4CR2


Conserved Protein Domain Family
DSS1_SEM1
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pfam05160: DSS1_SEM1 (This model is not part of the current CDD release)
DSS1/SEM1 family
This family contains the breast cancer tumour suppressor BRCA2-interacting protein DSS1 and its homologue SEM1, both of which are short acidic proteins. DSS1 has been shown to be a conserved component of the Rae1 mediated mRNA export pathway in Schizosaccharomyces pombe.
Links
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Statistics
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PSSM-Id: 516661
Aligned: 83 rows
Threshold Bit Score: 26.3663
Created: 14-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4CR2_Y         28 SLEEDDEFEDFPID-TWANGETiksNAVT-QTNIWEENWDDVEVDDDFTNELKAELDR 83  brewer's yeast
XP_067521748   24 VLEEDDEFEEFAAE-DWGEEEE---D--QnDAHFWEDNWDDDDIEDDFSKQLRAELEK 75 
XP_002511422   17 LFEDDDEFEEFDINqEW-EEKE---EGKE-MTQQWEDDWDDDDVSDDFSLQLRRELDN 69 
XP_034708254   16 LFEDDDEFEEFEINeEW-DDKE---EGKD-TTQQWEDDWDDDDVNDDFSLQLRKELEN 68 
XP_006858054   21 LFEDDDEFEEFENE-EWDDDKE---DGKE-GLQQWEDDWDDDDVNDDFSLQLRRELES 73 
10_pfamImport   8 LFEDDDEFEEFEINqDWVENEE---QVKE-VGLQWEDDWDDDDVSDDFSHQLRKELET 61 
XP_020890607   17 LFEDDDEFEEFEINeDW-LEKE---EVKE-VSQQWEDDWDDDDVNDDFSRQLRKELEN 69 
XP_020890906   16 LFEDDDEFEEFEINeDS-LEKE---EVKE-VSQQWEDDWDDDDVNDDFSRQLRKELEN 68 
XP_002283106   16 LFEDDDEFEINE---EWEDRAE---EKV---AEQWEDDWDDDDVHDDFSQQLRKELEN 64 
XP_025177148   42 ALEEDDEFEEFIAE-DWNETEE---D--Q-ETHLWEDNWDDEDVEDDFSKQLRAEITK 92
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