Conserved Protein Domain Family
MinC_N
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pfam05209: MinC_N 
Septum formation inhibitor MinC, N-terminal domain
In Escherichia coli FtsZ assembles into a Z ring at midcell while assembly at polar sites is prevented by the min system. MinC a component of this system, is an inhibitor of FtsZ assembly that is positioned within the cell by interaction with MinDE. MinC is an oligomer, probably a dimer. The C terminal half of MinC is the most conserved and interacts with MinD. The N terminal half is thought to interact with FtsZ.
Links
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Statistics
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PSSM-Id: 487625
Aligned: 149 rows
Threshold Bit Score: 35.6269
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_050454925   9 FELRSGSVDT--LLFVVKTPD---LDALRTELTRRFEA-----TPEFFA-GDVVAIDV---RrlaedadGGEGERIA--L 72  Candidatus Burk...
WP_108674036  12 IDFKGITLYA--IKLVIYSND---INLININLRQHISK-----NPLFFQ-NESLILDL---Tn-----vN---DDID--V 67  Candidatus Kine...
WP_014111944   8 LEFKNVNLLT--LRLILRSTD---F----LSIEQNLNDflsgpNGQLLH-GENLVVDA---Fa-----lF---QPIS--W 64  Taylorella asin...
WP_015238332   6 IEFKSASFNVyaPKIIIHTSN---INDLSTSITKHIYN-----SGNFFK-NEHVVIDA---Tq-----iD---QIID--W 63  Candidatus Kine...
WP_159934017   6 IECKGSNFTL--LVFYLYNSQ---PEIIRKALQDKINQ-----APVFLQ-NAPIVLNV---Sa-----lN---NNTN--W 61  Pantoea sp. Aalb
Q1LT29         6 IDFKGSNFTL--LVIHIYDAP---IEVIIQAIQDKITQ-----APQLLK-NAPVILNV---As-----lSPECNWIN--- 63  Baumannia cicad...
Q057M2         6 ITFKNNNFTA--LVIYLENIN---FKYFKKFLLKKIQK-----SPIFFK-NIPIALNI---Ek----------lAFNfnW 61  Buchnera aphidi...
WP_075472631   6 IVMKGKNFTI--TVIYLKNIS---LNCLKKKLLKIIKK-----SPKFFQyA-PIILNIsklS-------------YSinW 61  Buchnera aphidi...
WP_080872406   1 MQIKVRNFSF--FVIYVYEKD---VNKLQKKIFHFLEK-----NPIFLK-NIPIIVNFkntKknfp-------------k 56  bacterium endos...
WP_046288902   7 IHLQISNFNL----PVIHIINatsHNDIENTIKKNMQE-----TRDFLK-YTPVVINV---An-----lT---HKNN--W 63  Blochmannia end...

WP_050454925  73 AELEKLLTsvrMRP 86  Candidatus Burkholderia verschuerenii
WP_108674036  68 KELLNVLKqhkLNI 81  Candidatus Kinetoplastibacterium sorsogonicusi
WP_014111944  65 SKLVNLLArykISV 78  Taylorella asinigenitalis
WP_015238332  64 DMLITILKeheINI 77  Candidatus Kinetoplastibacterium crithidii
WP_159934017  62 EKMKHAINktgLRI 75  Pantoea sp. Aalb
Q1LT29        64 --LLKAILstgLHV 75  Baumannia cicadellinicola str. Hc (Homalodisca coagulata)
Q057M2        62 INLKKFFFsigLFL 75  Buchnera aphidicola BCc
WP_075472631  62 KEIKNMMFsigFLV 75  Buchnera aphidicola
WP_080872406  57 klFLKIITkmgLNV 70  bacterium endosymbiont of Pedicinus badii
WP_046288902  64 EKLYQSILetkLYV 77  Blochmannia endosymbiont of Polyrhachis (Hedomyrma) turneri
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