Conserved Protein Domain Family
YL1

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pfam05764: YL1 
YL1 nuclear protein
The proteins in this family are designated YL1. These proteins have been shown to be DNA-binding and may be a transcription factor.
Statistics
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PSSM-Id: 399054
Aligned: 114 rows
Threshold Bit Score: 45.4836
Threshold Setting Gi: 121979862
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ERS97816       66 RAKRATAGNRMKSLIASVAAaaggdlsgsgtgggrgtpedADDLEL--------LFAD---------------DGEDAGW 122  Sporothrix sc...
EFC41925       16 LPSRSTRGKRLTELE-------------------------GIDKDVddefwkmnMFAE---------------DEGDNEF 55   Naegleria gru...
Q23RD9        472 MTFRSRRGEGIKKLMELQKRne----------------gfGDDLDD--------FWKEnkyfgkitevtkandEEEDEDF 527  Tetrahymena t...
EEA05396       92 LPNRSSRGRRYTQLV-------------------------GEEAERdtqfwghnTWEE---------------EECDSEW 131  Cryptosporidi...
Q5CQ02         66 lPERASRGKRYTQLL-------------------------GEEEEKdvkfwghdTWEE---------------EEEDSGW 105  Cryptosporidi...
Q8IKJ7         93 LPQRKNRGKNMKKLI-------------------------GEDLEKdeqfwndsIWEE---------------EEIDEEY 132  Plasmodium fa...
Q7RG66         86 MPKRKNRGRNLKKLI-------------------------GEDLEKdekfwndsIWEE---------------EEIDEEY 125  Plasmodium yo...
XP_001615747  121 MPKRKNRGKNLKKLI-------------------------GEDLEKdekfwndsIWEE---------------EEVDEEY 160  malaria paras...
XP_002260226   92 MPKRRNRGKNLKKLI-------------------------GEDLEKdekfwndsIWEE---------------EEVDEEY 131  Plasmodium kn...
XP_001609681   69 LPKRETRGKKYTQLL-------------------------GEELEKdqqfwghnTWEE---------------EAVDEDY 108  Babesia bovis...
ERS97816      123 SLDEDGEDGSddgdvddgddddddagrgnktaaktkgrrrrrddddaenDDen-----mdTSD-DdddddddgqgGGEGA 196  Sporothrix sc...
EFC41925       56 ETTEQILEEEqd------------------------------------yEDsdmdeytsdEEGeQq--------rANNVE 91   Naegleria gru...
Q23RD9        528 NEEEFKDVKDv--------------------------------------FDsdfqdtsdlEDDgDd--------dSNMSD 561  Tetrahymena t...
EEA05396      132 SSINQDEES----------------------------------------EEsssessqseDNAdEef-------vEIEDE 164  Cryptosporidi...
Q5CQ02        106 SSEDEKVELEilgg-------------------------------edtsTDsendsqsddGMEeEme------amAEDDD 148  Cryptosporidi...
Q8IKJ7        133 VNSEGEDEYVd-------------------------------------iTDsd-----fdDDEdNe---------eDEEE 161  Plasmodium fa...
Q7RG66        126 VNSEGEEEYVd-------------------------------------vTDsd-----fdDDEdDa---------eGDDE 154  Plasmodium yo...
XP_001615747  161 VNSEGEEEYId-------------------------------------vTDsd-----fdDDEdEv--------dDDDEE 190  malaria paras...
XP_002260226  132 VNSEGEEEYId-------------------------------------iTDsd-----fdDDEdEv--------eDDDEE 161  Plasmodium kn...
XP_001609681  109 NCSEGEEQYAy-------------------------------------sTDsd-----fdDPEtDk-----------sDE 135  Babesia bovis...
ERS97816      197 DDLAGER--------ELE---RKEREKRna------aRKRkaqaai------parfrKKVRIdqpektaagaagaaagrg 253  Sporothrix sc...
EFC41925       92 KKIAKEE--------------RETKKRKnvykdesksKKKkstdksaastvekqpktPKA-------------------- 137  Naegleria gru...
Q23RD9        562 EDSDSEK--------K---------------------KKRnkdkpsylmkkddvirkEQE-------------------- 592  Tetrahymena t...
EEA05396      165 DDGLSYK--------------DSSRKNKai-----ykGKYkdpslfsksmqknllkrQNK-------------------- 205  Cryptosporidi...
Q5CQ02        149 DDDVIDG--------------KKPKKPKrm-----fsGKYkdpslflksaqkemlkkARK-------------------- 189  Cryptosporidi...
Q8IKJ7        162 EVDDDEQnkrgarrhSIEyeeRKNNNKKnfayleklkKEKqnkimkynlmkqkqnelKKN-------------------- 221  Plasmodium fa...
Q7RG66        155 DEEQNEN--------EGDdddSKRKKKKiyaymenlkKKKmlkynlm---kkrkydnMKNS------------------- 204  Plasmodium yo...
XP_001615747  191 EAERNER--------ELDdeeVKWKKKKmfsyleklkKQThnhalrhklmkkakyygSKVLG------------------ 244  malaria paras...
XP_002260226  162 EVERNEK--------ELDdeeVKRKKKKmfsyleklkKQThnnalrqklmmkakhygSKARG------------------ 215  Plasmodium kn...
XP_001609681  136 EVDESYL--------------KEKKTRKhgsyvdpalKRQqiakrdirrqnvtkstpPERk------------------- 182  Babesia bovis...
ERS97816      254 grggrrrapgsvsasggstptpsatptPGfpssqPP--PP--RKKKKS-ERAsWLPT-AAD-------MPV--------- 311  Sporothrix sc...
EFC41925      138 ----------------------------------------------------------------------Pktpktt-lp 146  Naegleria gru...
Q23RD9        593 --------------------------------------KIakQRQKQKaERLkQLDTqEENeiqisqkIQKekreaqiti 634  Tetrahymena t...
EEA05396      206 ------------------------------------------------------------Tkkk--vkNTSsskpkefqi 223  Cryptosporidi...
Q5CQ02        190 ------------------------------------------------------------Kasg--ikKTGivkkspaal 207  Cryptosporidi...
Q8IKJ7        222 ----------------------------K------QliSNksKKSEDDaEEEqKEEViKTKeqlkeerRLKkkkkleqay 267  Plasmodium fa...
Q7RG66        205 ----------------------------Ks----INdiRDqtDDKKNQeNKKq-----------------Rkrkkneqsy 235  Plasmodium yo...
XP_001615747  245 ---------------------------GKyg-apLHgvEHksGRRKKGvADEgAADE-EVAgalkvegMVKkqkkvdssc 295  malaria paras...
XP_002260226  216 ---------------------------GKhg-taLHgvEHksGKKKKGeGEAeAEEA---Lei---qgTVKkrkkvdtps 261  Plasmodium kn...
XP_001609681  183 --------------------------------------------------------------------IKTkefatqgne 194  Babesia bovis...
ERS97816      312 ---RASSRTTTRTS----KEQLYQQMAER-ERR-------RERQLA--IMAKKAARDEAnKKp-pLTQAERLAEAAIVEE 373  Sporothrix sc...
EFC41925      147 vemKRSSRQSTVKA----TEATDEKIKAKtSKT---------------------KTPKApKElkkFTQEELLEEAKITTE 201  Naegleria gru...
Q23RD9        635 qleKRTLRQSTNEKsllsQSQLSPRLKKKlRLNedgsvdiNGQQGEqgGQAQGAGGKKKrYIhdfLTQEQLLKEAVFTEF 714  Tetrahymena t...
EEA05396      224 eerSMSVRKSTAKK----KQDLQEEMRRRdEEA----------IERarLRRKKRNHDESnRLpkeMTQEERIAQSKIVEK 289  Cryptosporidi...
Q5CQ02        208 eprTMSVRASTTQK----KQDLQESIKRRdEEA----------QDRtnRKRLKKSSTSKeQAktvMTQEERLEACKEIEK 273  Cryptosporidi...
Q8IKJ7        268 lylNRSTRDTTRRKteymEKVFEMRKIKK-ENR---------------FKKFGARRREKkNMqreMTREERLEEAKITEQ 331  Plasmodium fa...
Q7RG66        236 imiHRSTRDTTRQKteqmEKKFELRRIKK-EDR---------------FKKFYENRQKKkGMqreMTREERLEEAKITEQ 299  Plasmodium yo...
XP_001615747  296 mvlHRSTRDTTRQKteqiQKLSELRRIKK-ENR---------------FKKIYENKKKQkSMqreMTREERLEEAKITEQ 359  malaria paras...
XP_002260226  262 mvlNRSTRDTTRQKteqiQKLSELRRIKR-ENR---------------FKKMYENKKNKkSTqreMTREERLEEAKITEQ 325  Plasmodium kn...
XP_001609681  195 vltDRSVRASTKIKtkaaNEMERKRDLIKtEMS------------------AGAAHKRQeTKkkhLTQEQLMEMALKNEA 256  Babesia bovis...
ERS97816      374 ANARSLNTWEEAEKQREaeRAaKL-AAMYNRTLeGPVVTFWS 414  Sporothrix schenckii ATCC 58251
EFC41925      202 ENKKSLLKLRQTEEDVKkkARdSKsKMIDPY---EPRVKYIS 240  Naegleria gruberi
Q23RD9        715 VNRKQLEDLLRLEEEKKqfSLsKK-FIDE-----GPKIIYkn 750  Tetrahymena thermophila SB210
EEA05396      290 MNTESLSYLEACEEQKRylDNtSA-SVRKQFQS-GSLNIYIS 329  Cryptosporidium muris RN66
Q5CQ02        274 MNIESLNQLEAFEEHKRylDNtSA-SIRKQLQS-GSLNIYIS 313  Cryptosporidium parvum
Q8IKJ7        332 YNIQSLLQLQAWEEEKKkyIEnKK-VIHY-----KPQNVFIS 367  Plasmodium falciparum 3D7
Q7RG66        300 YNMQSLLELQAWEEEKKkyVEnKR-IIYH-----KPKNVFIS 335  Plasmodium yoelii yoelii
XP_001615747  360 YNLQSLLQLQAWEEEKKkyIEnKR-IIYH-----RPENVFIS 395  malaria parasite P. vivax
XP_002260226  326 YNLQSLLQLQAWEEEKKkyIEnKR-IIYH-----RPKNVFIS 361  Plasmodium knowlesi strain H
XP_001609681  257 ANTRSLEKMKAWEDEKKyyEEiKK-WNYK-----GNYDIWvc 292  Babesia bovis T2Bo
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