3WIN,2E4M


Conserved Protein Domain Family
Botulinum_HA-17
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pfam05588: Botulinum_HA-17 (This model is not part of the current CDD release)
Clostridium botulinum HA-17 domain
This family consists of several Clostridium botulinum hemagglutinin (HA) subcomponents. Clostridium botulinum type D strain 4947 produces two different sizes of progenitor toxins (M and L) as intact forms without proteolytic processing. The M toxin is composed of neurotoxin (NT) and nontoxic-nonhemagglutinin (NTNHA), whereas the L toxin is composed of the M toxin and hemagglutinin (HA) subcomponents (HA-70, HA-17, and HA-33).
Links
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Statistics
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PSSM-Id: 516877
Aligned: 4 rows
Threshold Bit Score: 204.426
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3WIN_C  24 SAERTFLPNGNYNIKSIFSGSLYLSPVSGSLTFSNESSANNQKWNVEYMAENRCFKISNVAEPNKYLSYDNFGFISL--- 100 Clostridium botulinum B
O06016   2 TAERTFLPHGNYKIKSIFSDSLYLTPLSEIITFLNTSSENNQKWKLQYVEEKNAYKISNIAQPDKYLTYNSSQFIVLkni 81  Clostridium botulinum
Q9LBT0   2 SSERTFLPNGNYKIKSLFSNSLYLTYSSGALSFSNTSSLDNQKWKLEYISSSNGFRFSNVAESNKYLAYNDYGFIYL--- 78  Clostridium botulinum
2E4M_C   2 SSERTFLPNGNYKIKSLFSDSLYLTYSSGSLSFLNTSSLDNQKWKLEYISSSNGFRFSNVAEPNKYLAYNDYGFIYL--- 78  Clostridium botulinum

3WIN_C 101 -DSLSNRCYWFPIKIAVNTYIMLSLNKVnelDYAWDIYDTNENILSQPLLLLPNFDIYNSNQMFKLEKI 168 Clostridium botulinum B
O06016  82 gDSTALENYWIPYKIASNTYIITNLKEY---DKAWDIYDLNGDISDQPLLLQQLFYYEKSNQMFIFEKI 147 Clostridium botulinum
Q9LBT0  79 -SSSSNNSLWNPIKIAINSYIICTLSIVnvtDYAWTIYDNNNNITDQPILNLPNFDINNSNQILKLEKL 146 Clostridium botulinum
2E4M_C  79 -SSSSNNSLWNPIKIAINSYIICTLSIVnvtDYAWTIYDNNNNITDQPILNLPNFDINNSNQILKLEKL 146 Clostridium botulinum
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