Conserved Protein Domain Family
Apc15p

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pfam05841: Apc15p 
Apc15p protein
The anaphase-promoting complex (APC) is a conserved multi-subunit ubiquitin ligase required for the degradation of key cell cycle regulators Members of this family are components of the anaphase-promoting complex homologous to Apc15p.
Statistics
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PSSM-Id: 399091
Aligned: 20 rows
Threshold Bit Score: 79.0174
Threshold Setting Gi: 74595371
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CCE65963      19 LALFRDIKTNI-------ALNENESNvskgsshqksrftfddlnQNGNASNk--kKmWSKYIVNKRKKRAQYYPPLAAYN 89  Tetrapisispora ...
CCE90883      14 LPLFRDIKEAL-------VLEKQQQS------------------KNGRPANeprmIkKNRGNEEELRSGRQYIPPLSAYN 68  Torulaspora del...
XP_003675861  25 LPLFQEVEENI-------RKGS-NSNsnngrsi-----rpiigwQDQKSGKnkkrF--------RRGEDNFYYPSLDSYN 83  Naumovozyma cas...
CCH57873      20 LSLFRDIKDEL-------LAEKQQQNtkkfv---------persRDTFSAS-------SQKGTIRPRTRYSFPLPLAAYN 76  Tetrapisispora ...
XP_001643679  18 LSIFRDIKDEL-------AKEQDKNNrn--------------glINGMKTEr--gGrKSGSRVCKSRDLCGGALPLAAYS 74  Vanderwaltozyma...
CAR27532      10 LPLFRDVKENL-------IQQRNEQQqq---------------hQQQQATH----QaKRRNHLKKSSTHHHYMPPLSAYN 63  Zygosaccharomyc...
Q6FU31        22 IALFEQIKEKL-------NRQQGLRHknnaahl-----rgqiglREGTVNN--------ESEDENQGDEAPYIPPLSAYS 81  [Candida] glabrata
Q5B2U7        13 HELWFGPQAVPssqqtepLSSSSSVSash--------------------------aqAARRHDSTQHRTGGTAPRLGASA 66  Aspergillus nid...
XP_007373902  12 YSLWNGVSSHP-------TLIPNESNesksnae-----pqtrstNNGVTTS-----------DQRKHINNLFAPPLSAYS 68  Spathaspora pas...
Q6BKN3        12 YKLWRHDDDGI-------DSSDFHRRtfnmhn-------anntnSNGATNTtnnnVtQEQLEDQRRHIRLLFAPPLLAYS 77  Debaryomyces ha...
CCE65963      90 TFDETPFIPqsrik-ygnaTGAKFDEMVMKEEMMKK---RLKDIQKLGWNFIRSIGVSKTMQQLEEEHK 154 Tetrapisispora phaffii CBS...
CCE90883      69 AIEEVPYFPfgv-----deRERRFDELTMRMDQTQR---RLKSIRTLGWNSFRPIGVNETMQQLKEKSM 129 Torulaspora delbrueckii
XP_003675861  84 VFNVKPYYC----------RGGQMDPFRMRLDQQRH---AFKGIRHLGENFFRPIGVYKTVNEMKLDQE 139 Naumovozyma castellii CBS ...
CCH57873      77 PFDEMPFYfsr------nrRNRRFDEAQMKLEQYRR---NKRAIRNLGKDYFRPIGLNKTMRQIEEERL 136 Tetrapisispora blattae CBS...
XP_001643679  75 VFEETPFYSrsc----rghRNGKFDVLYMREEQLKR---NKNAIRYLGWNYIKVMGLNKTMCQLEEERK 136 Vanderwaltozyma polyspora ...
CAR27532      64 ASEERPYYP-----------GGRFDEMTMRIEMEQR---RLNGIRNLGYNYIRPIGVGHTLQMIRERKQ 118 Zygosaccharomyces rouxii
Q6FU31        82 ATSDEPYLPlrs----ikkGCFKVSIAAMKYDDFER---RMYQIRKTGWHTLKPIGVAKTMAEIRREQR 143 [Candida] glabrata
Q5B2U7        67 LATSDT-----------------LAALILEERALRA---RKNNIASFGCSWIKPAGCPKTMLGMKEEEA 115 Aspergillus nidulans
XP_007373902  69 A--NYPGACsfqleytmrrGTQHNSKMFSITPSTQAnieQLDVIRNYGYNTIRPIGINKTMEEIEFENs 135 Spathaspora passalidarum N...
Q6BKN3        78 A--EYPGASlsqleytisnQSGNKQDLPLLTPLIQRkldRLQQIRNIGYTSIIPAGVGKTMEQIDFEEA 144 Debaryomyces hansenii
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