Conserved Protein Domain Family
SSXT

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pfam05030: SSXT 
SSXT protein (N-terminal region)
The SSXT or SS18 protein is involved in synovial sarcoma in humans. A SYT-SSX fusion gene resulting from the chromosomal translocation t(X;18) (p11;q11) is characteristic of synovial sarcomas. This translocation fuses the SSXT (SYT) gene from chromosome 18 to either of two homologous genes at Xp11, SSX1 or SSX2.
Statistics
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PSSM-Id: 398622
Aligned: 23 rows
Threshold Bit Score: 59.5979
Threshold Setting Gi: 1594612537
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
TDH66555      33 KQIGTEQIQAMLDENSSLIVEIIELNTQikhgkgtaqlGeFTEKLDKKRKNLNKNLMTLAKWADESSETSP 103 lettuce downy mildew
EGT48455      14 AADQQSTVQKLLDENSRLIDIIREYQNQ----------G-RADEAMKHQQLLHRNLMHLSNLADPFLLSQL 73  Caenorhabditis brenneri
Q567E9        14 AQINQETIQRLLDENDQLVRCISEYQQK----------G-RATECVQYQQILHRNIVYLGTIADASTEIQP 73  zebrafish
NP_001138658  14 AEVNQETIQRLLEENDQLIRCIVEYQNK----------G-RANECVQYQHVLHRNLIYLATIADANPTSAS 73  sheep
XP_003229053  14 AEVNQETLRRLMDENDQLIRCIVEYQNK----------G-RAAECMQLQHTLHRNLIYLATIADASASSNA 73  green anole
XP_015784271  13 GPTNSAQIQKMLDENSNLIQAVMEAQNK----------G-EAQKSVHLISTIHRNLLYLGSLSESNPNLAQ 72  two-spotted spider mite
XP_001631281  11 PEPSSQSVQELLDENTQLIQAIVDYQNK----------G-KAYESTQYQQLLHRNLVYLATLADSNQTGQP 70  starlet sea anemone
XP_002129850  15 SAVTQETIQKMLDENSRLIQCIVDEQQN----------G-RMQDCSRYQQILHRNLVWLATVADSNQSNGQ 74  vase tunicate
XP_001321434   4 QELTKEQIQQLLDENTHLIKVILTCQNE----------G-RIMDAMLYQTRFQLNLTQLAACADNHKHPSQ 63  Trichomonas vaginalis G3
NP_001017009  14 GQVGEDTVQRLLEENDQLIRCIVEYQNK----------G-RATECSQYQQILHRNLIYLASIADSGATNtv 73  tropical clawed frog
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