8A3V


Conserved Protein Domain Family
DciA

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pfam05258: DciA (This model is not part of the current CDD release)
Dna[CI] antecedent, DciA
This family contains several actinomycete proteins. Family members such as DciA (dna[CI] antecedent) found in Pseudomonas aeruginosa, has been shown to share a common function with DnaC (in Escherichia coli) and DnaI (in Bacillus subtilis), acting as a replicative helicase. Furthermore, functional analysis revealed that DciA is essential for replication initiation and protein depletion resulted in a blockage of the initiation of replication after the formation of the open complex.
Statistics
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PSSM-Id: 516732
Aligned: 79 rows
Threshold Bit Score: 51.1392
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
8A3V_C         16 DELIQAS-K--LK--QIQEh-AKAILLINRQLQDILPKGLKTQVRAANV-RGGNLVLEAASAALKMKVDYERLHILTQLR 88  Vibrio cholerae
Q9CLK5         10 IELLE------NSslAKIMkkGLFLNALNLHLQQRIPQQYQGLYNVANLeQDT-LYLDVANASVRQALLFEQKTILARIH 82  Pasteurella mu...
Q8PCJ4         22 EALLGEK----AG--DPLRr-ALWLDALDRQLRPLLPPHLATRCRLANV-RGEQLVFLVDSPVWHAKVRLAETQLLDAAR 93  Xanthomonas ca...
Q0A6V8         11 NHWLNNL-PveQRtlRQ-Lg---hFARLARRLNAEMPPELHGPWKLAAL-DAERLLLVTEDSLWATRLRYLETPLLDAAE 84  Alkalilimnicol...
jgi:Hhal_2028  32 HRIAPRL-AqrPGplRAVIdhARGLERLSRRLQRNLPAETRGHWRLARL-DEEEMVVIADGSGWGTRLRYLSRQLQDAAE 109
Q3SMG2          7 AELLA------TQlpNSLAtrARALLRTQDALDRALPSALSGHVRVMQL-ENGTLSVACESGAVATRLRQQTPAVLAALG 79  Thiobacillus d...
Q2Y645          7 DFYLGTLrL--TPehQRLFnhVEKLTEMQRAFKKIMPLNLGKHCALGGF-SEGSLTICADNGAIAAKLRHMLPSLLLKLQ 83  Nitrosospira m...
Q1GZ34          5 SALFTE-----NAelAALSqqAEQLALTQKKWNAVVPAALKPYTQAGSL-SHKRLTVYAANGAVAAKIKLMLPSLMLGLK 78  Methylobacillu...
Q5ZSB7          5 SQCLNKQ-L------STICqhSMQLEELSLKISAFLPSHFISKCQVGSF-NKGCLVLTTTNAAFASEIRYLLPELRDKLR 76  Legionella pne...
Q5R0M6          9 SEWLRSGqKtlSStlRHYAqfAAQLSHWQQLFQQCVDKNTSQHCQLLNI-RDGQMIIQVDNGSWATRLKLQQAAIITHFR 87  Idiomarina loi...
8A3V_C         89 QNGFGHLISiEVRV 102 Vibrio cholerae
Q9CLK5         83 QDY--PEVK-KIKF 93  Pasteurella multocida
Q8PCJ4         94 SIG--LKVT-AVtv 104 Xanthomonas campestris pv. campestris
Q0A6V8         85 RIGG-LRPR-RLEV 96  Alkalilimnicola ehrlichii MLHE-1
jgi:Hhal_2028 110 AISG-QRPR-RVTV 121
Q3SMG2         80 KHG----VD-ACAI 88  Thiobacillus denitrificans ATCC 25259
Q2Y645         84 AAG--YEVT-AIRI 94  Nitrosospira multiformis ATCC 25196
Q1GZ34         79 KQG--LEIT-SIRV 89  Methylobacillus flagellatus KT
Q5ZSB7         77 KEAGLYQLS-SIKI 89  Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Q5R0M6         88 HNAT-VPVQ-SLSI 99  Idiomarina loihiensis
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