1QDP,2ROO


Conserved Protein Domain Family
Atracotoxin
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pfam05353: Atracotoxin 
Delta Atracotoxin
Delta atracotoxin produces potentially fatal neurotoxic symptoms in primates by slowing he inactivation of voltage-gated sodium channels. The structure of atracotoxin comprises a core beta region containing a triple-stranded a thumb-like extension protruding from the beta region and a C-terminal helix. The beta region contains a cystine knot motif, a feature seen in other neurotoxic polypeptides.
Links
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Statistics
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PSSM-Id: 398821
Aligned: 7 rows
Threshold Bit Score: 47.5619
Threshold Setting Gi: 226438097
Created: 11-May-2020
Updated: 6-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1QDP_A   1 CAKKRNWCGKNEDCCCPMKCIYAWYNQQGSCQTTITGLFK-KC 42 
P81885   1 CSRSDGWCGKTEDCCCPMKCIKAWYKQNGNCQNTISAIWK-NC 42  Hadronyche versuta
Q75WG5  27 CARKRAWCEKTENCCCPMKCIYAWYNGQSSCDHTISTIWT-SC 68  Macrothele gigas
P0C1R3   1 CAKKRNWCGKNEDCCCPMKCIYAWYNQQGSCQSTITGLFK-KC 42  Hadronyche sp. 20
P83608   1 CAKKREWCAKTEDCCCPMKCIYAWYNEQSSCQTTFSGMFK-KC 42  eastern mouse spider
P83560  63 CGSKRAWCKEKKDCCCGYNCVYAWYNQQSSCERKWKYLFTgEC 105 Macrothele gigas
2ROO_A   1 CGSKRAWCKEKKDCCCGYNCVYAWYNQQSSCERKWKYLFTgec 43
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