2GMJ


Conserved Protein Domain Family
Fer4_ETF_QO
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pfam05187: Fer4_ETF_QO (This model is not part of the current CDD release)
Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S
Electron-transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO) in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The two redox centres in the protein, FAD and a [4Fe4S] cluster, are present in a 64-kDa monomer.
Links
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Statistics
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PSSM-Id: 516682
Aligned: 38 rows
Threshold Bit Score: 192.827
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2GMJ_A       479 GQISFDLLSSVALSGTNHEHDQPAHLTLK--DDS-VPVNRNLSIYDGPEQRFCPAGVYEFVP----LEq--GdGFRLQIN 549 pig
Q83CJ5       438 GKLTFDKLTQVYLTGTQHRENEPCHLWVK--NQK-VETDITIPVYAAPEQRYCPANVYEIIE----KN---G-KPCLHIN 506 Coxiella burnetii
O22854       529 GVLSFDVPTSLYRSNTNHDHDQPSHLRLR--DPK-IPEKVNFPEYAAPESRYCPARVYEYIE----DEe--G-KPKLQIN 598 thale cress
Q54XM6       502 GQITFDLMTSVMRSGTNHEENQPIHLKVR--DME-VAKKVNRDIYDGPEGRFCPAGVYEWVE----GEk--G-EKELVRN 571 Dictyostelium d...
XP_011387149 549 GKLSFDILTSVSRTGTNHAEDQPVHLVVKegDYK-GHVERNVGTFEGPLGRCCPAGVYEYVEadtpDQedaL-GKKLVIN 626
P87111       527 NVLSFDIPTSVSRSATMHAENQPCHLF----DHRpKDRKSCFETYKGVENKFCPAGVYEYVN----DEassY-GKRFVIN 597 Schizosaccharom...
Q2GST5       534 GKLTFDILTSVSRTGTNHEEDQPVHLQVK--DWD-KHTAETWPAFKGVENRFCPAGVYEYVE----DAskpE-GVRFQIN 605 Chaetomium glob...
Q6FT04       549 GKLSFDIMTSVSRTGTYHDEDERSHLRVPnqDLT-AYATKSYPKFKGVEERFCPAGVYEFIE----DPsspI-GVKFKIN 622 [Candida] glabrata
Q08822       523 GVISFDILTSVSRTGTYHDDDEPCHLRVPgqDMV-KYAERSFPVWKGVESRFCPAGVYEFVK----DEkspV-GTRLQIN 596 Saccharomyces c...
Q6CTG0       553 GKITFDILTSVSRTGTYHDDDEKCHLRVPeqDME-KHTSIAYPKWKGIESRFCPAGVYEYVE----DEtspL-GVKFQIN 626 Kluyveromyces l...

2GMJ_A       550 AQNCVHCKTCDIKDPSQNINWVVPEGGGGPAYN 582 pig
Q83CJ5       507 ASNCIHCKTCDIKDPSQNIRWVVPEGGDGPNYS 539 Coxiella burnetii
O22854       599 AQNCLHCKACDIKDPKQNIEWTVPEGGGGPAYS 631 thale cress
Q54XM6       572 SVFCLHCKTCDIKDPTQNIDFTVPEGGGGPKYG 604 Dictyostelium discoideum
XP_011387149 627 SQNCIHCYTCSIKTPDQSIRWDVPEGGGGPKYS 659
P87111       598 SQNCVHCKTCDIKDPLQGIQWKTPQGGDGPKYT 630 Schizosaccharomyces pombe 972h-
Q2GST5       606 AQNCIHCKTCDIKAPNQDINWQVPQGGEGPKYY 638 Chaetomium globosum CBS 148.51
Q6FT04       623 SQNCIHCKTCDIKSPIEEIKWVVPEGGDGPKYT 655 [Candida] glabrata
Q08822       597 SQNCIHCKTCDIKAPRQDITWKVPEGGDGPKYT 629 Saccharomyces cerevisiae S288C
Q6CTG0       627 SQNCIHCKTCDIKVPTQDINWEVPEGGDGPKYT 659 Kluyveromyces lactis
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