Conserved Protein Domain Family
SRP9-21

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pfam05486: SRP9-21 
Signal recognition particle 9 kDa protein (SRP9)
This family consists of several eukaryotic SRP9 proteins. SRP9 together with the Alu-homologous region of 7SL RNA and SRP14 comprise the "Alu domain" of SRP, which mediates pausing of synthesis of ribosome associated nascent polypeptides that have been engaged by the targeting domain of SRP. This family also contains the homologous fungal SRP21.
Statistics
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PSSM-Id: 398894
Aligned: 96 rows
Threshold Bit Score: 63.3704
Threshold Setting Gi: 406701679
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CCE32263       4 FKTSQEWLEKSSLLIEARPKTTRVTTRYSIKpapAGKQPKSTTtttasptttatttttttttttitpsstpsdaaaraas 83  Claviceps purpu...
CCK68293       3 IKPIDTFITNGVRLFEVNPSQSAFSITYKPP---VVKSDKGAEkkv---------------------------------- 45  Kazachstania na...
CCF57953       3 VKPIDTFIVNGIRLFEINPSQSTISITYNPK---NGKKE----------------------------------------- 38  Kazachstania af...
Q6FM21         3 VKPIDTFIENSVKLFEANPSGSSITISYHGGa------------------------------------------------ 34  [Candida] glabrata
XP_003672574   3 VKPIDTFITSSVKLFEVNPSQTTFTISYRGP---SDTDNNK--------------------------------------- 40  Naumovozyma dai...
CCC66997       3 VKPIDTFITSSVKLFEVNPSQTVISLTYKTP---TEKK------------------------------------------ 37  Naumovozyma cas...
XP_003686568   3 IKPVDLFISNSVKLFEVNPSQTTISLTYKFL---EKKKN----------------------------------------- 38  Tetrapisispora ...
XP_001645608   3 IKPIDSYISNSVKLFEVNPSQTVFSLTYKFP---KNSNN----------------------------------------- 38  Vanderwaltozyma...
XP_002498115   3 VKPIDSFISQSVGLFEANPSQTTFAISYKNR---LPAQL----------------------------------------- 38  Zygosaccharomyc...
CCE89557       3 VKPIDTFITNSVQLFEANPSQTIFSISYKCK---SKSTQ----------------------------------------- 38  Torulaspora del...
CCE32263      84 tpkpPRGSIVLTTYDPVTGVNLKYRTTKAAEVSRLVqAALGRLGRCM 130 Claviceps purpurea 20.1
CCK68293      46 --skKCTKVAFRFNNAHLATNYSFDTNKSKDVSRLL-NSLGPRGVSI 89  Kazachstania naganishii CBS 8797
CCF57953      39 ----KSSNVSFKIHNPHLNTNYKFRTNKSKDVSKLL-NSLGPRGVTi 80  Kazachstania africana CBS 2517
Q6FM21        35 ----KADPVVFRTHNPHLSTTYKYQTKMNKEVSRVL-NALGPRGVSM 76  [Candida] glabrata
XP_003672574  41 ----KKTSVSFRSHNAHLGVSYKFNTNKSKDVSRLL-NAIGPRGVSI 82  Naumovozyma dairenensis CBS 421
CCC66997      38 ----RQSDVIFKTHNPHLGTSYKFSTNKSKDVSRLL-NAVGPRGVSV 79  Naumovozyma castellii CBS 4309
XP_003686568  39 ------STVTFKTNNPHQSTNYKFQTNKSKDVSRLL-SAMGPKGVTI 78  Tetrapisispora phaffii CBS 4417
XP_001645608  39 ------CTVKFNTHNSHLSSNYNFKTCKSKDVSRLL-SAIGPRGVTV 78  Vanderwaltozyma polyspora DSM 70294
XP_002498115  39 ------PQVSFKTHNPHLNCHYKFQTCKSKDVSRLL-SALGPRGVTV 78  Zygosaccharomyces rouxii
CCE89557      39 ----KKPVVSFKTHNSHLSNHYKFKTNKSKDVSRLL-SALGPRGVSI 80  Torulaspora delbrueckii
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