Conserved Protein Domain Family
Tcp11

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pfam05794: Tcp11 
T-complex protein 11
This family consists of several eukaryotic T-complex protein 11 (Tcp11) related sequences. Tcp11 is only expressed in fertile adult mammalian testes and is thought to be important in sperm function and fertility. The family also contains the yeast Sok1 protein which is known to suppress cyclic AMP-dependent protein kinase mutants.
Statistics
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PSSM-Id: 399067
Aligned: 210 rows
Threshold Bit Score: 149.312
Threshold Setting Gi: 301099263
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_007329793  179 LRHDILFDSALQFRpAGH-----------RRKKENVERYWDAVAREIESgctcvsydtssrryipticvcdrvplptdap 247  Agaricus bisp...
XP_010239936  659 MVNEMLHKNGVAFAgKSDaastvekdlqtKLREAMEKAFWDVLTDSMRG------------------------------- 707  stiff brome
XP_004975681  642 MVNEMLHEDDSAFAgRSDsantaeeefqkKVRETMEKAFWDSVTDSIRG------------------------------- 690  foxtail millet
Q7XQG9        317 MLNEMLHEDDVSFGgNSDnvssaekefqaKVKSTMEKAFWDLVTDSMKG------------------------------- 365  Japanese rice
XP_006648736  684 IVNEILHDF---IAd--NnienveggfkeKVRETMEKAFWDVVMDSLRG------------------------------- 727  malo sina
XP_008678693  725 IVNEILHDIHGSFAdISDgagtvegdfkvKVKETMEKAFWDVVADSMRG------------------------------- 773  Zea mays
KRH44072      684 LVNEFLHEHHYSVTdEFDvsdhiqnsvegKIKQTMEKAFWDGIMESVEV------------------------------- 732  soybean
O23129        658 MVNEFLHDGNLNFPgGSTvkdee-dnlkrRIKETMERAFWDNVMESMKL------------------------------- 705  thale cress
XP_009115579  649 IVNELLHDWDFKFPgDEEdsl------krKVKETMEKAFWDSVMESMKL------------------------------- 691  field mustard
XP_015691466  653 MVNEMLHEDG-SFAgNSDhisaaekdfqaKVKATMEKAFWDVVTDSMRG------------------------------- 700  malo sina
XP_007329793  248 ltftippsyiTVRTPSRVRALLNEFLEVLLHVIqplatlsgpyvksevlqgpveeHAEQAKHIRSLFDLDLIEQELKHGV 327  Agaricus bisp...
XP_010239936  708 ----------DKPDYSQLINLVKEVRDSLHDLA----------------------PKEWKEEILANIDIEILSQVLESGS 755  stiff brome
XP_004975681  691 ----------DMPDYSRLINLVKEVRDSLHELA----------------------PKEWKEEILENIDIEILSQVLGSGS 738  foxtail millet
Q7XQG9        366 ----------DKPDYTQLINLVKEVRDSLHELA----------------------SKELKEEILENIDLEILSQVLESGS 413  Japanese rice
XP_006648736  728 ----------DMPDYSYLVQLVKEVGDALHEMA----------------------PKGWKEEITNNIDLEILSQVLESGT 775  malo sina
XP_008678693  774 ----------DMPDYCYLVSLVKEIREALEELS----------------------PTGWKEEISDNINLEILTQLLESGS 821  Zea mays
KRH44072      733 ----------DHPNYDRIVQLMGEVRDEICEMA----------------------PKSWKEDIFAAIDLEILLQVLKSGN 780  soybean
O23129        706 ----------EKPDYSCISNLMKEVSDELCQMV----------------------PDSWKVEITETIDLDILSQLLNSGT 753  thale cress
XP_009115579  692 ----------EEPDYSCISNLMREVRDELCQMV----------------------PDTWRVEITETIDLDLLSQLLNSGC 739  field mustard
XP_015691466  701 ----------DKPDYTHLINLVREVRDSLHELA----------------------SKGLKEEILENIDIEILSQVLEAGS 748  malo sina
XP_007329793  328 FDPS---GLFQVIGLTLKNHCAPMRDHAVDSMVeAAKacapg---------gsatiRdAVKVVRNCSEILELMKLDIANH 395  Agaricus bisp...
XP_010239936  756 QDTQylgQILHYSLAMVRKLSAAAKEDEMKKSHeKLLselaassevnndkaissfvIaVIKGLRFTLEEIKELQVEVSKA 835  stiff brome
XP_004975681  739 QDAQylgQILQYSLAMVRKLSAAAKEDEMKKSHdKLLselaassev-ndnginsfvIaVIKGLRFILEEIKELQAEVSKA 817  foxtail millet
Q7XQG9        414 QDTRylgQIMHYSLDMIRKLSAPAKEDDMKRSHeKLLnelaassev-ndngissfvIaVIKGLRFTLEEIKQLQSEVSKA 492  Japanese rice
XP_006648736  776 QDIQylgQILHYSLGVLRKLSSPAKEDEMKRSHdKLLgeltvhtec-nnggpnsfvIaVIKGLRFTMEELKALKADVSRA 854  malo sina
XP_008678693  822 QDRQylgQILQYSLDKLRKLSSPVKEHEMKKSHdTLLgelvedsks-nykdpnsfvLcVIKGLRFTMEELQALKTEVTRA 900  Zea mays
KRH44072      781 LDIDylaKILEFSLVSLQKLSAPANEEMMKAAHkKLFhelseichs-rdesnnscvVaLVKGLQFVFGQIQILKKEISKA 859  soybean
O23129        754 LDIDylgKMLEFALATLRKLSAPANDRENESTHrDLLkelhrlcea-edesgnfraVaIVKGIRFILEQIQELKREIGIG 832  thale cress
XP_009115579  740 LDIDylgKMLEFALATLRKLSAPVNDRENESTHqSLLeelhrlcqa-kdesgnlhaVaIVKGIRFVLEQIQELKREIGLG 818  field mustard
XP_015691466  749 LDMRylgQILHYSLDMVRKLSAPAKEDDMKKSHeKLLnelaasseg-tdngtnsfvIaVIRGLRFTLEEIKQLQTEVSKA 827  malo sina
XP_007329793  396 QMQTLRPFLVYSS-GAFERKMLRSRRsi----dPSLPLTKEWLRFAhtTFSSQEEPIKYPSqpqglry------------ 458  Agaricus bisp...
XP_010239936  836 HIQLMQPMITGSAgVEYLQKAFNDRYgppanasSSLPLTLQWVSTS--KNIVEEEWSEHLGalsvlpaadhaqplvtvlr 913  stiff brome
XP_004975681  818 RIQLMQPIIKGSAgVEYLQKAFTDRYgppdnasASLPLTMQWISTS--KNIVEEEWSEHSDclsiipsagqapalvpvlr 895  foxtail millet
Q7XQG9        493 RIQLMQPIIKGSAgVEYLQKAFADRYgppanasASLPITKQWVSAT--KSIVEQEWSSHLEslqalpadhaqrvvvpalr 570  Japanese rice
XP_006648736  855 RIQLLEPIIKGSGgVEYLQKAFADRYgspsnasAALRSTALWISTS--KDTVEVEWNEHINsfsilpatdnaqplvatlr 932  malo sina
XP_008678693  901 RIQLLEPLIKGSGgVEYLQKSFAGRCgspsdalASLPSTARWIFSL--KDVVEEQWNEHVSslsilpeadhvqtlvatlr 978  Zea mays
KRH44072      860 RIRLMESLVKGSAgLDYLRNAFANKYgspsdanTSLPSTLRWISSV--WNCKDQEWEEHVSsssalasnssqewlpsttl 937  soybean
O23129        833 RIAIMKPFLQGPAgFDYLTKAFEKRYgpptqayESLPVTRRWISTL---LSSKEEWEEHNNtlsalnvverssmgislkt 909  thale cress
XP_009115579  819 HITMMKPFLKGPAgFDYLTQAFEKRYgpstqahGSLPATRRWISTL---SSCKDEWEEHINmlsalnvversssmgislk 895  field mustard
XP_015691466  828 RIQLMQPIIKGSAgVEYLQKAFADRYgppldtsASLPITKQWISAT--KNIMEQEWSEHLDalevlpagdnaqrlvtvlr 905  malo sina
XP_007329793  459 ----------------------------tslgkkhQLYISVVRSIVDMVFDppSSsSPSlvtttlpsppsdlpfpsFPET 510  Agaricus bisp...
XP_010239936  914 sghg--------apgpqaaslsaagssglpeckgdKIDKLVRIGLLQLISGmeGLqLQS-----------------TPES 968  stiff brome
XP_004975681  896 aghg---------tpveqpsssaagasgqpeckgeKLDKLIRIGLLQLITSmeGLqMQS-----------------TPES 949  foxtail millet
Q7XQG9        571 aghg---------apmaqasssaasgsglpeckgeKIDKLTRVGLLQLISNveGLnMQS-----------------TPET 624  Japanese rice
XP_006648736  933 sghg--------vpdqqqstipaaddlelpeckgeRLDKLIRIGLLQLISGieGVqMQS-----------------IPET 987  malo sina
XP_008678693  979 tgha---------vagvqsvipaadntglpecrgeILGKLIRIGLLQLISSmeGVeRES-----------------VPET 1032 Zea mays
KRH44072      938 rtggsillkttgspmafspdsanakgdqqpeckgeQLDLGVRLGLLKLVSGisGLtQDD-----------------LPET 1000 soybean
O23129        910 ggsfl------spvnttskstvmdtagqlseckgeRVDLAVRLGLLKLVNQvaGLtPEV-----------------LPET 966  thale cress
XP_009115579  896 tggsfl-----statssqstvadtaegqvleckgeRVDLTVRLGLLKLVSQvsGLtLQV-----------------LPET 953  field mustard
XP_015691466  906 aghg---------apgtqtslsaasssdlpeckgeKFDKMIRVGLLQLVSGmeGLqMQS-----------------TPES 959  malo sina
XP_007329793  511 LYLDQARIQTYTSEIADLVALWMFLLLYRQLi--sSFGHRkyqkerINEFASILKREIRAIGPRslhtcflecsnssgsn 588  Agaricus bisp...
XP_010239936  969 FHLNFMRLRAVQGQFQEVIVMATSMLVLRQVlmseNSKITpl---eLENVISELFGTLVKLLDS---------------- 1029 stiff brome
XP_004975681  950 LQINLLRLRSVQSQFQKVIAIATSMLVLRQVlmseNSEATpl---eLENAISELFKALEKILDS---------------- 1010 foxtail millet
Q7XQG9        625 FQINLPRLRAVQDQFQKVIVIATSILVLHQVlv---skVAap---eLQNAISELYDALVKLLDS---------------- 682  Japanese rice
XP_006648736  988 FKLNWLRLRSVQSQFQQVIVIATSMLVQRQVlatdDPSITpt---eLENATSELFNALTELLDN---------------- 1048 malo sina
XP_008678693 1033 FMLNWLRLRSVQSKFQQVIVIATSMLVLHQVlaseNPKITss---eLENATSELFNVLTRLLDN---------------- 1093 Zea mays
KRH44072     1001 LSLNFLRLRSVQAQIQKIIVISTSILIRGQVllseKAVANpa---dMENLLSKCAAQLLDLLNR---------------- 1061 soybean
O23129        967 FQLNLFRVRDIQAEIQNIIVVTTSLLIWRQMla------------ksESETESMAKKLLELLDG---------------- 1018 thale cress
XP_009115579  954 FLLNLSRLRGTQAEIQKITVVTISLLIWRQMlaseRIVK-------SETETETMAKKLLDLLDG---------------- 1010 field mustard
XP_015691466  960 LQLNLVRLRAVQEQFQKVIVIATSMLVLRQAlmskNSKITpp---eLENTISELFDALVKLLDH---------------- 1020 malo sina
XP_007329793  589 qnpttdklksalDNV--VLQIARRassiQRGQElPEIGALPsmtddipskfTVSVARKWVDANMKL----HSSLRKLlhg 662  Agaricus bisp...
XP_010239936 1030 ------------SPEagTEEIVEA----MMSSSaSAGSVSd---------eKIQSRRQIITRVLLKslqdGDVVFKK--- 1081 stiff brome
XP_004975681 1011 ------------SPDagTEEIVEA----MISASaSVGSPSe---------eKIQARRQMITRVFLKslqpGDVVFKV--- 1062 foxtail millet
Q7XQG9        683 ------------NPDasTEEIVEA----MASSLaTVGSLSLpe-------kQAQATAELATKMLLKslqaGDVVFGK--- 736  Japanese rice
XP_006648736 1049 ------------FANasTAKIMEA----MIRSStSTAGSTSsd-------eITESRKQMLTRVFLKslqtDDAVFKK--- 1102 malo sina
XP_008678693 1094 ------------FPDvgTEKIIEA----MMYSStSRSLSDHe---------RMNARKEILTRVFLRslqtDDTVFKK--- 1145 Zea mays
KRH44072     1062 ------------VEDadIEDIVEV----LCNFPtVEVEDTG----------KLESRKVVAASMLGKslqaGDVVFER--- 1112 soybean
O23129       1019 ------------KEGagLTEIIET----TMSE-------------------EDGEKKKMMRGLLGKslgeGNTVYER--- 1060 thale cress
XP_009115579 1011 ------------KEEagLMEIVET----TMSEE------------------GDERKKMMMRGLLRKsleeGNTVYER--- 1053 field mustard
XP_015691466 1021 ------------NPEagTSEIAEA----MASSLaSAGSLPDe--------qQIQATKELATKMLLKslqaGDTVFGK--- 1073 malo sina
XP_007329793  663 rLKKvvfervladvyparseaalekmmgkeiegwgevllpskdclgialpksaipfsdnkapaqedgmgnglemlsdevq 742  Agaricus bisp...
XP_010239936 1082 -VSRavhcafrgvvlggsgmkgqk-------------------------------------ladaalrrvgagkladrvv 1123 stiff brome
XP_004975681 1063 -VSRavycafrgvvlggsspkgqk-------------------------------------ladaamrrigavklvdrvv 1104 foxtail millet
Q7XQG9        737 -VSRtvycafrgvvlggggvkgkk-------------------------------------laeaplrrlaaakladrvv 778  Japanese rice
XP_006648736 1103 -VSRsvycafravtlgglgggargr-----------------------------------klgngalrrigatkltgrvv 1146 malo sina
XP_008678693 1146 -VSQsvycafravtlggsgekgrm-------------------------------------ladaslrrvgatkltarlv 1187 Zea mays
KRH44072     1113 -VFNavysalrgvvlggsgirgrk-------------------------------------laemalmkvgagiltdkvv 1154 soybean
O23129       1061 -VTSciykaargallagngengkr------------------------------------mvetemkkvggggglkervl 1103 thale cress
XP_009115579 1054 -VTGciykalrgvllagngengkrvv--------------------------------eremkkvgvgggsggglkervi 1100 field mustard
XP_015691466 1074 -VSQavycafravvlggggargrklaeaplrrvgaag------------------------------------------- 1109 malo sina
XP_007329793  743 SLVEKISLLVVVHFNAYLPVYEKEEF 768  Agaricus bisporus var. burnettii JB137-S8
XP_010239936 1124 KASEVLIMVATVTEKVHGPWYNALA- 1148 stiff brome
XP_004975681 1105 KAAEVLIKVATVSEKVHGPWYKALM- 1129 foxtail millet
Q7XQG9        779 KAGEMLINMAVISEKVHGQWYKALAL 804  Japanese rice
XP_006648736 1147 KTAGVLIRAATISEQVHGPWYSHLL- 1171 malo sina
XP_008678693 1188 KAAEVLIKAAMVSEQVHGPWYTQLL- 1212 Zea mays
KRH44072     1155 ETAGVLIVAATISVSVHGPWYKHLTD 1180 soybean
O23129       1104 ETARALGVVACVSVRVHGPWLTQLMP 1129 thale cress
XP_009115579 1101 ETGRVLGVVACVSVRVHGPWLAHLMQ 1126 field mustard
XP_015691466      --------------------------      malo sina
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