5WZE,6H2P,3IG4


Conserved Protein Domain Family
AMP_N
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pfam05195: AMP_N (This model is not part of the current CDD release)
Aminopeptidase P, N-terminal domain
This domain is structurally very similar to the creatinase N-terminal domain (pfam01321). However, little or no sequence similarity exists between the two families.
Links
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Statistics
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PSSM-Id: 516689
Aligned: 398 rows
Threshold Bit Score: 75.232
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5WZE_A          9 YARRRKALMAQMEpNSIAILPAAPMYIRNR-DVEH-VYRQDSDFQYLTGF-P---EPEAVMALI----PGRA-Hge---- 73  Pseudomonas ae...
WP_010080559   76 AARRRAAVSARFP-GERIVVPAGRLKVRSN-DTDY-RFRAHSAFAHLTGL-GvdhEPDAVLVLEptdpGAGD-Dgtd--- 147 Micrococcus lu...
WP_012877549   57 TAARRARLAAQLP-GARLVIPAGPLKVRSN-DTDY-RFRPHSAFAHLTGL-GtdqEPDAVLVLHpvepGTGD-Lgpdgr- 130 Xylanimonas ce...
WP_012084497   86 AARRREVLSSLFP-HEVLVVPAGTLVRRSN-DTDY-RFRPHSAFAHLTGL-GtdrEADAVLVLHpragAEGhe------- 154 Kineococcus ra...
WP_015803430   49 AAEHRDRISAALP-GRTVVVAAGRAPNRNG-DADY-AFRAGSDFVWATSC-Qv---EGGVLVMTpr-tGGhd-------- 112 Actinosynnema ...
jgi:Acel_0669  76 AARRRRALQHALP-GRTIVVPAGAPKTRNN-DVAY-PFRASSDFWWLVGA-Nl---PDAVLVLD-----Dtd-------- 135
Q2GC22         46 YRERRARLMSVLk-DGVAVIHGAPRDQTGG-PVSP-PFHQSGDFAWLTGIaD---EPGAVLVLA-----PDE-Rtf---- 109 Novosphingobiu...
XP_001316865    7 FTERRNKLLDLIPeKVATIIVSGREPLYKSpGIPF-EYFQFSDMIYLTGY-E---NVSGTLLMT-----KDGnKyk---- 72 
WP_013567455   27 YRERRVKLSASLn-GGAAVLFAATEP-----LLDFmPYRQDSDFYYLTGW-T---EPGAALVIVge-gPETVlPrigtkv 95  Terriglobus sa...
WP_013837996   66 TAERRARLSARFP-GTRLVIPAGPLKTRSN-DTDY-RFRPHSAFAHLTGL-GtdhEPDAVLVLHpvadGEGD-Pgadgtp 140 Isoptericola v...

5WZE_A         74 ------yVLFCR------------ERDP----ERELWDGLRAGQD--GAIGQ-YGADdAFPIGDIDDILPGLIEg-rD-R 126 Pseudomonas ae...
WP_010080559  148 ----htaTLYFRplagrd-teqfyADSR----SGEFWIGPRPTLA--GLAAR-TGLR-TAGLEELESAITKNVAa--DgT 212 Micrococcus lu...
WP_012877549  131 --gdhhaVLYVRplaard-seefyADSR----YGEFWVGARPSLD--DVTTL-TGIE-ARHIDELRDALAKDVGa---gV 196 Xylanimonas ce...
WP_012084497  155 ------aVLYVRpqagre-teeffADAR----YGELWVGVRPTLR--EFEAQ-TGIT-CHDVAALADEVAASMAe--GtT 217 Kineococcus ra...
WP_015803430  113 ------aVLYLPpparpg-erdfyASAA----HGELWVGPSAGIA--AWERA-LGLP-VRPIADYDGTAAED-----AeR 172 Actinosynnema ...
jgi:Acel_0669 136 ------aVLYARapksrhdsdeffRDRQ----YGELWTGPQPSLR--DLERQ-LDIA-TAPLEECIERLQRS-----EeS 196
Q2GC22        110 -----reFLLLP------------SRDI----ETERWDVERLPLG--SLIEArTGMQrVRRTGSLDALVTQIAArsrT-- 164 Novosphingobiu...
XP_001316865   73 ------sTLFLP------------TKDKffdpNv----fGKISFD--ETLKT-SGVDeVLPMKSIGSHIVDAIGksrQ-- 125
WP_013567455   96 pahfyreILFLP------------ERNF----VMEKYTGAKLDASatDAATK-AGVDaVMPMRDLPGVLAQFAEadrRrL 158 Terriglobus sa...
WP_013837996  141 --shhhaVLYVRplaprd-neefyADAR----YGEFWVGARPTLE--DVTTL-TGIE-ARHVDELRDALAKDVGa--DgV 207 Isoptericola v...

5WZE_A        127 --VY 128 Pseudomonas aeruginosa PAO1
WP_010080559  213 avRL 216 Micrococcus luteus
WP_012877549  197 vlLV 200 Xylanimonas cellulosilytica
WP_012084497  218 tgLR 221 Kineococcus radiotolerans
WP_015803430  173 qrVV 176 Actinosynnema mirum
jgi:Acel_0669 197 rtVV 200
Q2GC22        165 --LH 166 Novosphingobium aromaticivorans DSM 12444
XP_001316865  126 --VY 127
WP_013567455  159 rtLW 162 Terriglobus saanensis
WP_013837996  208 riVV 211 Isoptericola variabilis
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