4XIN


Conserved Protein Domain Family
Myco_19_kDa
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pfam05481: Myco_19_kDa (This model is not part of the current CDD release)
Mycobacterium 19 kDa lipoprotein antigen
Most of the antigens of Mycobacterium leprae and M. tuberculosis that have been identified are members of stress protein families, which are highly conserved throughout many diverse species. Of the M. leprae and M. tuberculosis antigens identified by monoclonal antibodies, all except the 18-kDa M. leprae antigen and the 19-kDa M. tuberculosis antigen are strongly cross-reactive between these two species and are coded within very similar genes.
Links
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Statistics
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PSSM-Id: 516832
Aligned: 37 rows
Threshold Bit Score: 53.8832
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4XIN_A        12 PAQLSSTASVTVDGKDrN---FHIVTCRQLEWRRMIDIGA---D-FSGAKVAVDeN----A-QPPVVESVHIQNL-S-GF 77  Mycobacterium a...
2_pfamImport   1 SALGDSTAEVKINGEAaGg--PYPVTCSQNGWAWTVQTQQ---Q-DTGFTAVFD-T----E-PEMTAQSVEITGL-N-GF 66 
EID13406      26 ETVPQKTARITVDGNTrT---SHAVSCTQVEWLMTVDIGA---A-PGNVQAMLRlQ----S-DDPKAESVNINNV-N-GF 91 
WP_047314137  24 ETIPRRAAHLTIDGNThS---TRSAACSQDQSYRTINIRE---S-GGQVEAVVLfS----G-GRAIAQWVMIRNV-D-GF 89  Mycobacterium h...
O07750        26 QTVPRKAARLTIDGVThT---TRPATCSQEHSYRTIDIRN---H-DSTVQAVVLlS----G-DRVIPQWVKIRNV-D-GF 91  Mycobacterium t...
EID11904      17 QIVPRKAARVTVGGRTyT---SRAPRCSQLQSFWTIEAAG---P-RGHVEAVVLlH----G-DRVIPQWVKISGF-D-GF 82 
WP_038549894  77 GGDGGSVATLVFDGTDlAsqfTN-VQC-REDGSDEFEIDlwndDrTDHVEVDLDvR------DQPRVDGLGVDR------ 142 Corynebacterium...
WP_019512813  48 DSVPAGTAQVVVNGAPgP---TGPVQCDDAAGPLTISIG----EsSLGVTVIIDePddeaGqDAPAVRSVTIGDV-G-GV 118 Mycobacteriaceae
WP_003897734  46 TPVEADQGKVVLGGNElGp--VTAIGCETSDGLTTITI-----EsDVRTTVKVT-E----G-EAPNVESVNIGDVwSdGP 112 Mycolicibacterium
AIY48757      16 SPAKTGQGRVTFGPNDaGp--VTSVDCESKDGLTTIGI-----KgKMPASVVLT-D----G-AAPEVQSVNIGDVnGeGA 82 

4XIN_A        78 SGMYSRGGsg------sADMSMTGDKFTISGTAdgyKTDKP-GEPATATFKIVVTC 126 Mycobacterium avium 104
2_pfamImport  67 TGSFWAGTvg------kGRAGVANGKFRISGTAvgsFADNP-TDTVDAEFSIEARC 115
EID13406      92 TG-LADAGvg------kAKATFANGTYRITGTAegtNTEDP-STPKTADFNIETQC 139
WP_047314137  90 TGSFWAGGvg------dARAEVANNTYTITGSAsgiSSSDP-NKVVTAEFKITAEC 138 Mycobacterium haemophilum
O07750        92 NGSFWHGGvg------nARADRARNTYTVAGSAygiSSKKP-NTVVSTDFNILAEC 140 Mycobacterium tuberculosis H37Rv
EID11904      83 TGSFWRGGvg------dAVAHLARNNLTITGSAdgiDSARP-NKVTTTDFTVTVDC 131
WP_038549894 143 EGKEWESTdaq---erdATVEIDGDTYRVNGQLe-vDDDHPdAG-DVADLELEVSC 193 Corynebacterium glyciniphilum
WP_019512813 119 ALAYAFGVpvpatagraPTVLRNDATWIVTGSGsgtDSADP-ARIVDSSYRIAVAC 173 Mycobacteriaceae
WP_003897734 113 SVVYMSGLse-----vpVVATRDGDTYTVAGIGmgaDPADP-SVPADTPFDIAVTC 162 Mycolicibacterium
AIY48757      83 SLTYLAGLss-----vpVVAARDGKGYTITGTGmgiDPNEP-GTPVDMPFDIAVTC 132
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