2J7N


Conserved Protein Domain Family
RdRP

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pfam05183: RdRP 
RNA dependent RNA polymerase
This family of proteins are eukaryotic RNA dependent RNA polymerases. These proteins are involved in post transcriptional gene silencing where they are thought to amplify dsRNA templates.
Statistics
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PSSM-Id: 398723
Aligned: 264 rows
Threshold Bit Score: 282.145
Threshold Setting Gi: 170090286
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2J7N_A        135 LKPLMFEQ-GCRLTRRFgpDRFFEILIPSptstspsvppvvskqpaaveeviQWLTMGQHSLVGRQWRAFFAKDAGYRKp 213 
EES00122      354 FKGPYVENtRTHLQKIVgdDNVLIVKFADipdlenntd-----nlgiycqyySQVADDGIVLGLRRYRFFIHKDGGKTEk 428  sorghum
CBI28010      189 FKGPYLNKtRTHLQRVLgdENILLVKFAEdvtdrssln-----cstdsnasyNKIAREGIFVGLRQYRFFVFKDGGKEEk 263  wine grape
KRH74267      211 FKGPILQStRTHLQKTLgdDNVLLVKFAEdgsgknfrt-----haeeanalyGKFGKEGIRVGLRLYRFFVFKDGGNEEk 285  soybean
O82189        228 LKGYFLENtGTHLHKVLgdDNVLTVRFDQlpkestyc--------dnpyskyKEIAKNGIMVGLRRYQFFVFKDGGKAEk 299  thale cress
O82190        228 FKGHLLENtGTHLHKVLgdDNVLTVKFDKvlgvetyc--------ndlystyKGIAKNGIMVGLRRYRFFVFKDGGKEEk 299  thale cress
O82188        223 LQGPLLEHtGTHLHKVLgdDNVLTVKFADvqksssty-------sidhyftyKGIAKNGIMIGLRRYQFFVFKDGGKEEk 295  thale cress
XP_009117512  248 FKGPLMENtGTHLHNVLgdENVLTVKFADvpgeatyc--------ndiystyKEIAKKGIMLGLRRYQFFVFKDGGKEEk 319  field mustard
VAI90085      409 FKGPYIENtRTSLQKVVgdDNVLVVNFSDisghtnagd-----nfetgchfyHHVFEDGIILGLRRYRFLIYKDGGRERr 483  durum wheat
XP_015697449  207 FKGPYVENtRTHLQKVIgdDNVLVVNFMEkpsdiktd-------fltycahyHKVAEDGIVLGLRHYRFFLYKDGGKDSk 279  malo sina
2J7N_A        214 lrefqlraedpkpiikERVHFFaetgitfrpdvfktrsvvpaeepveqrtefKVSQMLDWLLQLdNnTw-QPHLKLFSRI 292 
EES00122      429 lkeekkkeknkklspsVRCYFVrmesgwerd-------------ypykladyTVNQARRLFMHI-N-Na-PTVAKYLSRF 492  sorghum
CBI28010      264 kkn---------ptssVKCYFVfmess--------------------alsgkTVHEARCIFMHA-H-Mv-SSVAKYMARF 311  wine grape
KRH74267      286 qkdp--------tsstVKCYFVrmqsgcsade-----------gadyilsnkTVSEARTLFMHA-H-MllPNLNKYMARF 344  soybean
O82189        300 kkrn--------stkqVKCYFIrtgstassdm-----------enpyilsgmSIHEARMHFMHV-H-Tl-PSPANYMARF 357  thale cress
O82190        300 kkdv--------stkgVKCYFIrtdstasidm-----------qnpyifagkSMHEARMHFMHV-N-Tl-SSLPNYMSRF 357  thale cress
O82188        296 kkdl--------stkkVKCYFIrtdstafydm-----------qnpyiltgkSIYEARMHFMHV-H-Ra-PTLANYMARF 353  thale cress
XP_009117512  320 kkdf--------sgkgVKCYFIrtdstssndm-----------gkpyifsgkSIHEARMHFMHV-H-Tl-PTLAKYMARF 377  field mustard
VAI90085      484 ikaekkkernkkctstVRCYFVrtecdwdkg-------------vpyilskrTVGDARKLFMHV-H-Tv-PSVAKYVARF 547  durum wheat
XP_015697449  280 mkeekrkeknkkctssVRCYFVrtesrwnmd-------------epyilsgkTIGQARGLFMHI-H-Ta-LTLPKYMSRF 343  malo sina
2J7N_A        293 QLGLSKTYAimtlepHqi-------------------------rHHktdllspsgtgevMNDGVGRMSRSVAKRIR---- 343 
EES00122      493 ALILSKTIK------Ldvdfskvnvkiidd-epcreesgeiavqDGkd---------liHTDGTGLISVDLARNCPssif 556  sorghum
CBI28010      312 SLILSKTVK------LdvdlstvniqriddepgrdedghvvydeDWkp---------liLTDGTGFISEDLALRCPnnlc 376  wine grape
KRH74267      345 SLILSKTLK------Lnidlttvsvqkipd-eyckdangnimvdNEkp---------riLTDGTGFISRDLALLCPnnvy 408  soybean
O82189        358 SLILSKTKK------LevdmteitvmqiddihchdqsnndvldkNGkp---------riHSDGTGYISEDLARMCPlnif 422  thale cress
O82190        358 SLILSKTKT------LevdmtgitfeqiddihchdqddkdvldkNGkp---------ciHSDGTGYISEDLARMCPvnif 422  thale cress
O82188        354 SLILSKTKT------LevdmtgitfdqiddihchdqdgkdvldkNKkp---------ciHSDGTGYISEDLARMCPlnif 418  thale cress
XP_009117512  378 SLILSKTRK------LevdtsriafqqiddihchdqnnndvldkNQkp---------ciHSDGTGYISEDLARMCPtdif 442  field mustard
VAI90085      548 GLVLSKTITl----lDgealskidvvivdd-vpckdkngsivlkHRea---------liHTDGTGLISEDLAKKCPtdvf 613  durum wheat
XP_015697449  344 ALIVSKTIT------Ldvdlsavrvelidd-epcldehrnfvfrDGep---------liHTDGTGLISQDLALKCMssif 407  malo sina
2J7N_A        344 DVLGLg----------------------------D-V-------------------PSAVQGRF----GSAKGMWVIDvd 371 
EES00122      557 KGNFLkdavdsk----------------ghqhltTkH-------------------PLLIQFRMfhngYAVKGTLLADkr 601  sorghum
CBI28010      377 RGKYMnn--------------------------gNsD-------------------PLLIQCRLfnngCAVKGTLLLNrk 411  wine grape
KRH74267      409 KGSNLennciqeinnlveledmsnamgeaeqlstHeP-------------------PLLIQCRLfhmgHAIKGTLLVNrk 469  soybean
O82189        423 KGKSMrsnni-------------------qgtcvQeP-------------------PLLIQIRMfndgSAVKGIFLLNkn 464  thale cress
O82190        423 KGKSMrsnniqsknl----------nfegqgpcgQeP-------------------PLLIQFRIfyngYAVKGTFLTNkk 473  thale cress
O82188        419 KGKCLrsesi-------------------qeacyQdP-------------------PLLIQFRMfydgYAVKGTFLLNkk 460  thale cress
XP_009117512  443 KGKHVrsdnmq------------------antygKeP-------------------PMLIQFRMfhygYAVKGTFLLNkk 485  field mustard
VAI90085      614 KGNLLr----------------------------IhDdsvdsked----qfdiddhPLLMQVRMfyngLAVKGTLLVVrk 661  durum wheat
XP_015697449  408 KGKLLkpqvs-------------------kgkllKqQdivdcdesklmgynstteyPLLIQLRLfyngSAVKGTVLVDkr 468  malo sina
2J7N_A        372 ---dTgdedwIetYPSQRKWecDFv-------dKHqr-------------------tLEVRSVASELkSAGLNLQLLPVL 422 
EES00122      602 lpanT-----IhiRPSMIKI--HGdens--fgeKSfn-------------------sLEVITTSYRPkRAFTSRFLISLL 653  sorghum
CBI28010      412 lpprT-----IqiRPSMIKV--ETdpkl--sdtQTvn-------------------sVEINGTSNQPrRSYLSKYLIALL 463  wine grape
KRH74267      470 lpprT-----IqvRPSMIKV--EKdps---vhmQSin-------------------sLEVVTTSNKPkRGYLSKHLIALL 520  soybean
O82189        465 lppqT-----VqvRPSMIKV--YKdknl--snfSTfn-------------------sLEVVTTSNPPkRAKLSKNLVALL 516  thale cress
O82190        474 lpprT-----VqvRPSMIKV--YEdrtl--snlSTfn-------------------sLEVVTTSNPPrKARLSRNLVALL 525  thale cress
O82188        461 lcprT-----VqvRPSMIKV--SKdpsl--snfSTfn-------------------aLEVVTTSNPPkRTKLSKNLVALL 512  thale cress
XP_009117512  486 lpprT-----VqvRPSMVKV--SEdpal--ynfSTfn-------------------sLEVVTTSNPPrRTKLSRNLVALL 537  field mustard
VAI90085      662 lperT-----IhiRPSMIKV--NSdpsl--sggHSfn-------------------sLEIVSTSNRPkRALTSRFLITLL 713  durum wheat
XP_015697449  469 lspgT-----IliRPSMVKI--KTdpklssihsVNsfeivsarnakkslsdvqfvnsFEIVSTSNRPrRTSTSRILIALL 541  malo sina
2J7N_A        423 EDRArdkvKMRQAIGDRLINDLQRQFSEQKHAlnrpvefrqwvyesyssratrvshgrvpflaglPDSQEETLNFLMN-S 501 
EES00122      654 HYGR----VREEFFLDLLRNALEDVNNARHRPrnsle------------------------vafnHADLDDSMSARMIlS 705  sorghum
CBI28010      464 SYGG----VPNEYFMNLLKDALEDAPSVQSSKraalr------------------------vslrFGEMDDSIVTRMIlS 515  wine grape
KRH74267      521 SFGG----VPNEFFMDLLRSNMEDANHVYSNKrsalr------------------------asinCGEKDEYNAAEMIlC 572  soybean
O82189        517 SYGG----VPNDFFLDILLNTLEKKKTIFFKVraagk------------------------aalhYGNMDDKNALQMImA 568  thale cress
O82190        526 SYGG----VPNDFFLNILRNTLEESKTIFYSEraafk------------------------aainYG--DDQYTADMIlV 575  thale cress
O82188        513 SYGG----IPNEFFLDILLNTLEESKSIFYNKraaln------------------------aalnYGEMDDQNAAQMIlV 564  thale cress
XP_009117512  538 SYGG----VPDEFFLDILRSTLEESKTVFDNKraavr------------------------aarnYGDMDEYNALQMImS 589  field mustard
VAI90085      714 QYGG----VPADYFMELLGKALKDVEKARHKTrdsle------------------------vafnHGDMDDLMSARMIlS 765  durum wheat
XP_015697449  542 HYGG----VPEEFFMELLQNAIEDAENARFDYgdaln------------------------iafsYADMEDSMSARMIlA 593  malo sina
2J7N_A        502 GFDPKkqKYLQDIAWDLQKRKcDTLKSKLNIRVGRSAYIYMIADFWGVLEENEVHVGFsSkfrdeeesftllSDCdVLVA 581 
EES00122      706 GIQPEdeAYLQSQLALMAKVE-RKGLKEGRIPIDDTYYLMGTTDPTGTLKRDQVCIILdNg----------qLSGkVLVY 774  sorghum
CBI28010      516 GI-PIdePFLHHCLSFMVNEE-RKGLRVGKLPVNDCFYLMGTADPTGTLKSDEVCIILdHg----------qVQGrVLVY 583  wine grape
KRH74267      573 GI-PLdePFLKHHLSRFAREE-KKKLRGGKLYMPDCFYLMGTVDPTGHLKKNQVCIIHeNs----------qIVGdVLVY 640  soybean
O82189        569 GI-PLdePYLKHYLSKLLKLE-KDDLKAGKLPIDESYYLMGTVDPTGELKEDEVSGLA--------------KSQdVLVY 632  thale cress
O82190        576 GI-PLdePYLKDRLSYLLKTE-RNALKAGRFPIDESYYIMGTVDPTGELKENEICVILhSg----------qISGdVLVY 643  thale cress
O82188        565 GI-PLdePHLKNYLSILLKTE-KNDLKAGKLPVTESYYLMGTVDPTGALKEDEVCVILeSg----------qISGeVLVY 632  thale cress
XP_009117512  590 GI-PLdePHLKDHLSILLNTE-KNDLKAGKLLVTESYYLMGTVDPTGKLKQNEVCVILeSg----------qISGdVLVY 657  field mustard
VAI90085      766 GIRPEdeAYLQHQLTTMTKEE-REGFKQGRLPVDQCYYLMGTTDPTGTLKPHEVCVILdHg----------pISGeVLVY 834  durum wheat
XP_015697449  594 GI-PLdeLYLQSRLTFMAKQE-RKGIKEGKIPIDNCYYLMGTADPTGILAPNEVCVILdNg----------qLSGdVLVY 661  malo sina
2J7N_A        582 RSPAHFPSDIQRVRAvfK-PELH----SLKDVIIFSTKGDVPLAKKLSGGDYDGDMAWVCWDPE-IvdgF---Vn---aE 649 
EES00122      775 KHPGLHFGDIHILTAt-YiDGLEkivgNSKYAIFFPTCGPRSLADEMANSDFDGDLYWVSRNPQlLe-gFtkqRkp--wV 850  sorghum
CBI28010      584 KHPGLHFGDIHVLNAt-YvEALEefvgNAKYAIFFPIKGPRSLADEMANSDFDGDMYWVSRNQQlLq-yFr-aSep--wM 658  wine grape
KRH74267      641 RNPGLHFGDIHKMDAt-YvKELEsyvgHSKYGIFFPRVGTRSVADEIAGGDFDGDTYWVSNHPQlLq-yFr-kGdp--wI 715  soybean
O82189        633 RNPGLHFGDIHILKAt-YvKSLEqyvgNSKYGVFFPQKGPRSLGDEIAGGDFDGDMYFISRNPKlLe-hYk-pSep--wV 707  thale cress
O82190        644 RNPGLHFGDIHVLKAt-YvKALEdyvgNAKFAVFFPQKGPRSLGDEIAGGDFDGDMYFISRNPKlLe-hFk-pSep--wV 718  thale cress
O82188        633 RNPGLHFGDIHILKAt-YvKALEeyvgNSKFAVFFPQKGPRSLGDEIAGGDFDGDMYFISRNPElLe-nFk-pSep--wV 707  thale cress
XP_009117512  658 RNPGLHFGDIHVLKAt-YvKALEeyvgNSKYGVFFPQKGPRSLGDEIAGGDFDGDMYFISRNPKlLe-hYk-pSep--wV 732  field mustard
VAI90085      835 RHPGLHFGDIHVLTAt-YsEAIQdfvgDSKYAILFPVSGPRSLADEMAGGDFDGDMYWVSRNPQlLk-yFk-pSep--wD 909  durum wheat
XP_015697449  662 KHPGLHFGDIHVLKAt-YiPGLEevvgCSKYVILFPTTGQRSLADEMANSDFDGDIFWISINPKlLe-hFk-pSkawewE 738  malo sina
2J7N_A        650 Mp---------LEP-DLSrylkkdkttfkqlmashgtgsaakeqttydmIQKSFHFalQPNFLGMCTNYKErLCYi---- 715 
EES00122      851 Rriqpt-ktelKKPqDYTgpkle---------------------sllfhEFLRARFt-PSYVLGAASNCWL-ALMdrllt 906  sorghum
CBI28010      659 Rkrstr-hvpsKRPtDFSpdele---------------------helfqLFLTTRFq-TSSAIGMAADNWL-VFMdrllt 714  wine grape
KRH74267      716 Ensvpl-dssvKKPsEFSpeele---------------------eelfrLFLKTRFq-PSYAMGMSENSWM-ALMdrllt 771  soybean
O82189        708 SssprskiytgRQPsELSpeqle---------------------eelfkIFLKTGFs-PSSVIGQAADSWL-AIMdrflt 764  thale cress
O82190        719 SsskpskiycgRKPsELSeeele---------------------eelfkMFLKARFc-KRDVIGMAADCWL-GIMdpflt 775  thale cress
O82188        708 SltppsksnsgRAPsQLSpeele---------------------eelfeMFLTAGFh-ASNVIGIAADSWL-TIMdrfli 764  thale cress
XP_009117512  733 SssppskiytgRKPsELSpemle---------------------eelfrLFLKARFh-SSNVIGAAADSWL-RIMdqflt 789  field mustard
VAI90085      910 Prnppr-kakqEKPqDYDeskle---------------------hilfrEFFRIRFt-PSYVLGAAADCWL-VYMdrllt 965  durum wheat
XP_015697449  739 Qaitpk-eakqMGPqDFNesele---------------------rllfhEFLKARFa-PSYALATASNNWL-VYMdrllt 794  malo sina
2J7N_A        716 -----------nNSVSNKPAIILSSLVGNLVDQSKQGIvfnEASwaqlrrELlGGAlslP--DPMYKsdSWlgrgeP--- 779 
EES00122      907 g-----gvpkseRQAIKKKMLDLVDIYYLALDAPKEGN---KIT------VPgELK---VkkYPHFMerDEk----Ksyt 965  sorghum
CBI28010      715 lr----ddcsdeKECLKRKMLELTDIYYDALDAPKSGM---KVN------VSkELK---AekFPHFMgrESsy------h 772  wine grape
KRH74267      772 ln---nctneneKERVKENMLKLIDIYYEALDAPKSGR---KVQ------VPnDLI---AelFPHYMekDKsf------t 830  soybean
O82189        765 lg----denvkeKAEMKKKMLKLTDIYYDAIDAPKTGT---EVN------LPlDVK---VdlFPHYMerNKtf------k 822  thale cress
O82190        776 lg----desakeKYERKKNILKLIDIYYDALDAPKKGA---KVD------LPpDLE---IknFPHYMerDPk----Rdfr 835  thale cress
O82188        765 lg----ddraeeKAEMKKKMLELIDIYYDALDAPKKGD---KVY------LPnKLK---PdiFPHYMerDKkf------q 822  thale cress
XP_009117512  790 lgddrvketaerKSKMVKTMLKAIDIYYDALDAPKNGA---KVD------LPlDLK---FdsFPHYMerKNk----Kifk 853  field mustard
VAI90085      966 ce---vqedkkeWESIKAKMLELVDIYYEALDAPKSGN---KIT------MPrHLR---VevYPHFMegKGf---tPpyt 1027 durum wheat
XP_015697449  795 d-----pvdeseKELIKEKMLKLVDLYYVALDAPKSGK---KVN------IPsDLM---VkqYPHFMgrSSsy------h 851  malo sina
2J7N_A        780 -THIIDYLKFSI 790 
EES00122      966 sTSVLGKIYDEV 977  sorghum
CBI28010      773 sTSILGQIYDAV 784  wine grape
KRH74267      831 sTSILGLIYDEV 842  soybean
O82189        823 sTSILGLIFDTV 834  thale cress
O82190        836 sTSILGLIFDTV 847  thale cress
O82188        823 sTSILGLIFDFV 834  thale cress
XP_009117512  854 sTSILGLIYDTV 865  field mustard
VAI90085     1028 sTSVLGKIYDLA 1039 durum wheat
XP_015697449  852 sSSILGKLYDKA 863  malo sina
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