Conserved Protein Domain Family
Phage_prot_Gp6

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pfam05133: Phage_prot_Gp6 
Phage portal protein, SPP1 Gp6-like
This bacteriophage protein forms a gateway that enables DNA passage during packaging and ejection of the phage genome. It also forms the junction between the phage head (capsid) and the tail proteins. During SPP1 morphogenesis, the portal protein, Gp6, participates in the procapsid assembly reaction. In the mature SPP1 virion, Gp6 exists as a dodecamer, while recombinant SPP1 Gp6 has been shown to form 13-subunit assemblies. This protein is common to Siphoviridae (phages with long non-contractile tails) and Myoviridae (phages with contractile tails). It is also found in a number of bacterial species. This family also includes the old Pfam family Phage_min_cap (PF:PF05126). RC Paper describing PDB structure 2jes
Statistics
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PSSM-Id: 398687
Aligned: 45 rows
Threshold Bit Score: 182.914
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
cebbi:LBUCD034_0946  65 YVSDHFNNQLPRILELERYYLAD--------NNIHYWLsNKRSNRADNRISSALARYITNIQVGYEFGTPLTFGYQNKDD 136
Q8Y4Y0               29 KKVNANDEDYKYIDMWKRLYQGHyaewhnlnYE------HNGNPVNRRQLSMNLPKVTAKYMSKLLFNEKVKINIDDKAA 102 Listeria...
Q9A0P3               30 PKIAISKLEYDRITTNLKYYKSDwdsv--------lylnTDGETKKRDLNHLPIARTAAKKIASLVFNEQAEIKVDDDAA 101 Streptoc...
SKLIDPC::KE3_1409    30 PKIAVSQEEYSRIQHNLTYYQSKfddv--------eyinSEGDVKRRKFNHLPIARTASKKIASLVYNEQAEITSDNKSV 101
BAK21848             32 PKIGIDTQEYIRINENMKYYANIypdv--------qyknSYGQDKRRSFNPLNLTKTAARRLASIIFNEKCEVVLDVAEE 103
WP_011904463         11 ELLAILERDLPTLRRVDDYLNGRhddpy------mparaDAEYRLLARRAITNMSLILVGTPAQALYVDNYRRGGTDRVA 84  Salinisp...
ABS03208             15 VLWPEWEQQRQHLDWIDRWarwvpde------iklprtaTAEHKRLAELSNTPWLSLVVTTTAQCLGVDSLKSSRDIGRD 88 
jgi:Srot_0064        23 RLFDELTRRAGRNQSRSRLYEGKyavk---------rtsTIPPEYFRMGIVLGWAAKAVDILARRCNLDGFTWADGDLES 93 
CBG73129             11 HLIQCHDREKPELTLLDSYYEGEqplsylapEL------QAEMDERIRQVVVNWPLLVADSLEERLDVEGFRFPDEAQAD 84 
CDA69854             37 NCIGAFYYNKTVIEYLWNYYKGD--------QPVLYRT-KVSNEDICNSIVENHSYEIVQFKVGQTYGEPIQFVSRKEDD 107
cebbi:LBUCD034_0946 137 Endtge---nviqAVDDFNQTNDEPYHEKIMGKNLANVGRAYELLYVPE---G---TKqpKITAIDPN--SAFVVWSTdv 205
Q8Y4Y0              103 Ee-----------FVLNVLKTNGFTKNMERYIEYGEAMGGFVIKVYHDGk--K---NV--KVSFATAD--CMYPLSNDse 162 Listeria...
Q9A0P3              102 Ne-----------FISETLKNDRFNKNFERYLESCLALGGLAMRPYVDG---D---KV--RVAFVQAP--VFLPLQSNtq 160 Streptoc...
SKLIDPC::KE3_1409   102 De-----------FISYTLDNDRFNKNFERYLESGLALGGLAMRPYVDG---D---RI--RVAFVQAP--VFLPLQSNtq 160
BAK21848            104 QsidketlakaneFLQSVLIDNNFFNLLELNLEKGIALGGFAMRPYIDAk--G---KI--KISWIRAD--QFYPLQSNtn 174
WP_011904463         85 Ddt--------vlPEWLHWQESRLDARQTAVHRAALAYGHSFVLTERQA---G---RV--RSKGLSPL--RTVAVYDDpa 146 Salinisp...
ABS03208             89 Ldpq-------erGPWRTWVMNRFDQRQNAIHRAALTYGTAYNKIMPGQd--QrsgEPmaVMRGVSPR--RMLALYRDpa 157
jgi:Srot_0064        94 L------------GSREVWSENLLGTESDSGVVSSLIHGPAFLVNTAGEaweP---KA--LIHVKDAL--NAVGDWNPra 154
CBG73129             85 E------------ELWRIWQANRLDSRSHQGHLDGLVMRRAYVIVGAREd--D---PKtpLITVESPL--DVYAEHDPrt 145
CDA69854            108 Atnk------avdTLNDYMENANKQEKDIKAGEWQSATGTSFKAAQFSN---G---DI--PFRIVAPTpmNTFVIYNRg- 172
cebbi:LBUCD034_0946 206 EPVELFAVRYYa---VNVADETYYQIEVYTDNHIYHFTAGANPDS------------DWKLTSDEGHYFQ-QVPLTEYRL 269
Q8Y4Y0              163 NVDECVIANSF-----------HKNDKYYTLLEWNEWQDDIYTVT------------TELYQSDDPDELGgKVSLKLLFN 219 Listeria...
Q9A0P3              161 DVSSAAVVIKS-------VKTINGKEVYYTLIEFHEWQSSDDyv-----------isNELYRSDDKAKVGsRVPLSEVYK 222 Streptoc...
SKLIDPC::KE3_1409   161 DVSNAAILTKA-------IKSEGRKNVYYTLVEFHEWVTADGNEQgstkdksyyritNELYKSDISDALGqRVNLPELYP 233
BAK21848            175 EISECAIATKK-------TITIGNKQYYYTLLEFHEWENNAyi------------ieNELYKSESPETVGkRVPLAEIYD 235
WP_011904463        147 NDDAPVAAITVtqwpKPGDKGSRGSARMWDGRREYTITFRSLTDAt-----------SVGITGKRVHGSS-ECPVTRFAS 214 Salinisp...
ABS03208            158 EDDWAEYTIEV----GSKGSDDLRLVEVMDDEAVYRVSLDASTG-------------KIEYIDDSRHEVG-VVPVVRYTN 219
jgi:Srot_0064       155 RRLENLLSITD-----RDEEDRVTGFALYMDGLTVSAARDS----------------SGWAVERSDHKFG--VP-AEPLV 210
CBG73129            146 GAVAAAVKRWCe---EEEGASPIEHATLYLPGATSWWTKDRSGVWaed-------tgDEGEPTRDDHGLG-EVPVVPLA- 213
CDA69854            173 TEEPILSVQEL------KDENGKSYKQCYTDTHECKIV-------------------NSQVVDWKLHAFG-GNPIVEFPN 226
cebbi:LBUCD034_0946 270 ------------------------NEERVG-------AWETKLDEIDAYDQALSEMANSQEDFSNAMLMINGkvanhsgk 318
Q8Y4Y0              220 diepvvplpkftrptfiyikpniaNNKNLTspl-gisVYANALDTLKTLDLMFDSFYQEFKLGKKKVLVPSSfvktaigl 298 Listeria...
Q9A0P3              223 dlkdeakvtdvtrpiftylktpgmNNKDINspl-glsIFDNAKTTIDFINTTYDEFMWEVKMGQRRVAVPESltaltvrt 301 Streptoc...
SKLIDPC::KE3_1409   234 dleqvtmfkdlsrplftylktpgmNNKDINspl-glsIFDNAKTTIDFINRTYDEFMWEVRMGQRRVIIPEQmtkvtaqr 312
BAK21848            236 dladtvkltglqrplftyfrtpgaNNKSLEspl-gmgIVDNSREILDQINLTHDQFSWEIQMGQRRVIVPAEwlrvnend 314
WP_011904463        215 ------------------------CVDLEGrt---lgVIEPMIALQNRINQTVFDLLVAQTYGSFTVRTATGmapplktr 267 Salinisp...
ABS03208            220 ------------------------MLDLDGrs---fgEVEPFIVVAARANKTLYDRLLVQHFSSWKIRTVAGma------ 266
jgi:Srot_0064       211 ------------------------YKPRAGrpfgssrINRAVIALLEQATRVAIRMEAHADTFSFPEFWMFG-------- 258
CBG73129            214 ------------------------NRARLKkpg-gvsELKAVIPLSDAACKIATDMMVSAEYHATPRRVAFG-------- 260
CDA69854            227 ------------------------NHERLS-------DIEIVISMLDAINNMQSNRMDGIEQFVQSWIKFVNc------- 268
cebbi:LBUCD034_0946 319 teqmldpkgqpVYLDNVSGgyt------nqSTTngkpnapvmvqkvldtk--anvlylkpymhdnpngSPTISNTSASYL 390
Q8Y4Y0              299 d--gsttqyfdSTDEAFFLyq----------------------------------------------gDQDADGKSVKDI 330 Listeria...
Q9A0P3              302 adgdvvprprfESDQNVYIrm----------------------------------------------gGRDLDSSAIQDL 335 Streptoc...
SKLIDPC::KE3_1409   313 edgsitfkrrfETDQNIYTql----------------------------------------------gGGNMDANSIKDI 346
BAK21848            315 ----parpmlfDTAQNVLMgm----------------------------------------------yGDSSQTIGIKDV 344
WP_011904463        268 pvhqrgqepytYPDEPAVAgvdslgravdrDGWvlddngqrvildtapvvdpvtgqhvyeqvdisarrFLFAKDPQSKWG 347 Salinisp...
ABS03208            267 ---------kpEDDEEAARaklql----------------------------------------rqddLLVADDPDTKFG 297
jgi:Srot_0064       259 -----------ATLADLAGgeknpnpwr--------------------------------vrmgrikgLPDDEETGVRAE 295
CBG73129            261 -----------FGEDDFQDeqgrkvsafsr---------------------------iigrvwaterrRGSGEDGGADVI 302
CDA69854            269 ----------dIDEEQFEK-----------MKMshal---------------------------vvksINKDNKSDVDVM 300
cebbi:LBUCD034_0946 391 TKSLNAAEWQIYIQQLLSDIHKDTNTPDTTDQNFa-----ANASGVAMAYKLWGSDQEMSMSETLYQRGLRRRLRLLAIY 465
Q8Y4Y0              331 SVEI---RSTEFIESINAMLRIYAMQVGLSAGTFtfd-enGLKTATEVVSEKSETYQTKNSHSQLIEQGIKEMIVSILEV 406 Listeria...
Q9A0P3              336 TTPI---RADDYIKAINEGLSLFEMQIGVSAGLFsfd-gkSMKTATEIVSENSDTYQMRNSIVTLVEQSLKELVISIFEI 411 Streptoc...
SKLIDPC::KE3_1409   347 TTPI---RSNDYITAISEGLKLFEMQIGVSAGMFsfd-gkSMKTATEVVSENSDTYQMRNSIAALVEQSIKELCVSICEL 422
BAK21848            345 TTAI---RTVQYKDAIDHWIKEFEVQIGMSTGSMsya-ddGLKTATEVVSDNSMTYQTRSSYLTMLEKALDELIHAIFEL 420
WP_011904463        348 SL--DATPLGGFIDSLDMSFRQFSALAQVPPHHLlg--qiANLSAEALQAAETALARKVEEFRKLFGESWERVFRLAAEL 423 Salinisp...
ABS03208            298 TL--DETPLGGFLDAERQDRETLSAVSQTPSYAFgp---lINLSADAISAAKAGQTQKVAERQKSFGSSHVQSARLAAAE 372
jgi:Srot_0064       296 VHQFPAASPQPHVDMFEHIAGQFAGETSIPVESLglvnraNPTSAESYIASREDLIAEAEGATDDWSPAFQRSFTRALAI 375
CBG73129            303 QF--PEAQLKNFHDTINQLAQLVASLAGLPPHFLgyt-sqNPASADAIRSSESRLVKRAERRQREWGEAWEQVMRLALRI 379
CDA69854            301 DRELNQTQAQVAKEDVWDNALSILAIPNKQGNTGg-----DTQGAVELRNGWDFSKTRAKLKDPIVKSCEKRLAKVVLNI 375
cebbi:LBUCD034_0946 466 WNYVSSTGIKVTndcn--padNV------TITFTPNLPKNNQETMTLIQGLnqTGKF-------------SAQTLRELAE 524
Q8Y4Y0              407 GKFIEAYSGEVVel------dTI------TVDFDDSIAQDEDTTINRYTTAknQGMI-------------PLKIALQRAW 461 Listeria...
Q9A0P3              412 AKAYDLYQSEVPsm------dNI------SISLDDGVFTDRDAELDYWIKVvnAGFG-------------TREMAIQKVL 466 Streptoc...
SKLIDPC::KE3_1409   423 GKATGLYKGEIPel------eDI------SVNLDDGVFTDRNAELAYWMQMvsAGFA-------------PQRLGIQKTL 477
BAK21848            421 AGYKDLFPDKQPsfelvdgtyQV------SVHFNDGLFVDKNKQLDEDLKVslAGMM-------------PKKEFLKRNF 481
WP_011904463        424 SGDL-----------------SLaqnylgEVIWRDMEMKSLGAVADGLGKMaeQLGI-------------PRRGLWPRVP 473 Salinisp...
ABS03208            373 EGDE-----------------DIardvqlRVGWQDLEIRSISQAVDALGKAaqMLQV-------------PPQALWSRIP 422
jgi:Srot_0064       376 RNGLDSVPAEWV---------TI------APKWRSPIHLSRAAQADAG----------------------SKQLAAA--P 416
CBG73129            380 RDGEWDPRVM-----------SL------ETVWRDASTPTVAQAADAA----------------------VKKYSAKIVP 420
CDA69854            376 IRIKDHDLGISVr--------DF------DVQINHSPQDNMYTKAQTLQLLlqSGIHpliavrtvglwgdSEKTYLQSKP 441
cebbi:LBUCD034_0946 525 PITGiP--------AvQEQERSDDEGAQQDDR 548
Q8Y4Y0              462 NITD------------AEAEAWKEEIEKDVQA 481 Listeria monocytogenes
Q9A0P3              467 NVTE------------EKAQEIAAEINTGIVD 486 Streptococcus pyogenes serotype M1
SKLIDPC::KE3_1409   478 NVSE------------EEAKDYLVEINGELPP 497
BAK21848            482 GLSD------------ESAEEWLTALKEEQQE 501
WP_011904463        474 NVTR------------QELEDWARILKEDSPE 493 Salinispora tropica
ABS03208            423 GVEK------------SDVDEWAAMSRSSDPT 442
jgi:Srot_0064       417 WLADtevglgllgldeQQIRLALSQRRRAQGS 448
CBG73129            421 LRQTredl----gysqAQIARMEEQDREAAED 448
CDA69854            442 YFSN-L--------Y-KTIEDVEEQEKKAQEI 463
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