001863228 169 KVLVAKQEGMAKSERARHLREQRRIGKLIQRQTQEKRDEER---RKTLNDIKkfRKg---KLSNLdfLDden-------- 234 southern house ...
Q16X80       169 KVLLAKQEGIAKSERARQLREQRRIGKLIQRQTTEKRDEER---RKMLDDIKkfRKg---KLSNLdfLDdde-------- 234 yellow fever mo...
XP_002426376 163 LNLQSRQTVIAQSERAKELRRLKKVGKKAQIETKLKQAEEK---RKLMNDVKkyRKg---LTKDLsfLDgkd-------- 228 human body louse
XP_001638992 148 SKLLSRQQAMERSEKAKKQREIKKYGKKVQQEVLEKRQKEK---KDMLEAVKkyRKg---KQTAPdfMKeddf------- 214 starlet sea ane...
XP_317941    181 KVLLDKQEGIAKSERIRQLREQRRIGKLIQREATEKRDEER---RKMLGDIKkfRKg---KLANLdfLDdddgp------ 248 Anopheles gambi...
ESO05038     227 kSVEVvyRKEqkikqqhkqqqqMNNNKNNNDSsyivpeKPMKANK----------K-----RMMKNKKFGFGGQKKRSKY 291 Helobdella robusta
KJE91077     254 -NIGVdkEES----------------------------HSQKTNS----------K-----RSYKNDKYGNGGKKRGSKR 289 Capsaspora owcz...
8_pfamImport 192 ---------------------sKENRPQGKKLsqlqklQKHKVNH----------K-----RNFRDKKYGFGGKKKGQKR 235
XP_002415028 219 --------------------grKGGPQRGKGG------TAPVPGQsrksltksqlK-----KQYKDKKYGYGGQRKRSKF 267 black-legged tick
XP_001954735 233 --------------------kaLESKQKQSAE-----------------------K-----RKQRNKKFGFGGKKKGLKR 264 Drosophila anan...
XP_001863228 235 --------------------eeGKPGGKRKAG------AKG-GGK----------KqlsgkRKARDAKFGFGGRKKGSKR 277 southern house ...
Q16X80       235 --------------------egGASKRKKKGT------VRGAGGK----------KqvnpkRAAKNAKFGFGGRKKGSKR 278 yellow fever mo...
XP_002426376 229 --------------------nnKSNSAKNKTK------LSAKSKK----------K-----RAAKDEKFGFGGRKKGSKR 267 human body louse
XP_001638992 215 -------------------dvnAESKSKGKPQ------QRNQINH----------K-----RKAKDKKFGFGGKKRNIKR 254 starlet sea ane...
XP_317941    249 -----------------rgefrKSGKGPGKGG------KGGKGGK----------GgasakRKARDAKFGFGGKKKGKKQ 295 Anopheles gambi...
ESO05038     292 NTRESVDEVQ-FKSFRSP------------AAiKKYKNKNKSNNRRNKKK 328 Helobdella robusta
KJE91077     290 NTRDSASDDSsFNFARNKalpkgfksagvaKKfGGGAGGKSKAPRPGKSR 339 Capsaspora owczarzaki ATCC 30864
8_pfamImport 236 NTNTSSNDVSgFKRKV---------------------HGNKKNVRPGKSK 264
XP_002415028 268 NTASSSADMGgFSRKK------------------HNTAPGKKNQRPGKAR 299 black-legged tick
XP_001954735 265 NTKSSSAGLDg-----EKs----------sRRqRGVKAGASVNKRLGKSR 299 Drosophila ananassae
XP_001863228 278 NTKESFMNDGn-----KKrk---------gPGgKGGAGGG-ANKRLGKSR 312 southern house mosquito
Q16X80       279 NDKKSFMGDGp-----KRkg---------gAAgGGGGAGG--KKRLGKSR 312 yellow fever mosquito
XP_002426376 268 NTKESSAYIGk-----M--------------SkKGKKTGFKTNKRLGKSK 298 human body louse
XP_001638992 255 NTQKSTSDVSsFNSRKHSk-----------APkPNKPGVKRKNQRPGKSR 293 starlet sea anemone
XP_317941    296 NTKESCMNDGp-----RRrg---------gPGgAKGGGGGGAKTRPGKAR 331 Anopheles gambiae str. PEST
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap