Conserved Protein Domain Family
Kre9_KNH1_C

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pfam05390: Kre9_KNH1_C 
Yeast cell wall synthesis protein KRE9/KNH1 C-terminal
This is the C-terminal domain found in KRE9 and KNH1 proteins which are involved in encoding cell surface O glycoproteins, required for beta -1,6-glucan synthesis in yeast. In Saccharomyces cerevisiae, a kre9 null mutation leads to severe growth defects, aberrant multi-budded morphology, and mating defects. Over-expression of Knh1 suppresses growth defects of a kre9 null mutant. Knh1 is required for propionic acid resistance.
Statistics
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PSSM-Id: 398842
Aligned: 34 rows
Threshold Bit Score: 142.075
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002554398   179 SSLSTVPYTQQTYRTRFAPMQMQPGSTITATTWTRRFPTSAVTYYSTLRNwkSLEQLSTITPGWSYTISSDFNYATPMPF 258
CCE79879       155 SSLHSVPYTKQTGVVRYAPMQSQPGSKVTHSTWSRRFPTSSVSYYSTYRS--RPNVLTTTTIPWTYSRTSAANWASTAAF 232
EDK44494       164 SKSFTVPYTLQTGKTRFAPMQMQPGSTVTATTWTRRFPTSAVTYYTTKSK--SPVVMSTITPGWSYTMSSDVNWASVAPY 241
XP_001486016   170 SKSFSITYTLQTGKTRYAPMQMQPGSTITHSKYSTRYPTSAVTYYSTKAK--SPVVYSTITPGWSYSRKSYTNLATAQLF 247
EEQ37475       164 SASFTVPYTLQTGTWRFAPMQLQPGTTVTHTAYSTRHPSSAYTPFTSISP--SPNVYSTITPGWSYSVVSKINSAPVAPY 241
Q5ANN9         167 SKSFTVPYTLQTGKTRYAPMQMQPGTKVTATTWSMKFPTSAVTYYSTKAG--TPNVASTITPGWSYTAESAVNYASVAPY 244 Candida albicans
XP_007373106   166 SAWFTIPYTKQTGKTRYAPMQTQPGSKVTATTWTMRFPTSSVSYYTTKAK--SPVVYSTITPGWDYTAESAVNYATVAPY 243
ABN64556       172 SSLFTIPYTMQTSTKRFAPMQTQPGSKVTATTWSIKYPTSAVTYYTTKGP--KPVVMSTITPGWDYTPTSLPNAASVAPY 249
XP_013934134   158 SAWFTIPYTKQTGKTRYAPMQTQPGSTVTATTWSRRFPASSVTYYSTISG--TPVVHSTITAGWSYTMSSLTNYATPAPF 235
ybcl:Ecym_2770 163 lpssAVNYVSQTGRIFVAPMQLQPGSTVTAKTWTRRFPTSQVSYYTTKGP--VPSRVSTITPGWSYTIESGVNAETPALM 240
XP_002554398   259 PSQNGGWYNPKSRQSLSTRIRNL 281
CCE79879       233 PTE---FYPASSRVTKASLSTAA 252
EDK44494       242 PTY---WYPASQRVSTASITATK 261
XP_001486016   248 ETS---HYAASDKVKQATLSAGD 267
EEQ37475       242 PTY---YYPASSRVSQASLSSAR 261
Q5ANN9         245 PTY---WYPASERVSKATISAAT 264 Candida albicans
XP_007373106   244 PTN---WYPASERVSKATLSSAT 263
ABN64556       250 PSY---FYPASDRVSKATLSAAT 269
XP_013934134   236 PSEVG-WYAPSKRLQSATLDSSy 257
ybcl:Ecym_2770 241 PKDNGGWYEPARRVSLKPQKVNV 263
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