pfam05078: DUF679 (This model is not part of the current CDD release)
Protein of unknown function (DUF679)
This family includes members such as plant proteins AtDMPs 1-10 (Arabidopsis thaliana DUF679 domain membrane proteins 1 -10). The AtDMP proteins are predicted to have four transmembrane spans, with cytosolic amino- and carboxy-termini. DMP1 is a membrane protein that may be involved in membrane fission during breakdown of the ER and the tonoplast during leaf senescence and in membrane fusion during vacuole biogenesis in roots. Several DMP proteins are expressed in senescing organs (DMP1, -3, -4) or tissues that will stall later in development (DMP1, -2, -4, -7). These expression patterns strongly suggest involvement of several DMPs in various programmed cell death processes, e.g. senescence, dehiscence and abscission. AtDMP8 and AtDMP9 however, have been shown to facilitate gamete fusion during double fertilisation in flowering plants.
Jiyao W et al.(2023). "The conserved domain database in 2023.",